Basic Information:

  VIRBase ID:  

VHID00235271

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:  MIMAT0001583          ZNF672:  NM_024836     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-3p	ZNF672
miRBase Accession/Entrez ID	MIMAT0001583	79894
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ZNF672	chr1:249135768(+) A-I      intronic chr1:249136184(+) A-I      intronic chr1:249136185(+) A-I      intronic chr1:249136551(+) A-I      intronic chr1:249136186(+) A-I      intronic chr1:249133712(+) A-I      intronic chr1:249133768(+) A-I      intronic chr1:249133824(+) A-I      intronic chr1:249133826(+) A-I      intronic chr1:249134429(+) A-I      intronic chr1:249139215(+) A-I      intronic chr1:249133815(+) A-I      intronic chr1:249136629(+) A-I      intronic chr1:249136475(+) A-I      intronic chr1:249136453(+) A-I      intronic chr1:249133631(+) A-I      intronic chr1:249135536(+) A-I      intronic chr1:249136495(+) A-I      intronic chr1:249139212(+) A-I      intronic chr1:249135663(+) A-I      intronic chr1:249134369(+) A-I      intronic chr1:249135662(+) A-I      intronic chr1:249133600(+) A-I      intronic chr1:249133630(+) A-I      intronic chr1:249135657(+) A-I      intronic chr1:249133656(+) A-I      intronic chr1:249135718(+) A-I      intronic chr1:249134389(+) A-I      intronic chr1:249136585(+) A-I      intronic chr1:249133763(+) A-I      intronic chr1:249133830(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ZNF672	chr1:249136475(+) A-I intron -    22327324 chr1:249136629(+) A-I intron -    22327324 chr1:249135718(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ZNF672	chr1:249132531-249132532(+) m6A 5'UTR//exon       24284625//25456834//24981863 chr1:249132561-249132562(+) m6A 5'UTR//exon       24284625//25456834//24981863 chr1:249132716-249132717(+) m6A 5'UTR//intron       27371828//22575960 chr1:249138772-249138773(+) m6A 5'UTR//exon       24284625 chr1:249138785-249138786(+) m6A 5'UTR//exon       24284625 chr1:249139794-249139795(+) m6A 5'UTR//exon       24284625 chr1:249139853-249139854(+) m6A 5'UTR//exon       24284625 chr1:249141268-249141269(+) m6A 5'UTR//exon//intron       24284625 chr1:249141291-249141292(+) m6A 5'UTR//exon//intron       24284625 chr1:249141321-249141322(+) m6A 5'UTR//exon//intron       24284625//22608085 chr1:249141334-249141335(+) m6A 5'UTR//exon//intron       24284625//24981863//22608085 chr1:249141402-249141403(+) m6A 5'UTR//exon       24284625//25456834//24981863//22575960//22608085 chr1:249141427-249141428(+) m6A 5'UTR       24284625//25456834//24981863//22575960//22608085 chr1:249141460-249141461(+) m6A 5'UTR       24284625//25456834//24981863//22575960//22608085 chr1:249141674-249141675(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr1:249141700-249141701(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr1:249141932-249141933(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr1:249142147-249142148(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr1:249142446-249142447(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:249142498-249142499(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:249142801-249142802(+) m6A CDS       24284625//24981863 chr1:249142897-249142898(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr1:249143507-249143508(+) m6A 3'UTR       24284625 chr1:249143531-249143532(+) m6A 3'UTR       24284625//24981863 chr1:249143546-249143547(+) m6A 3'UTR       24284625//24981863//22608085 chr1:249143558-249143559(+) m6A 3'UTR       24284625//24981863//22608085 chr1:249143596-249143597(+) m6A 3'UTR       24284625//25456834//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ZNF672	Cytosol HeLa-S3 cells|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US25-2-3p	Irinotecan       60838

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-3p
Interactor2: ZNF672

Evidence Support:

Prediction-Evidence	miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg