Basic Information:

  VIRBase ID:  

VHID00235658

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:  MIMAT0001583          CYP2U1:  NM_183075     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-3p	CYP2U1
miRBase Accession/Entrez ID	MIMAT0001583	113612
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	P450TEC//SPG49//SPG56

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CYP2U1	chr4:108861353(+) A-I      intronic chr4:108860242(+) A-I      intronic chr4:108860064(+) A-I      intronic chr4:108861315(+) A-I      intronic chr4:108861348(+) A-I      intronic chr4:108861329(+) A-I      intronic chr4:108861310(+) A-I      intronic chr4:108861305(+) A-I      intronic chr4:108865478(+) A-I      intronic chr4:108865599(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CYP2U1	chr4:108852717-108852718(+) m6A 5'UTR       24981863 chr4:108852774-108852775(+) m6A 5'UTR//exon       24981863 chr4:108852796-108852797(+) m6A 5'UTR//exon       24981863 chr4:108852836-108852837(+) m6A 5'UTR//CDS//exon       - chr4:108866281-108866282(+) m6A CDS       22608085 chr4:108866425-108866426(+) m6A CDS       24284625//24981863//22608085 chr4:108866480-108866481(+) m6A CDS       24284625//24981863//22608085 chr4:108866498-108866499(+) m6A CDS       24284625//24981863//22608085 chr4:108866545-108866546(+) m6A CDS       24284625//24981863//22608085 chr4:108866572-108866573(+) m6A CDS       24284625//24981863//22608085 chr4:108866581-108866582(+) m6A CDS       24284625//24981863//22608085 chr4:108866590-108866591(+) m6A CDS       24284625//24981863//22608085 chr4:108866694-108866695(+) m6A CDS       24284625//24981863//22608085 chr4:108866746-108866747(+) m6A CDS       24284625//24981863//22608085 chr4:108868591-108868592(+) m6A CDS       24284625//22608085 chr4:108871422-108871423(+) m6A CDS       24981863//22608085 chr4:108871656-108871657(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr4:108871805-108871806(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr4:108871892-108871893(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr4:108871922-108871923(+) m6A 3'UTR       24284625//24981863//22608085 chr4:108872015-108872016(+) m6A 3'UTR       24284625//24981863//22608085 chr4:108872053-108872054(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr4:108872134-108872135(+) m6A 3'UTR       24981863//22608085 chr4:108872240-108872241(+) m6A 3'UTR       22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CYP2U1	Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US25-2-3p	Irinotecan       60838

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-3p
Interactor2: CYP2U1

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg