Basic Information:

  VIRBase ID:  

VHID00245655

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          IFRD1:  NR_120333     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	IFRD1
miRBase Accession/Entrez ID	MIMAT0003343	3475
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	PC4//TIS7

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	IFRD1	chr7:112099154(+) A-I      intronic chr7:112099172(+) A-I      intronic chr7:112099194(+) A-I      intronic chr7:112094387(+) A-I      intronic chr7:112095479(+) A-I      intronic chr7:112099220(+) A-I      intronic chr7:112094373(+) A-I      intronic chr7:112094390(+) A-I      intronic chr7:112094328(+) A-I      intronic chr7:112094996(+) A-I      intronic chr7:112105191(+) A-I      intronic chr7:112092349(+) A-I      5'UTR chr7:112116468(+) A-I      3'UTR chr7:112095132(+) A-I      intronic chr7:112095490(+) A-I      intronic chr7:112100358(+) A-I      intronic chr7:112095039(+) A-I      intronic chr7:112095522(+) A-I      intronic chr7:112083803(+) A-I      intronic chr7:112095420(+) A-I      intronic chr7:112116531(+) A-I      3'UTR chr7:112095021(+) A-I      intronic chr7:112095390(+) A-I      intronic chr7:112081119(+) A-I      intronic chr7:112113168(+) A-I      intronic chr7:112095067(+) A-I      intronic chr7:112095347(+) A-I      intronic chr7:112094323(+) A-I      intronic chr7:112094365(+) A-I      intronic chr7:112095128(+) A-I      intronic chr7:112095099(+) A-I      intronic chr7:112095353(+) A-I      intronic chr7:112095102(+) A-I      intronic chr7:112100500(+) A-I      intronic chr7:112099139(+) A-I      intronic chr7:112095051(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	IFRD1	chr7:112093700(+) A-I intron -    21960545   //22327324 chr7:112080179(+) T-C intron -    22484847 chr7:112080313(+) T-C intron -    22484847 chr7:112080319(+) T-C intron -    22484847 chr7:112083774(+) T-C intron -    22484847 chr7:112083886(+) T-C intron -    22484847 chr7:112094348(+) A-G intron -    22484847 chr7:112094365(+) A-G intron -    22484847 chr7:112094983(+) A-G intron -    22484847 chr7:112095015(+) A-G intron -    22484847 chr7:112095021(+) A-G intron -    22484847 chr7:112095039(+) A-G intron -    22484847 chr7:112095051(+) A-G intron -    22484847 chr7:112095067(+) A-G intron -    22484847 chr7:112095102(+) A-G intron -    22484847 chr7:112095128(+) A-G intron -    22484847 chr7:112095132(+) A-G intron -    22484847 chr7:112095171(+) A-G intron -    22484847 chr7:112095347(+) A-G intron -    22484847 chr7:112095351(+) A-G intron -    22484847 chr7:112095353(+) A-G intron -    22484847 chr7:112095420(+) A-G intron -    22484847 chr7:112099159(+) A-G intron -    22484847 chr7:112100358(+) A-G intron -    22484847 chr7:112116644(+) A-G intron -    22484847 chr7:112093700(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	IFRD1	chr7:112063204-112063205(+) m6A 5'UTR       24981863 chr7:112063209-112063210(+) m6A 5'UTR       24981863 chr7:112090539-112090540(+) m6A 5'UTR//intron       - chr7:112090638-112090639(+) m6A 5'UTR//intron       - chr7:112096082-112096083(+) m6A CDS       27773535 chr7:112096092-112096093(+) m6A CDS       27773535 chr7:112098363-112098364(+) m6A 3'UTR//intron       - chr7:112099007-112099008(+) m6A CDS//exon       - chr7:112099015-112099016(+) m6A CDS//exon       - chr7:112115817-112115818(+) m6A 3'UTR//exon//intron       27773535 chr7:112115827-112115828(+) m6A 3'UTR//exon//intron       27773535 chr7:112115848-112115849(+) m6A 3'UTR//exon//intron       27773535 chr7:112116072-112116073(+) m6A 3'UTR//exon//intron       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	IFRD1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: IFRD1

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid//Targetscan
Support Database	VmiReg