Basic Information:

  VIRBase ID:  

VHID00239745

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US4-5p:  MIMAT0003341          EIF1AX:  NM_001412     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US4-5p	EIF1AX
miRBase Accession/Entrez ID	MIMAT0003341	1964
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	eIF-1A//eIF-4C//EIF1A//EIF1AP1//EIF4C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	EIF1AX	chrX:20156555(-) A-I      intronic chrX:20156535(-) A-I      intronic chrX:20156554(-) A-I      intronic chrX:20156530(-) A-I      intronic chrX:20148247(-) A-I      intronic chrX:20148299(-) A-I      intronic chrX:20148321(-) A-I      intronic chrX:20149680(-) A-I      intronic chrX:20156260(-) A-I      intronic chrX:20149740(-) A-I      intronic chrX:20147507(-) A-I      intronic chrX:20156492(-) A-I      intronic chrX:20149903(-) A-I      intronic chrX:20156465(-) A-I      intronic chrX:20147511(-) A-I      intronic chrX:20147436(-) A-I      intronic chrX:20149902(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	EIF1AX	chrX:20147511(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	EIF1AX	chrX:20143387-20143388(-) m6A 3'UTR       24981863 chrX:20146417-20146418(-) m6A 3'UTR       24981863 chrX:20148710-20148711(-) m6A CDS       27773535 chrX:20152081-20152082(-) m6A CDS       27773535 chrX:20152105-20152106(-) m6A CDS       27773535 chrX:20154386-20154387(-) Y intron       26075521 chrX:20156681-20156682(-) m6A CDS//intron       24981863//28052920//27773535//27371828//22575960 chrX:20156724-20156725(-) m6A CDS//intron       24981863//28052920//27773535//27371828

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-US4-5p	Exosome B cell line (Raji)|Primary dendritic cells|T cell line (J77)     21505438
	EIF1AX	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US4-5p
Interactor2: EIF1AX

Evidence Support:

Prediction-Evidence	miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg