Basic Information:

  VIRBase ID:  

VHID00245332

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          EIF5A:  NM_001143761     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	EIF5A
miRBase Accession/Entrez ID	MIMAT0003343	1984
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	eIF-4D//EIF-5A//EIF5A1//eIF5AI

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	EIF5A	chr17:7210352-7210353(+) m6A 5'UTR       25456834//24981863 chr17:7210374-7210375(+) m6A CDS       25456834//24981863 chr17:7210383-7210384(+) m6A CDS       25456834//24981863 chr17:7210395-7210396(+) m6A CDS       25456834//24981863 chr17:7210661-7210662(+) m6A exon//intron       25456834//24981863 chr17:7210954-7210955(+) m6A 5'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960 chr17:7211407-7211408(+) m6A 5'UTR//intron       24209618//25456834//24981863//22575960 chr17:7211862-7211863(+) m6A 5'UTR//intron       24209618//22575960 chr17:7212970-7212971(+) m6A CDS//exon       24209618//22575960 chr17:7212978-7212979(+) m6A CDS//exon       24209618//22575960 chr17:7213095-7213096(+) m6A CDS//exon       22575960 chr17:7213271-7213272(+) m6A exon//intron       27773535 chr17:7213528-7213529(+) m6A exon//intron       27773535 chr17:7213717-7213718(+) m6A exon//intron       27773535 chr17:7214708-7214709(+) m6A CDS       22575960 chr17:7214729-7214730(+) m6A CDS       22575960 chr17:7214750-7214751(+) m6A CDS       22575960 chr17:7214864-7214865(+) m6A CDS//intron       22575960 chr17:7215171-7215172(+) m6A 3'UTR       24284625//22575960 chr17:7215227-7215228(+) m6A 3'UTR       24284625//22575960 chr17:7215568-7215569(+) m6A 3'UTR       24284625//22575960 chr17:7215575-7215576(+) m6A 3'UTR       24284625//22575960 chr17:7215609-7215610(+) m6A 3'UTR       24284625//22575960 chr17:7215650-7215651(+) m6A 3'UTR       24284625//22575960

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	EIF5A	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: EIF5A

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid
Support Database	VmiReg