Basic Information:

  VIRBase ID:  

VHID00237376

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US33-5p:  MIMAT0001584          PDE5A:  NM_033437     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US33-5p	PDE5A
miRBase Accession/Entrez ID	MIMAT0001584	8654
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CGB-PDE//CN5A//PDE5

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PDE5A	chr4:120459025(-) A-I      intronic chr4:120459033(-) A-I      intronic chr4:120459034(-) A-I      intronic chr4:120459015(-) A-I      intronic chr4:120459050(-) A-I      intronic chr4:120459040(-) A-I      intronic chr4:120459028(-) A-I      intronic chr4:120459017(-) A-I      intronic chr4:120459018(-) A-I      intronic chr4:120459062(-) A-I      intronic chr4:120459077(-) A-I      intronic chr4:120459078(-) A-I      intronic chr4:120509415(-) A-I      intronic chr4:120509387(-) A-I      intronic chr4:120509377(-) A-I      intronic chr4:120459004(-) A-I      intronic chr4:120459010(-) A-I      intronic chr4:120508425(-) A-I      intronic chr4:120508741(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PDE5A	chr4:120423369(-) A-I intron -    22327324 chr4:120423371(-) A-I intron -    22327324 chr4:120458401(-) A-I intron -    22327324

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PDE5A	chr4:120419759-120419760(-) m6A CDS       27773535 chr4:120419809-120419810(-) m6A CDS       27773535 chr4:120419837-120419838(-) m6A CDS       27773535 chr4:120419870-120419871(-) m6A CDS       27773535 chr4:120422382-120422383(-) m6A CDS       24981863 chr4:120422397-120422398(-) m6A CDS       24981863 chr4:120423565-120423566(-) m6A exon//intron       24981863 chr4:120488250-120488251(-) m6A CDS       27773535 chr4:120517721-120517722(-) m6A CDS       27773535 chr4:120527882-120527883(-) m6A CDS       27773535 chr4:120527911-120527912(-) m6A CDS       24284625//27773535//22608085 chr4:120527927-120527928(-) m6A CDS       24284625//27773535//22608085 chr4:120528026-120528027(-) m6A CDS       24284625//24981863//27773535//22608085 chr4:120528070-120528071(-) m6A CDS       24284625//24981863//27773535//22608085 chr4:120528151-120528152(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr4:120528164-120528165(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr4:120528208-120528209(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr4:120528243-120528244(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr4:120528271-120528272(-) m6A CDS       24209618//25456834//24981863//27773535//22608085 chr4:120528318-120528319(-) m6A CDS       25456834//27773535//22608085 chr4:120549159-120549160(-) m6A 5'UTR//intron       25456834 chr4:120549183-120549184(-) m6A 5'UTR//intron       25456834 chr4:120549710-120549711(-) m6A CDS       25456834//24981863//27773536//22608085 chr4:120549743-120549744(-) m6A CDS       25456834//24981863//27773536//22608085 chr4:120549883-120549884(-) m6A 5'UTR       25456834//27773536 chr4:120550010-120550011(-) m6A 5'UTR       27773536 chr4:120550075-120550076(-) m6A 5'UTR       27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PDE5A	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US33-5p
Interactor2: PDE5A

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg