Basic Information:

  VIRBase ID:  

VHID00237823

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US33-5p:  MIMAT0001584          RYBP:  NM_012234     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US33-5p	RYBP
miRBase Accession/Entrez ID	MIMAT0001584	23429
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	AAP1//APAP-1//DEDAF//YEAF1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RYBP	chr3:72485152(-) A-I      intronic chr3:72485339(-) A-I      intronic chr3:72485384(-) A-I      intronic chr3:72492431(-) A-I      intronic chr3:72492421(-) A-I      intronic chr3:72442260(-) A-I      intronic chr3:72442288(-) A-I      intronic chr3:72442290(-) A-I      intronic chr3:72442327(-) A-I      intronic chr3:72442435(-) A-I      intronic chr3:72442438(-) A-I      intronic chr3:72442446(-) A-I      intronic chr3:72459179(-) A-I      intronic chr3:72459083(-) A-I      intronic chr3:72465838(-) A-I      intronic chr3:72465843(-) A-I      intronic chr3:72465846(-) A-I      intronic chr3:72465901(-) A-I      intronic chr3:72442421(-) A-I      intronic chr3:72442447(-) A-I      intronic chr3:72489458(-) A-I      intronic chr3:72485250(-) A-I      intronic chr3:72474470(-) A-I      intronic chr3:72465317(-) A-I      intronic chr3:72465852(-) A-I      intronic chr3:72446211(-) A-I      intronic chr3:72442451(-) A-I      intronic chr3:72492483(-) A-I      intronic chr3:72442282(-) A-I      intronic chr3:72484439(-) A-I      intronic chr3:72465837(-) A-I      intronic chr3:72429814(-) A-I      intronic chr3:72442393(-) A-I      intronic chr3:72474486(-) A-I      intronic chr3:72429746(-) A-I      intronic chr3:72442420(-) A-I      intronic chr3:72465861(-) A-I      intronic chr3:72459112(-) A-I      intronic chr3:72465291(-) A-I      intronic chr3:72465223(-) A-I      intronic chr3:72443845(-) A-I      intronic chr3:72429747(-) A-I      intronic chr3:72442450(-) A-I      intronic chr3:72446213(-) A-I      intronic chr3:72485308(-) A-I      intronic chr3:72442504(-) A-I      intronic chr3:72478884(-) A-I      intronic chr3:72465808(-) A-I      intronic chr3:72465879(-) A-I      intronic chr3:72442315(-) A-I      intronic chr3:72469337(-) A-I      intronic chr3:72465242(-) A-I      intronic chr3:72489600(-) A-I      intronic chr3:72476761(-) A-I      intronic chr3:72442311(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RYBP	chr3:72442450(-) A-I intron -    22327324 chr3:72489089(-) A-G intron -    22484847 chr3:72442282(-) A-G intron -    22484847 chr3:72442311(-) A-G intron -    22484847 chr3:72442312(-) A-G intron -    22484847 chr3:72442315(-) A-G intron -    22484847 chr3:72442316(-) A-G intron -    22484847 chr3:72442393(-) A-G intron -    22484847 chr3:72442421(-) A-G intron -    22484847 chr3:72442447(-) A-G intron -    22484847 chr3:72442450(-) A-G intron -    22484847 chr3:72442451(-) A-G intron -    22484847 chr3:72442481(-) A-G intron -    22484847 chr3:72446211(-) A-G intron -    22484847 chr3:72446213(-) A-G intron -    22484847 chr3:72459112(-) A-G intron -    22484847 chr3:72459113(-) A-G intron -    22484847 chr3:72459210(-) A-C intron -    22484847 chr3:72465317(-) A-G intron -    22484847 chr3:72465837(-) A-G intron -    22484847 chr3:72465852(-) A-G intron -    22484847 chr3:72465861(-) A-G intron -    22484847 chr3:72474444(-) T-C intron -    22484847 chr3:72476627(-) G-A intron -    22484847 chr3:72476761(-) A-G intron -    22484847 chr3:72484361(-) A-G intron -    22484847 chr3:72484439(-) A-G intron -    22484847 chr3:72484549(-) A-G intron -    22484847 chr3:72485249(-) A-G intron -    22484847 chr3:72485250(-) A-G intron -    22484847 chr3:72485307(-) A-G intron -    22484847 chr3:72485308(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RYBP	chr3:72423411-72423412(-) m6A 3'UTR       27773535 chr3:72423429-72423430(-) m6A 3'UTR       27773535 chr3:72424984-72424985(-) m6A 3'UTR       - chr3:72425016-72425017(-) m6A 3'UTR       - chr3:72425030-72425031(-) m1A 3'UTR       26863410 chr3:72426790-72426791(-) m6A 3'UTR       24981863//26404942 chr3:72426813-72426814(-) m6A 3'UTR       24981863//26404942//22608085 chr3:72426872-72426873(-) m6A 3'UTR       24981863//22608085 chr3:72427438-72427439(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085 chr3:72427485-72427486(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085 chr3:72427512-72427513(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085 chr3:72427602-72427603(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr3:72427632-72427633(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr3:72427640-72427641(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr3:72427693-72427694(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr3:72427707-72427708(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22608085 chr3:72427767-72427768(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr3:72428206-72428207(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr3:72428215-72428216(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr3:72428247-72428248(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085 chr3:72428405-72428406(-) m6A CDS       24284625//24981863//27773535//27371828//22608085 chr3:72428452-72428453(-) m6A CDS       24981863//27773535//27371828//22608085 chr3:72428463-72428464(-) m6A CDS       24981863//27773535//27371828//22608085 chr3:72428473-72428474(-) m6A CDS       24981863//27773535//27371828//22608085 chr3:72428574-72428575(-) m6A CDS       27773535//27371828 chr3:72495703-72495704(-) m6A CDS       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	RYBP	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US33-5p
Interactor2: RYBP

Evidence Support:

Prediction-Evidence	miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg