Basic Information:

  VIRBase ID:  

VHID00245440

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          GABBR1:  NM_021903     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	GABBR1
miRBase Accession/Entrez ID	MIMAT0003343	2550
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	GABABR1//GABBR1-3//GB1//GPRC3A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	GABBR1	chr6:29585344(-) A-I      intronic chr6:29585358(-) A-I      intronic chr6:29584426(-) A-I      intronic chr6:29585274(-) A-I      intronic chr6:29585298(-) A-I      intronic chr6:29584423(-) A-I      intronic chr6:29587412(-) A-I      intronic chr6:29584509(-) A-I      intronic chr6:29582818(-) A-I      intronic chr6:29585147(-) A-I      intronic chr6:29585151(-) A-I      intronic chr6:29585164(-) A-I      intronic chr6:29585216(-) A-I      intronic chr6:29584399(-) A-I      intronic chr6:29582812(-) A-I      intronic chr6:29585257(-) A-I      intronic chr6:29583006(-) A-I      intronic chr6:29585272(-) A-I      intronic chr6:29583722(-) A-I      intronic chr6:29582986(-) A-I      intronic chr6:29582833(-) A-I      intronic chr6:29585280(-) A-I      intronic chr6:29583128(-) A-I      intronic chr6:29585352(-) A-I      intronic chr6:29585350(-) A-I      intronic chr6:29583919(-) A-I      intronic chr6:29583238(-) A-I      intronic chr6:29585131(-) A-I      intronic chr6:29585146(-) A-I      intronic chr6:29583000(-) A-I      intronic chr6:29585297(-) A-I      intronic chr6:29585258(-) A-I      intronic chr6:29585255(-) A-I      intronic chr6:29584456(-) A-I      intronic chr6:29585252(-) A-I      intronic chr6:29583017(-) A-I      intronic chr6:29582899(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	GABBR1	chr6:29523431-29523432(-) m6A 3'UTR       27773535 chr6:29523589-29523590(-) m6A 3'UTR       27773535 chr6:29523740-29523741(-) m6A 3'UTR       24209618//24981863//28052920//27773535//22575960 chr6:29523769-29523770(-) m6A 3'UTR       24209618//24981863//28052920//27773535//22575960 chr6:29523793-29523794(-) m6A 3'UTR       24209618//24981863//28052920//27773535//22575960 chr6:29523937-29523938(-) m6A 3'UTR       24209618//27773535//22575960 chr6:29570102-29570103(-) m6A 3'UTR//intron       27773535 chr6:29570110-29570111(-) m6A 3'UTR//intron       27773535 chr6:29571382-29571383(-) m6A 3'UTR//CDS//exon       27371828//27773536 chr6:29571406-29571407(-) m6A 3'UTR//CDS//exon       27371828//27773536 chr6:29571472-29571473(-) m6A 3'UTR//CDS//exon       24981863//27371828//27773536 chr6:29572291-29572292(-) m6A 3'UTR//CDS//exon       24981863//27371828//27773536 chr6:29572298-29572299(-) m6A 3'UTR//CDS//exon       24981863//27371828//27773536 chr6:29572356-29572357(-) m6A 3'UTR//CDS//exon       27371828//27773536 chr6:29572367-29572368(-) m6A 3'UTR//CDS//exon       27371828 chr6:29591147-29591148(-) m6A 3'UTR//CDS//exon       - chr6:29591217-29591218(-) m6A 3'UTR//CDS//exon       - chr6:29591676-29591677(-) m6A 3'UTR//CDS//exon       - chr6:29595296-29595297(-) m6A 3'UTR//CDS//intron       - chr6:29595308-29595309(-) m6A 3'UTR//CDS//intron       - chr6:29597704-29597705(-) m6A exon//intron       24981863 chr6:29597741-29597742(-) m6A exon//intron       24981863 chr6:29597758-29597759(-) m6A exon//intron       24981863 chr6:29597897-29597898(-) m6A exon//intron       27773535 chr6:29597981-29597982(-) m6A exon//intron       24981863//27773535 chr6:29598121-29598122(-) m6A exon//intron       - chr6:29598224-29598225(-) m6A exon//intron       24284625//24981863 chr6:29599315-29599316(-) m6A CDS//exon       27773536 chr6:29600098-29600099(-) m6A CDS//exon       27773536 chr6:29600509-29600510(-) m6A 5'UTR//intron       27773536 chr6:29600775-29600776(-) m6A 5'UTR//exon//intron       25456834//27773536 chr6:29600816-29600817(-) m6A 5'UTR//exon//intron       25456834//27773536 chr6:29600821-29600822(-) m1A 5'UTR//exon//intron       26863196

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	GABBR1	Chromatin K562 cells     - Cytosol K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: GABBR1

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg