Basic Information:

  VIRBase ID:  

VHID00237362

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US33-5p:  MIMAT0001584          DEGS1:  NM_003676     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US33-5p	DEGS1
miRBase Accession/Entrez ID	MIMAT0001584	8560
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	DEGS//DEGS-1//Des-1//DES1//FADS7//HLD18//MIG15//MLD

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DEGS1	chr1:224375213(+) A-I      intronic chr1:224379052(+) A-I      intronic chr1:224373709(+) A-I      intronic chr1:224378537(+) A-I      intronic chr1:224379521(+) A-I      intronic chr1:224379508(+) A-I      intronic chr1:224379074(+) A-I      intronic chr1:224379012(+) A-I      intronic chr1:224379013(+) A-I      intronic chr1:224379021(+) A-I      intronic chr1:224379062(+) A-I      intronic chr1:224379397(+) A-I      intronic chr1:224373678(+) A-I      intronic chr1:224373821(+) A-I      intronic chr1:224373791(+) A-I      intronic chr1:224374863(+) A-I      intronic chr1:224374174(+) A-I      intronic chr1:224380570(+) A-I      3'UTR chr1:224380522(+) A-I      3'UTR chr1:224375852(+) A-I      intronic chr1:224375821(+) A-I      intronic chr1:224380578(+) A-I      3'UTR chr1:224375732(+) A-I      intronic chr1:224380506(+) A-I      3'UTR chr1:224380501(+) A-I      3'UTR chr1:224375686(+) A-I      intronic chr1:224380579(+) A-I      3'UTR chr1:224380585(+) A-I      3'UTR chr1:224380500(+) A-I      3'UTR chr1:224375682(+) A-I      intronic chr1:224380536(+) A-I      3'UTR chr1:224380609(+) A-I      3'UTR chr1:224375319(+) A-I      intronic chr1:224375309(+) A-I      intronic chr1:224380668(+) A-I      3'UTR chr1:224380712(+) A-I      3'UTR chr1:224380749(+) A-I      3'UTR chr1:224372313(+) A-I      intronic chr1:224379561(+) A-I      intronic chr1:224375295(+) A-I      intronic chr1:224372355(+) A-I      intronic chr1:224372401(+) A-I      intronic chr1:224375291(+) A-I      intronic chr1:224380555(+) A-I      3'UTR chr1:224379499(+) A-I      intronic chr1:224375227(+) A-I      intronic chr1:224379400(+) A-I      intronic chr1:224375226(+) A-I      intronic chr1:224375200(+) A-I      intronic chr1:224380546(+) A-I      3'UTR chr1:224375190(+) A-I      intronic chr1:224379391(+) A-I      intronic chr1:224379361(+) A-I      intronic chr1:224372418(+) A-I      intronic chr1:224379133(+) A-I      intronic chr1:224379042(+) A-I      intronic chr1:224375187(+) A-I      intronic chr1:224380560(+) A-I      3'UTR chr1:224380523(+) A-I      3'UTR chr1:224375186(+) A-I      intronic chr1:224372480(+) A-I      intronic chr1:224375161(+) A-I      intronic chr1:224372494(+) A-I      intronic chr1:224374990(+) A-I      intronic chr1:224378971(+) A-I      intronic chr1:224374962(+) A-I      intronic chr1:224380541(+) A-I      3'UTR chr1:224374912(+) A-I      intronic chr1:224378930(+) A-I      intronic chr1:224374906(+) A-I      intronic chr1:224374895(+) A-I      intronic chr1:224378928(+) A-I      intronic chr1:224374890(+) A-I      intronic chr1:224380569(+) A-I      3'UTR chr1:224373828(+) A-I      intronic chr1:224372582(+) A-I      intronic chr1:224372604(+) A-I      intronic chr1:224374851(+) A-I      intronic chr1:224378904(+) A-I      intronic chr1:224378862(+) A-I      intronic chr1:224374849(+) A-I      intronic chr1:224378857(+) A-I      intronic chr1:224374756(+) A-I      intronic chr1:224374755(+) A-I      intronic chr1:224378851(+) A-I      intronic chr1:224378840(+) A-I      intronic chr1:224378834(+) A-I      intronic chr1:224372630(+) A-I      intronic chr1:224373320(+) A-I      intronic chr1:224378692(+) A-I      intronic chr1:224374268(+) A-I      intronic chr1:224378659(+) A-I      intronic chr1:224378644(+) A-I      intronic chr1:224374258(+) A-I      intronic chr1:224374252(+) A-I      intronic chr1:224374183(+) A-I      intronic chr1:224378607(+) A-I      intronic chr1:224378598(+) A-I      intronic chr1:224373390(+) A-I      intronic chr1:224373647(+) A-I      intronic chr1:224374160(+) A-I      intronic chr1:224373648(+) A-I      intronic chr1:224373653(+) A-I      intronic chr1:224378558(+) A-I      intronic chr1:224378554(+) A-I      intronic chr1:224373906(+) A-I      intronic chr1:224378525(+) A-I      intronic chr1:224373665(+) A-I      intronic chr1:224378524(+) A-I      intronic chr1:224373675(+) A-I      intronic chr1:224373763(+) A-I      intronic chr1:224373766(+) A-I      intronic chr1:224378134(+) A-I      intronic chr1:224373785(+) A-I      intronic chr1:224375930(+) A-I      intronic chr1:224375866(+) A-I      intronic chr1:224378240(+) A-I      intronic chr1:224372314(+) A-I      intronic chr1:224378447(+) A-I      intronic chr1:224372581(+) A-I      intronic chr1:224378177(+) A-I      intronic chr1:224378079(+) A-I      intronic chr1:224378945(+) A-I      intronic chr1:224373056(+) A-I      intronic chr1:224378199(+) A-I      intronic chr1:224373903(+) A-I      intronic chr1:224378566(+) A-I      intronic chr1:224372269(+) A-I      intronic chr1:224378818(+) A-I      intronic chr1:224380498(+) A-I      3'UTR chr1:224378243(+) A-I      intronic chr1:224378189(+) A-I      intronic chr1:224375266(+) A-I      intronic chr1:224378201(+) A-I      intronic chr1:224379501(+) A-I      intronic chr1:224373930(+) A-I      intronic chr1:224372492(+) A-I      intronic chr1:224373057(+) A-I      intronic chr1:224379438(+) A-I      intronic chr1:224378564(+) A-I      intronic chr1:224379144(+) A-I      intronic chr1:224379414(+) A-I      intronic chr1:224379573(+) A-I      intronic chr1:224378091(+) A-I      intronic chr1:224378934(+) A-I      intronic chr1:224378835(+) A-I      intronic chr1:224372655(+) A-I      intronic chr1:224378160(+) A-I      intronic chr1:224373257(+) A-I      intronic chr1:224374308(+) A-I      intronic chr1:224379579(+) A-I      intronic chr1:224375100(+) A-I      intronic chr1:224374916(+) A-I      intronic chr1:224378159(+) A-I      intronic chr1:224372836(+) A-I      intronic chr1:224378161(+) A-I      intronic chr1:224378170(+) A-I      intronic chr1:224379396(+) A-I      intronic chr1:224378908(+) A-I      intronic chr1:224372331(+) A-I      intronic chr1:224378969(+) A-I      intronic chr1:224378880(+) A-I      intronic chr1:224372568(+) A-I      intronic chr1:224374850(+) A-I      intronic chr1:224374795(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	DEGS1	chr1:224373930(+) A-I intron -    22327324 chr1:224375266(+) A-I intron -    21960545 chr1:224375291(+) A-I intron -    21960545 chr1:224375331(+) A-I intron -    21960545 chr1:224378170(+) A-I intron -    21960545

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DEGS1	chr1:224370892-224370893(+) m6A 5'UTR//intron       24209618//25456834//24981863 chr1:224371063-224371064(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr1:224377309-224377310(+) m6A CDS//exon       24284625//24209618//24981863//26404942//22575960//22608085 chr1:224377383-224377384(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:224377389-224377390(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:224377735-224377736(+) m6A CDS//exon       24284625//24209618//24981863//26404942//22608085 chr1:224377876-224377877(+) m6A CDS//exon       24284625//24209618//24981863//26404942//22575960//22608085 chr1:224377919-224377920(+) m6A CDS//exon       24284625//24209618//24981863//26404942//22575960//22608085 chr1:224377978-224377979(+) m6A CDS//exon       24284625//24209618//24981863//26404942//22575960//22608085 chr1:224380213-224380214(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr1:224380249-224380250(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:224380256-224380257(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:224380336-224380337(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:224380379-224380380(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr1:224380556-224380557(+) m6A 3'UTR//intron       24981863 chr1:224380676-224380677(+) m6A 3'UTR       24981863 chr1:224380751-224380752(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	DEGS1	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US33-5p
Interactor2: DEGS1

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg