Basic Information:

  VIRBase ID:  

VHID00237992

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US33-5p:  MIMAT0001584          RRP15:  NM_016052     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US33-5p	RRP15
miRBase Accession/Entrez ID	MIMAT0001584	51018
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CGI-115//KIAA0507

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RRP15	chr1:218499413(+) A-I      intronic chr1:218499628(+) A-I      intronic chr1:218499433(+) A-I      intronic chr1:218499437(+) A-I      intronic chr1:218499446(+) A-I      intronic chr1:218499460(+) A-I      intronic chr1:218499593(+) A-I      intronic chr1:218499638(+) A-I      intronic chr1:218499597(+) A-I      intronic chr1:218502488(+) A-I      intronic chr1:218499623(+) A-I      intronic chr1:218499391(+) A-I      intronic chr1:218502505(+) A-I      intronic chr1:218502509(+) A-I      intronic chr1:218499461(+) A-I      intronic chr1:218502510(+) A-I      intronic chr1:218499598(+) A-I      intronic chr1:218499627(+) A-I      intronic chr1:218499392(+) A-I      intronic chr1:218499601(+) A-I      intronic chr1:218488255(+) A-I      intronic chr1:218465375(+) A-I      intronic chr1:218500725(+) A-I      intronic chr1:218499554(+) A-I      intronic chr1:218499527(+) A-I      intronic chr1:218469867(+) A-I      intronic chr1:218500843(+) A-I      intronic chr1:218501853(+) A-I      intronic chr1:218465198(+) A-I      intronic chr1:218501847(+) A-I      intronic chr1:218465199(+) A-I      intronic chr1:218465204(+) A-I      intronic chr1:218501842(+) A-I      intronic chr1:218501890(+) A-I      intronic chr1:218488073(+) A-I      intronic chr1:218501825(+) A-I      intronic chr1:218501802(+) A-I      intronic chr1:218464270(+) A-I      intronic chr1:218488880(+) A-I      intronic chr1:218501793(+) A-I      intronic chr1:218464280(+) A-I      intronic chr1:218465413(+) A-I      intronic chr1:218469873(+) A-I      intronic chr1:218501987(+) A-I      intronic chr1:218500829(+) A-I      intronic chr1:218465322(+) A-I      intronic chr1:218488899(+) A-I      intronic chr1:218500787(+) A-I      intronic chr1:218500774(+) A-I      intronic chr1:218499528(+) A-I      intronic chr1:218488213(+) A-I      intronic chr1:218500898(+) A-I      intronic chr1:218500827(+) A-I      intronic chr1:218465013(+) A-I      intronic chr1:218501882(+) A-I      intronic chr1:218464666(+) A-I      intronic chr1:218500784(+) A-I      intronic chr1:218464382(+) A-I      intronic chr1:218500762(+) A-I      intronic chr1:218499383(+) A-I      intronic chr1:218502744(+) A-I      intronic chr1:218500811(+) A-I      intronic chr1:218502727(+) A-I      intronic chr1:218464978(+) A-I      intronic chr1:218465054(+) A-I      intronic chr1:218500674(+) A-I      intronic chr1:218505202(+) A-I      3'UTR chr1:218465313(+) A-I      intronic chr1:218501884(+) A-I      intronic chr1:218487471(+) A-I      intronic chr1:218489072(+) A-I      intronic chr1:218501826(+) A-I      intronic chr1:218491099(+) A-I      intronic chr1:218464383(+) A-I      intronic chr1:218505205(+) A-I      3'UTR chr1:218487459(+) A-I      intronic chr1:218488080(+) A-I      intronic chr1:218465088(+) A-I      intronic chr1:218500826(+) A-I      intronic chr1:218488096(+) A-I      intronic chr1:218501750(+) A-I      intronic chr1:218464518(+) A-I      intronic chr1:218500920(+) A-I      intronic chr1:218488978(+) A-I      intronic chr1:218488272(+) A-I      intronic chr1:218488214(+) A-I      intronic chr1:218464927(+) A-I      intronic chr1:218502717(+) A-I      intronic chr1:218501827(+) A-I      intronic chr1:218488975(+) A-I      intronic chr1:218488079(+) A-I      intronic chr1:218488909(+) A-I      intronic chr1:218465134(+) A-I      intronic chr1:218502647(+) A-I      intronic chr1:218488904(+) A-I      intronic chr1:218500786(+) A-I      intronic chr1:218465273(+) A-I      intronic chr1:218500832(+) A-I      intronic chr1:218502514(+) A-I      intronic chr1:218496655(+) A-I      intronic chr1:218500908(+) A-I      intronic chr1:218464524(+) A-I      intronic chr1:218501749(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RRP15	chr1:218464382(+) A-G intron -    22484847 chr1:218465013(+) A-G intron -    22484847 chr1:218465054(+) A-G intron -    22484847 chr1:218488080(+) A-G intron -    22484847 chr1:218488213(+) A-G intron -    22484847 chr1:218488214(+) A-G intron -    22484847 chr1:218488904(+) A-G intron -    22484847 chr1:218488909(+) A-G intron -    22484847 chr1:218488978(+) A-G intron -    22484847 chr1:218501826(+) A-G intron -    22484847 chr1:218501827(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RRP15	chr1:218458677-218458678(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr1:218458701-218458702(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22608085 chr1:218458712-218458713(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22608085 chr1:218458724-218458725(+) m1A CDS//exon       26863196 chr1:218458779-218458780(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085 chr1:218475656-218475657(+) m6A CDS//exon       24209618//24981863//27773535//22608085 chr1:218475757-218475758(+) m6A CDS//exon       24209618//24981863//27773535//22608085 chr1:218475805-218475806(+) m6A CDS//exon       24209618//24981863//27773535//22608085 chr1:218475819-218475820(+) m6A CDS//exon       24209618//24981863//27773535//22608085 chr1:218475882-218475883(+) m6A CDS//exon       24209618//24981863//27773535//22608085 chr1:218475897-218475898(+) m6A CDS//exon       24209618//24981863//27773535//22608085 chr1:218475965-218475966(+) m6A exon//intron       24981863//27773535//22608085 chr1:218478427-218478428(+) m6A CDS       24981863//27773535//22608085 chr1:218478435-218478436(+) m6A CDS       24981863//27773535//22608085 chr1:218480805-218480806(+) m6A CDS       24981863//27773535//22608085 chr1:218480938-218480939(+) m6A CDS       24209618//25456834//24981863//26404942//27773535//22608085 chr1:218480958-218480959(+) m6A CDS       24209618//25456834//24981863//26404942//27773535//22608085 chr1:218480970-218480971(+) m6A CDS       24209618//25456834//24981863//26404942//27773535//22608085 chr1:218504365-218504366(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr1:218504371-218504372(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr1:218504402-218504403(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr1:218504540-218504541(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr1:218504611-218504612(+) m6A 3'UTR       24981863 chr1:218504778-218504779(+) m6A 3'UTR       27773535 chr1:218504818-218504819(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	RRP15	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US33-5p
Interactor2: RRP15

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg