Basic Information:

  VIRBase ID:  

VHID00238527

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US33-5p:  MIMAT0001584          MCPH1:  NR_136159     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US33-5p	MCPH1
miRBase Accession/Entrez ID	MIMAT0001584	79648
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BRIT1//MCT

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MCPH1	chr8:6315006(+) A-I      intronic chr8:6315019(+) A-I      intronic chr8:6315038(+) A-I      intronic chr8:6315055(+) A-I      intronic chr8:6316364(+) A-I      intronic chr8:6378100(+) A-I      intronic chr8:6365784(+) A-I      intronic chr8:6365794(+) A-I      intronic chr8:6365812(+) A-I      intronic chr8:6365813(+) A-I      intronic chr8:6494065(+) A-I      intronic chr8:6494113(+) A-I      intronic chr8:6494020(+) A-I      intronic chr8:6499226(+) A-I      intronic chr8:6499162(+) A-I      intronic chr8:6499040(+) A-I      intronic chr8:6497520(+) A-I      intronic chr8:6497512(+) A-I      intronic chr8:6497495(+) A-I      intronic chr8:6267560(+) A-I      intronic chr8:6494101(+) A-I      intronic chr8:6480100(+) A-I      intronic chr8:6431675(+) A-I      intronic chr8:6494088(+) A-I      intronic chr8:6494026(+) A-I      intronic chr8:6480488(+) A-I      intronic chr8:6397237(+) A-I      intronic chr8:6387819(+) A-I      intronic chr8:6397233(+) A-I      intronic chr8:6387887(+) A-I      intronic chr8:6387809(+) A-I      intronic chr8:6383870(+) A-I      intronic chr8:6383809(+) A-I      intronic chr8:6383805(+) A-I      intronic chr8:6383725(+) A-I      intronic chr8:6382965(+) A-I      intronic chr8:6381369(+) A-I      intronic chr8:6381284(+) A-I      intronic chr8:6381175(+) A-I      intronic chr8:6380599(+) A-I      intronic chr8:6380593(+) A-I      intronic chr8:6399334(+) A-I      intronic chr8:6380308(+) A-I      intronic chr8:6380279(+) A-I      intronic chr8:6330957(+) A-I      intronic chr8:6380184(+) A-I      intronic chr8:6330129(+) A-I      intronic chr8:6324344(+) A-I      intronic chr8:6323602(+) A-I      intronic chr8:6380174(+) A-I      intronic chr8:6380135(+) A-I      intronic chr8:6380134(+) A-I      intronic chr8:6323593(+) A-I      intronic chr8:6380133(+) A-I      intronic chr8:6494024(+) A-I      intronic chr8:6494022(+) A-I      intronic chr8:6494021(+) A-I      intronic chr8:6493117(+) A-I      intronic chr8:6493048(+) A-I      intronic chr8:6493041(+) A-I      intronic chr8:6380111(+) A-I      intronic chr8:6430213(+) A-I      intronic chr8:6493036(+) A-I      intronic chr8:6378034(+) A-I      intronic chr8:6493023(+) A-I      intronic chr8:6493022(+) A-I      intronic chr8:6492995(+) A-I      intronic chr8:6485313(+) A-I      intronic chr8:6316261(+) A-I      intronic chr8:6316901(+) A-I      intronic chr8:6485289(+) A-I      intronic chr8:6485228(+) A-I      intronic chr8:6483293(+) A-I      intronic chr8:6333798(+) A-I      intronic chr8:6336667(+) A-I      intronic chr8:6333797(+) A-I      intronic chr8:6333788(+) A-I      intronic chr8:6331104(+) A-I      intronic chr8:6331059(+) A-I      intronic chr8:6272853(+) A-I      intronic chr8:6273014(+) A-I      intronic chr8:6337155(+) A-I      intronic chr8:6337706(+) A-I      intronic chr8:6483292(+) A-I      intronic chr8:6480596(+) A-I      intronic chr8:6480595(+) A-I      intronic chr8:6480594(+) A-I      intronic chr8:6480588(+) A-I      intronic chr8:6337725(+) A-I      intronic chr8:6351649(+) A-I      intronic chr8:6365716(+) A-I      intronic chr8:6365722(+) A-I      intronic chr8:6365820(+) A-I      intronic chr8:6365823(+) A-I      intronic chr8:6365847(+) A-I      intronic chr8:6365849(+) A-I      intronic chr8:6273096(+) A-I      intronic chr8:6365850(+) A-I      intronic chr8:6273097(+) A-I      intronic chr8:6274253(+) A-I      intronic chr8:6276878(+) A-I      intronic chr8:6294370(+) A-I      intronic chr8:6294829(+) A-I      intronic chr8:6307075(+) A-I      intronic chr8:6307086(+) A-I      intronic chr8:6307104(+) A-I      intronic chr8:6314886(+) A-I      intronic chr8:6314940(+) A-I      intronic chr8:6315020(+) A-I      intronic chr8:6315096(+) A-I      intronic chr8:6315790(+) A-I      intronic chr8:6315838(+) A-I      intronic chr8:6315839(+) A-I      intronic chr8:6315841(+) A-I      intronic chr8:6315842(+) A-I      intronic chr8:6315910(+) A-I      intronic chr8:6316246(+) A-I      intronic chr8:6365944(+) A-I      intronic chr8:6378029(+) A-I      intronic chr8:6314927(+) A-I      intronic chr8:6493793(+) A-I      intronic chr8:6443615(+) A-I      intronic chr8:6387120(+) A-I      intronic chr8:6383716(+) A-I      intronic chr8:6337787(+) A-I      intronic chr8:6314999(+) A-I      intronic chr8:6314983(+) A-I      intronic chr8:6314961(+) A-I      intronic chr8:6308333(+) A-I      intronic chr8:6294938(+) A-I      intronic chr8:6494070(+) A-I      intronic chr8:6314905(+) A-I      intronic chr8:6314920(+) A-I      intronic chr8:6314942(+) A-I      intronic chr8:6314949(+) A-I      intronic chr8:6314964(+) A-I      intronic chr8:6314965(+) A-I      intronic chr8:6314973(+) A-I      intronic chr8:6501008(+) A-I      3'UTR chr8:6500975(+) A-I      3'UTR chr8:6500960(+) A-I      3'UTR chr8:6500941(+) A-I      3'UTR chr8:6500929(+) A-I      3'UTR chr8:6500925(+) A-I      3'UTR chr8:6500912(+) A-I      3'UTR chr8:6500938(+) A-I      3'UTR chr8:6500872(+) A-I      3'UTR chr8:6500811(+) A-I      3'UTR chr8:6500885(+) A-I      3'UTR chr8:6500842(+) A-I      3'UTR chr8:6500865(+) A-I      3'UTR chr8:6316332(+) A-I      intronic chr8:6380538(+) A-I      intronic chr8:6326603(+) A-I      intronic chr8:6381293(+) A-I      intronic chr8:6324207(+) A-I      intronic chr8:6336690(+) A-I      intronic chr8:6268369(+) A-I      intronic chr8:6381370(+) A-I      intronic chr8:6316340(+) A-I      intronic chr8:6364437(+) A-I      intronic chr8:6290878(+) A-I      intronic chr8:6323550(+) A-I      intronic chr8:6383699(+) A-I      intronic chr8:6316185(+) A-I      intronic chr8:6314910(+) A-I      intronic chr8:6267681(+) A-I      intronic chr8:6314856(+) A-I      intronic chr8:6316388(+) A-I      intronic chr8:6380175(+) A-I      intronic chr8:6326524(+) A-I      intronic chr8:6314891(+) A-I      intronic chr8:6380618(+) A-I      intronic chr8:6354859(+) A-I      intronic chr8:6326481(+) A-I      intronic chr8:6268429(+) A-I      intronic chr8:6364519(+) A-I      intronic chr8:6333871(+) A-I      intronic chr8:6267590(+) A-I      intronic chr8:6315051(+) A-I      intronic chr8:6316442(+) A-I      intronic chr8:6315738(+) A-I      intronic chr8:6336528(+) A-I      intronic chr8:6314896(+) A-I      intronic chr8:6500966(+) A-I      3'UTR chr8:6500903(+) A-I      3'UTR chr8:6501006(+) A-I      3'UTR chr8:6500927(+) A-I      3'UTR chr8:6500952(+) A-I      3'UTR chr8:6500886(+) A-I      3'UTR chr8:6500879(+) A-I      3'UTR chr8:6500969(+) A-I      3'UTR chr8:6315046(+) A-I      intronic chr8:6314948(+) A-I      intronic chr8:6365709(+) A-I      intronic chr8:6337844(+) A-I      intronic chr8:6480420(+) A-I      intronic chr8:6316836(+) A-I      intronic chr8:6274394(+) A-I      intronic chr8:6324317(+) A-I      intronic chr8:6316230(+) A-I      intronic chr8:6316853(+) A-I      intronic chr8:6434158(+) A-I      intronic chr8:6294838(+) A-I      intronic chr8:6326433(+) A-I      intronic chr8:6316464(+) A-I      intronic chr8:6337830(+) A-I      intronic chr8:6316389(+) A-I      intronic chr8:6378017(+) A-I      intronic chr8:6290880(+) A-I      intronic chr8:6333816(+) A-I      intronic chr8:6337847(+) A-I      intronic chr8:6336604(+) A-I      intronic chr8:6314975(+) A-I      intronic chr8:6316311(+) A-I      intronic chr8:6380033(+) A-I      intronic chr8:6330114(+) A-I      intronic chr8:6326454(+) A-I      intronic chr8:6308467(+) A-I      intronic chr8:6381180(+) A-I      intronic chr8:6314976(+) A-I      intronic chr8:6380612(+) A-I      intronic chr8:6314858(+) A-I      intronic chr8:6354939(+) A-I      intronic chr8:6492993(+) A-I      intronic chr8:6316305(+) A-I      intronic chr8:6276268(+) A-I      intronic chr8:6315806(+) A-I      intronic chr8:6316007(+) A-I      intronic chr8:6342767(+) A-I      intronic chr8:6316816(+) A-I      intronic chr8:6365761(+) A-I      intronic chr8:6316922(+) A-I      intronic chr8:6316871(+) A-I      intronic chr8:6315846(+) A-I      intronic chr8:6336624(+) A-I      intronic chr8:6326464(+) A-I      intronic chr8:6336644(+) A-I      intronic chr8:6333870(+) A-I      intronic chr8:6485170(+) A-I      intronic chr8:6274260(+) A-I      intronic chr8:6336665(+) A-I      intronic chr8:6316877(+) A-I      intronic chr8:6315878(+) A-I      intronic chr8:6326635(+) A-I      intronic chr8:6315116(+) A-I      intronic chr8:6326621(+) A-I      intronic chr8:6324318(+) A-I      intronic chr8:6378046(+) A-I      intronic chr8:6325355(+) A-I      intronic chr8:6380725(+) A-I      intronic chr8:6316367(+) A-I      intronic chr8:6316292(+) A-I      intronic chr8:6326610(+) A-I      intronic chr8:6336536(+) A-I      intronic chr8:6387870(+) A-I      intronic chr8:6316376(+) A-I      intronic chr8:6316860(+) A-I      intronic chr8:6333895(+) A-I      intronic chr8:6337749(+) A-I      intronic chr8:6381388(+) A-I      intronic chr8:6316266(+) A-I      intronic chr8:6337827(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MCPH1	chr8:6289701(+) A-I intron -    22327324 chr8:6431676(+) A-G intron -    22484847 chr8:6431898(+) A-G intron -    22484847 chr8:6267681(+) A-G intron -    22484847 chr8:6268429(+) A-G intron -    22484847 chr8:6268532(+) A-G intron -    22484847 chr8:6272857(+) A-G intron -    22484847 chr8:6273020(+) A-G intron -    22484847 chr8:6274260(+) A-G intron -    22484847 chr8:6289701(+) A-G intron -    22484847 chr8:6289705(+) A-G intron -    22484847 chr8:6289713(+) A-G intron -    22484847 chr8:6290878(+) A-G intron -    22484847 chr8:6290880(+) A-G intron -    22484847 chr8:6294838(+) A-G intron -    22484847 chr8:6314856(+) A-G intron -    22484847 chr8:6314896(+) A-G intron -    22484847 chr8:6315046(+) A-G intron -    22484847 chr8:6315051(+) A-G intron -    22484847 chr8:6315732(+) A-G intron -    22484847 chr8:6315739(+) A-G intron -    22484847 chr8:6315764(+) T-C intron -    22484847 chr8:6315846(+) A-G intron -    22484847 chr8:6315872(+) A-G intron -    22484847 chr8:6315963(+) A-G intron -    22484847 chr8:6316214(+) A-G intron -    22484847 chr8:6316230(+) A-G intron -    22484847 chr8:6316292(+) A-G intron -    22484847 chr8:6316305(+) A-G intron -    22484847 chr8:6316311(+) A-G intron -    22484847 chr8:6316340(+) A-G intron -    22484847 chr8:6316367(+) A-G intron -    22484847 chr8:6316442(+) A-G intron -    22484847 chr8:6316860(+) A-G intron -    22484847 chr8:6316871(+) A-G intron -    22484847 chr8:6316896(+) A-G intron -    22484847 chr8:6316897(+) A-G intron -    22484847 chr8:6337749(+) A-G intron -    22484847 chr8:6337847(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MCPH1	chr8:6266837-6266838(+) m6A CDS       24981863 chr8:6266855-6266856(+) m6A CDS       24981863 chr8:6293604-6293605(+) m6A CDS       24981863 chr8:6293673-6293674(+) m6A CDS       24981863 chr8:6301964-6301965(+) m6A CDS       24981863 chr8:6302144-6302145(+) m6A CDS       24284625//24981863//27773535//22608085 chr8:6302286-6302287(+) m6A CDS       24284625//24981863//27773535//22608085 chr8:6302406-6302407(+) Cm CDS       - chr8:6302417-6302418(+) m6A CDS       24284625//24981863//22608085 chr8:6302439-6302440(+) m6A CDS       24284625//24209618//24981863//22608085 chr8:6302599-6302600(+) m6A CDS       24284625//24209618//24981863//22608085 chr8:6302644-6302645(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr8:6302650-6302651(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr8:6302680-6302681(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr8:6302701-6302702(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr8:6302775-6302776(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr8:6302834-6302835(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr8:6302853-6302854(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr8:6302930-6302931(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr8:6302957-6302958(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr8:6302985-6302986(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr8:6303044-6303045(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr8:6303108-6303109(+) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085 chr8:6303220-6303221(+) m6A 3'UTR//intron       24981863//27773535//22608085 chr8:6303255-6303256(+) m6A 3'UTR//intron       24981863//27773535//22608085 chr8:6303263-6303264(+) m6A 3'UTR//intron       24981863//27773535//22608085 chr8:6303302-6303303(+) m6A 3'UTR//intron       24981863//27773535//22608085 chr8:6304082-6304083(+) m6A 3'UTR//intron       24981863 chr8:6312676-6312677(+) m6A CDS       24981863 chr8:6312723-6312724(+) m6A CDS//exon       24981863 chr8:6312733-6312734(+) m6A CDS//exon       24981863 chr8:6500550-6500551(+) m6A CDS//exon       24981863//22608085 chr8:6500613-6500614(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr8:6500639-6500640(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr8:6500644-6500645(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr8:6500660-6500661(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr8:6500719-6500720(+) m6A 3'UTR//exon       24981863//22608085 chr8:6502058-6502059(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MCPH1	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Membrane K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US33-5p
Interactor2: MCPH1

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg