Basic Information:

  VIRBase ID:  

VHID00244925

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          ALPP:  NM_001632     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	ALPP
miRBase Accession/Entrez ID	MIMAT0003343	250
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ALP//ALPI//IAP//PALP//PLAP//PLAP-1

RNA Editing:

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ALPP	chr2:233244910(+) A-I exon CDS    15342557 chr2:233245167(+) A-I exon CDS    15342557 chr2:233245190(+) A-I exon CDS    15342557 chr2:233245715(+) A-I exon CDS    15342557 chr2:233245729(+) A-I exon CDS    15342557 chr2:233246559(+) A-I exon 3'UTR    15342557

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ALPP	chr2:233243414-233243415(+) m6A 5'UTR       22575960 chr2:233243435-233243436(+) m6A 5'UTR//exon       22575960 chr2:233243510-233243511(+) m6A 5'UTR//exon       22575960 chr2:233243692-233243693(+) m6A CDS//exon       22575960 chr2:233243698-233243699(+) m6A CDS//exon       22575960 chr2:233243707-233243708(+) m6A CDS//exon       22575960 chr2:233243760-233243761(+) m6A CDS//exon       22575960 chr2:233243773-233243774(+) m6A CDS//exon       22575960 chr2:233243963-233243964(+) m6A CDS//exon       22575960 chr2:233243996-233243997(+) m6A CDS//exon       22575960 chr2:233244235-233244236(+) m6A CDS//exon       22575960 chr2:233244250-233244251(+) m6A CDS//exon       24284625//22575960 chr2:233244303-233244304(+) m6A CDS//exon       24284625//22575960 chr2:233244332-233244333(+) Y CDS//exon       25219674 chr2:233244548-233244549(+) m6A CDS       22575960 chr2:233244608-233244609(+) m6A CDS       22575960 chr2:233244638-233244639(+) m6A CDS       22575960 chr2:233244937-233244938(+) m6A CDS       22575960 chr2:233244944-233244945(+) m6A CDS       22575960 chr2:233244979-233244980(+) m6A CDS       22575960 chr2:233245148-233245149(+) m6A CDS       22575960 chr2:233245178-233245179(+) m6A CDS       22575960 chr2:233245350-233245351(+) m6A CDS       22575960 chr2:233245374-233245375(+) m6A CDS       22575960 chr2:233245386-233245387(+) m6A CDS       22575960 chr2:233245984-233245985(+) m6A CDS//exon       22575960 chr2:233246253-233246254(+) m6A CDS//exon       22575960 chr2:233246328-233246329(+) m6A CDS//exon       22575960 chr2:233246469-233246470(+) m6A CDS//exon       24284625//22575960 chr2:233246633-233246634(+) m6A 3'UTR//exon       24284625//24209618//22575960 chr2:233246660-233246661(+) m6A 3'UTR//exon       24284625//24209618//22575960 chr2:233246679-233246680(+) m6A 3'UTR//exon       24284625//24209618//22575960 chr2:233246702-233246703(+) m6A 3'UTR//exon       24284625//24209618//22575960 chr2:233246724-233246725(+) m6A 3'UTR//exon       24284625//24209618//22575960 chr2:233246848-233246849(+) m6A 3'UTR//exon       22575960 chr2:233246896-233246897(+) m6A 3'UTR//exon       22575960 chr2:233246904-233246905(+) m6A 3'UTR//exon       22575960 chr2:233247180-233247181(+) m6A 3'UTR//exon       24284625//22575960 chr2:233247212-233247213(+) m6A 3'UTR//exon       24284625//22575960 chr2:233247220-233247221(+) m6A 3'UTR//exon       24284625//22575960 chr2:233247250-233247251(+) m6A 3'UTR//exon       24284625//22575960 chr2:233247288-233247289(+) m6A 3'UTR//exon       24284625//22575960 chr2:233247372-233247373(+) m6A 3'UTR       24284625//22575960 chr2:233247395-233247396(+) m6A 3'UTR       24284625//22575960 chr2:233247458-233247459(+) m6A 3'UTR       22575960

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ALPP	Endoplasmic reticulum COS-7 cells     22679391 Endoplasmic reticulum COS-7 cells     24019514 Endoplasmic reticulum Glioblastoma cells (U-87)     26272916 Exosome Blood     - Nucleus COS-7 cells     22679391 Nucleus COS-7 cells     24019514

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: ALPP

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg