Basic Information:

  VIRBase ID:  

VHID00236059

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:  MIMAT0001583          RAB12:  NM_001025300     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-3p	RAB12
miRBase Accession/Entrez ID	MIMAT0001583	201475
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RAB12	chr18:8632185(+) A-I      intronic chr18:8632047(+) A-I      intronic chr18:8619887(+) A-I      intronic chr18:8618637(+) A-I      intronic chr18:8614714(+) A-I      intronic chr18:8614764(+) A-I      intronic chr18:8630961(+) A-I      intronic chr18:8614710(+) A-I      intronic chr18:8632161(+) A-I      intronic chr18:8618561(+) A-I      intronic chr18:8632182(+) A-I      intronic chr18:8631088(+) A-I      intronic chr18:8632046(+) A-I      intronic chr18:8619951(+) A-I      intronic chr18:8614850(+) A-I      intronic chr18:8619953(+) A-I      intronic chr18:8614683(+) A-I      intronic chr18:8620011(+) A-I      intronic chr18:8619985(+) A-I      intronic chr18:8632196(+) A-I      intronic chr18:8616780(+) A-I      intronic chr18:8619949(+) A-I      intronic chr18:8618625(+) A-I      intronic chr18:8631067(+) A-I      intronic chr18:8614608(+) A-I      intronic chr18:8618588(+) A-I      intronic chr18:8614684(+) A-I      intronic chr18:8632197(+) A-I      intronic chr18:8632011(+) A-I      intronic chr18:8616829(+) A-I      intronic chr18:8631026(+) A-I      intronic chr18:8632102(+) A-I      intronic chr18:8619889(+) A-I      intronic chr18:8632133(+) A-I      intronic chr18:8632051(+) A-I      intronic chr18:8614701(+) A-I      intronic chr18:8618695(+) A-I      intronic chr18:8620113(+) A-I      intronic chr18:8619871(+) A-I      intronic chr18:8631135(+) A-I      intronic chr18:8616909(+) A-I      intronic chr18:8631085(+) A-I      intronic chr18:8614614(+) A-I      intronic chr18:8616911(+) A-I      intronic chr18:8614687(+) A-I      intronic chr18:8619888(+) A-I      intronic chr18:8632018(+) A-I      intronic chr18:8631070(+) A-I      intronic chr18:8616816(+) A-I      intronic chr18:8630986(+) A-I      intronic chr18:8618717(+) A-I      intronic chr18:8616812(+) A-I      intronic chr18:8630980(+) A-I      intronic chr18:8619964(+) A-I      intronic chr18:8620051(+) A-I      intronic chr18:8614773(+) A-I      intronic chr18:8616851(+) A-I      intronic chr18:8632129(+) A-I      intronic chr18:8630967(+) A-I      intronic chr18:8632296(+) A-I      intronic chr18:8619893(+) A-I      intronic chr18:8632084(+) A-I      intronic chr18:8631048(+) A-I      intronic chr18:8632104(+) A-I      intronic chr18:8614767(+) A-I      intronic chr18:8630990(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RAB12	chr18:8614683(+) A-I intron -    21960545 chr18:8614684(+) A-I intron -    21960545 chr18:8616816(+) A-G intron -    22484847 chr18:8616847(+) A-G intron -    22484847 chr18:8616911(+) A-G intron -    22484847 chr18:8619885(+) A-G intron -    22484847 chr18:8619964(+) A-G intron -    22484847 chr18:8620011(+) A-G intron -    22484847 chr18:8631026(+) A-G intron -    22484847 chr18:8632011(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RAB12	chr18:8609525-8609526(+) m6A 5'UTR       24209618 chr18:8609890-8609891(+) m6A CDS       24209618 chr18:8633283-8633284(+) m6A CDS//exon       27773535 chr18:8635576-8635577(+) m6A CDS       24981863//27773535 chr18:8635588-8635589(+) m6A CDS       24981863//27773535 chr18:8638956-8638957(+) m6A 3'UTR       27773535 chr18:8638977-8638978(+) m6A 3'UTR       27773535 chr18:8638994-8638995(+) m6A 3'UTR       27773535 chr18:8639046-8639047(+) m6A 3'UTR       27773535 chr18:8639143-8639144(+) Y 3'UTR       26075521

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	RAB12	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US25-2-3p	Irinotecan       60838

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-3p
Interactor2: RAB12

Evidence Support:

Prediction-Evidence	miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg