Basic Information:

  VIRBase ID:  

VHID00235469

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:  MIMAT0001583          MEGF10:  NM_032446     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-3p	MEGF10
miRBase Accession/Entrez ID	MIMAT0001583	84466
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	EMARDD//SR-F3

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MEGF10	chr5:126721666(+) A-I      intronic chr5:126751474(+) A-I      intronic chr5:126744514(+) A-I      intronic chr5:126751475(+) A-I      intronic chr5:126638864(+) A-I      intronic chr5:126751338(+) A-I      intronic chr5:126724046(+) A-I      intronic chr5:126744513(+) A-I      intronic chr5:126721226(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MEGF10	chr5:126758399(+) A-I exon CDS    19478186

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MEGF10	chr5:126626608-126626609(+) m6A 5'UTR       24209618 chr5:126626666-126626667(+) m6A 5'UTR       24209618 chr5:126760334-126760335(+) m6A 3'UTR//intron       24209618//25456834 chr5:126760357-126760358(+) m6A 3'UTR//intron       24209618//25456834 chr5:126760390-126760391(+) m6A 3'UTR//intron       24209618 chr5:126760434-126760435(+) m6A 3'UTR//intron       24209618 chr5:126792897-126792898(+) m6A CDS//intron       25456834//24981863 chr5:126792939-126792940(+) m6A CDS//intron       25456834//24981863 chr5:126792966-126792967(+) m6A CDS//intron       25456834//24981863 chr5:126793019-126793020(+) m6A 3'UTR//intron       25456834//24981863//22608085 chr5:126793039-126793040(+) m6A 3'UTR//intron       25456834//24981863//22608085 chr5:126793051-126793052(+) m6A 3'UTR//intron       25456834//24981863//22608085 chr5:126793129-126793130(+) m6A 3'UTR//intron       24209618//25456834//24981863//22608085 chr5:126793135-126793136(+) m6A 3'UTR//intron       24209618//25456834//24981863//22608085 chr5:126793166-126793167(+) m6A 3'UTR//intron       24209618//25456834//24981863//22608085 chr5:126793239-126793240(+) m6A 3'UTR//intron       24209618//25456834//24981863//22608085 chr5:126793289-126793290(+) m6A 3'UTR//intron       24209618//25456834//24981863//22608085 chr5:126793298-126793299(+) m6A 3'UTR//intron       24209618//25456834//24981863//22608085 chr5:126793326-126793327(+) m6A 3'UTR//intron       24209618//25456834//24981863 chr5:126793450-126793451(+) m6A 3'UTR//intron       24209618//24981863 chr5:126793461-126793462(+) m6A 3'UTR//intron       24209618//24981863 chr5:126793468-126793469(+) m6A 3'UTR//intron       24209618//24981863 chr5:126793508-126793509(+) m6A 3'UTR//intron       24981863 chr5:126793545-126793546(+) m6A 3'UTR//intron       24981863 chr5:126793570-126793571(+) m6A 3'UTR//intron       24981863 chr5:126793598-126793599(+) m6A 3'UTR//intron       24981863 chr5:126796898-126796899(+) m6A 3'UTR//intron       25456834 chr5:126801302-126801303(+) m6A exon       25456834 chr5:126801307-126801308(+) m6A exon       25456834 chr5:126801313-126801314(+) m6A exon       25456834 chr5:126801340-126801341(+) m6A exon       25456834 chr5:126801353-126801354(+) m6A exon       25456834 chr5:126801382-126801383(+) m6A exon       25456834 chr5:126801391-126801392(+) m6A exon       25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MEGF10	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US25-2-3p	Irinotecan       60838

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-3p
Interactor2: MEGF10

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg