Basic Information:

  VIRBase ID:  

VHID00234728

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:  MIMAT0001583          TMEM63B:  NM_018426     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-3p	TMEM63B
miRBase Accession/Entrez ID	MIMAT0001583	55362
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	C6orf110

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TMEM63B	chr6:44098784(+) A-I      intronic chr6:44098794(+) A-I      intronic chr6:44099401(+) A-I      intronic chr6:44099381(+) A-I      intronic chr6:44099368(+) A-I      intronic chr6:44115830(+) A-I      intronic chr6:44098343(+) A-I      intronic chr6:44098723(+) A-I      intronic chr6:44098724(+) A-I      intronic chr6:44115632(+) A-I      intronic chr6:44115614(+) A-I      intronic chr6:44098462(+) A-I      intronic chr6:44114484(+) A-I      intronic chr6:44114327(+) A-I      intronic chr6:44113286(+) A-I      intronic chr6:44113209(+) A-I      intronic chr6:44112938(+) A-I      intronic chr6:44112897(+) A-I      intronic chr6:44112759(+) A-I      intronic chr6:44112518(+) A-I      intronic chr6:44112479(+) A-I      intronic chr6:44112433(+) A-I      intronic chr6:44112413(+) A-I      intronic chr6:44099309(+) A-I      intronic chr6:44113232(+) A-I      intronic chr6:44112351(+) A-I      intronic chr6:44114449(+) A-I      intronic chr6:44112609(+) A-I      intronic chr6:44098582(+) A-I      intronic chr6:44098754(+) A-I      intronic chr6:44098894(+) A-I      intronic chr6:44115695(+) A-I      intronic chr6:44112345(+) A-I      intronic chr6:44112420(+) A-I      intronic chr6:44105459(+) A-I      intronic chr6:44112463(+) A-I      intronic chr6:44112892(+) A-I      intronic chr6:44097025(+) A-I      intronic chr6:44096847(+) A-I      intronic chr6:44113263(+) A-I      intronic chr6:44105562(+) A-I      intronic chr6:44112891(+) A-I      intronic chr6:44098398(+) A-I      intronic chr6:44113284(+) A-I      intronic chr6:44112597(+) A-I      intronic chr6:44112403(+) A-I      intronic chr6:44099367(+) A-I      intronic chr6:44098929(+) A-I      intronic chr6:44098294(+) A-I      intronic chr6:44110674(+) A-I      intronic chr6:44110120(+) A-I      intronic chr6:44109748(+) A-I      intronic chr6:44099437(+) A-I      intronic chr6:44113444(+) A-I      intronic chr6:44104752(+) A-I      intronic chr6:44098917(+) A-I      intronic chr6:44112475(+) A-I      intronic chr6:44110146(+) A-I      intronic chr6:44110641(+) A-I      intronic chr6:44109738(+) A-I      intronic chr6:44113222(+) A-I      intronic chr6:44105697(+) A-I      intronic chr6:44110082(+) A-I      intronic chr6:44113208(+) A-I      intronic chr6:44098276(+) A-I      intronic chr6:44098250(+) A-I      intronic chr6:44114450(+) A-I      intronic chr6:44113258(+) A-I      intronic chr6:44098840(+) A-I      intronic chr6:44099300(+) A-I      intronic chr6:44112587(+) A-I      intronic chr6:44098316(+) A-I      intronic chr6:44098866(+) A-I      intronic chr6:44112544(+) A-I      intronic chr6:44105637(+) A-I      intronic chr6:44110046(+) A-I      intronic chr6:44104595(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TMEM63B	chr6:44112892(+) A-I intron -    22327324 chr6:44098250(+) A-G intron -    22484847 chr6:44098316(+) A-G intron -    22484847 chr6:44098686(+) A-G intron -    22484847 chr6:44098754(+) A-G intron -    22484847 chr6:44098755(+) A-G intron -    22484847 chr6:44098796(+) A-G intron -    22484847 chr6:44099247(+) A-G intron -    22484847 chr6:44099300(+) A-G intron -    22484847 chr6:44099345(+) A-G intron -    22484847 chr6:44099349(+) A-G intron -    22484847 chr6:44099377(+) A-G intron -    22484847 chr6:44099437(+) A-G intron -    22484847 chr6:44112345(+) A-G intron -    22484847 chr6:44112347(+) A-G intron -    22484847 chr6:44112349(+) A-G intron -    22484847 chr6:44112351(+) A-G intron -    22484847 chr6:44112357(+) A-G intron -    22484847 chr6:44112473(+) A-G intron -    22484847 chr6:44112475(+) A-G intron -    22484847 chr6:44112524(+) A-G intron -    22484847 chr6:44112544(+) A-G intron -    22484847 chr6:44112587(+) A-G intron -    22484847 chr6:44112892(+) A-G intron -    22484847 chr6:44113208(+) A-G intron -    22484847 chr6:44113222(+) A-G intron -    22484847 chr6:44113258(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TMEM63B	chr6:44094682-44094683(+) m6A 5'UTR       - chr6:44095483-44095484(+) m6A exon//intron       24284625 chr6:44095489-44095490(+) m6A exon//intron       24284625 chr6:44095527-44095528(+) m6A exon//intron       24284625 chr6:44095552-44095553(+) m6A exon//intron       24284625 chr6:44108773-44108774(+) m6A 3'UTR//CDS//exon       - chr6:44115148-44115149(+) m6A 3'UTR//CDS//exon       - chr6:44116037-44116038(+) m6A 3'UTR//CDS//exon       24284625 chr6:44116108-44116109(+) m6A 3'UTR//CDS//exon       24284625 chr6:44116260-44116261(+) m6A 3'UTR//CDS//exon       24284625 chr6:44116349-44116350(+) m6A 3'UTR//CDS//exon       24284625 chr6:44116377-44116378(+) m6A CDS//exon       24284625 chr6:44116644-44116645(+) m6A CDS//exon       24284625//24981863 chr6:44116816-44116817(+) m6A exon//intron       - chr6:44122453-44122454(+) m6A 3'UTR//CDS       24981863 chr6:44122564-44122565(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085 chr6:44122570-44122571(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//22608085 chr6:44122588-44122589(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//22608085 chr6:44122677-44122678(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr6:44122751-44122752(+) m6A 3'UTR       24981863//26404942 chr6:44122965-44122966(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	TMEM63B	Chromatin K562 cells     - Cytosol K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US25-2-3p	Irinotecan       60838

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-3p
Interactor2: TMEM63B

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg