Basic Information:

  VIRBase ID:  

VHID00236473

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:  MIMAT0001583          TMEM170B:  NM_001100829     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-3p	TMEM170B
miRBase Accession/Entrez ID	MIMAT0001583	100113407
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TMEM170B	chr6:11549623(+) A-I      intronic chr6:11546053(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TMEM170B	chr6:11538598-11538599(+) m6A CDS       24284625 chr6:11575702-11575703(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:11575739-11575740(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:11575829-11575830(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr6:11575896-11575897(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr6:11575922-11575923(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr6:11576019-11576020(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr6:11578673-11578674(+) m6A 3'UTR       24981863//22608085 chr6:11578688-11578689(+) m6A 3'UTR       24981863//22608085 chr6:11578741-11578742(+) m6A 3'UTR       24981863//22608085 chr6:11578760-11578761(+) m6A 3'UTR       22608085 chr6:11578777-11578778(+) m6A 3'UTR       22608085 chr6:11578793-11578794(+) m6A 3'UTR       22608085 chr6:11578801-11578802(+) m6A 3'UTR       22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	TMEM170B	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US25-2-3p	Irinotecan       60838

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-3p
Interactor2: TMEM170B

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg