Basic Information:

  VIRBase ID:  

VHID00234726

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:  MIMAT0001583          LAPTM4B:  NM_018407     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-3p	LAPTM4B
miRBase Accession/Entrez ID	MIMAT0001583	55353
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	LAPTM4beta//LC27

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	LAPTM4B	chr8:98855211(+) A-I      intronic chr8:98813476(+) A-I      intronic chr8:98807895(+) A-I      intronic chr8:98807894(+) A-I      intronic chr8:98833096(+) A-I      intronic chr8:98851453(+) A-I      intronic chr8:98855193(+) A-I      intronic chr8:98855207(+) A-I      intronic chr8:98855210(+) A-I      intronic chr8:98821817(+) A-I      intronic chr8:98858625(+) A-I      intronic chr8:98860370(+) A-I      intronic chr8:98855299(+) A-I      intronic chr8:98858741(+) A-I      intronic chr8:98858659(+) A-I      intronic chr8:98858735(+) A-I      intronic chr8:98807130(+) A-I      intronic chr8:98860245(+) A-I      intronic chr8:98860801(+) A-I      intronic chr8:98860282(+) A-I      intronic chr8:98860340(+) A-I      intronic chr8:98860343(+) A-I      intronic chr8:98860296(+) A-I      intronic chr8:98860316(+) A-I      intronic chr8:98860336(+) A-I      intronic chr8:98860353(+) A-I      intronic chr8:98860369(+) A-I      intronic chr8:98860816(+) A-I      intronic chr8:98815174(+) A-I      intronic chr8:98860839(+) A-I      intronic chr8:98820283(+) A-I      intronic chr8:98812944(+) A-I      intronic chr8:98820292(+) A-I      intronic chr8:98853739(+) A-I      intronic chr8:98854864(+) A-I      intronic chr8:98821808(+) A-I      intronic chr8:98821813(+) A-I      intronic chr8:98860809(+) A-I      intronic chr8:98798734(+) A-I      intronic chr8:98794338(+) A-I      intronic chr8:98791906(+) A-I      intronic chr8:98791848(+) A-I      intronic chr8:98791459(+) A-I      intronic chr8:98860852(+) A-I      intronic chr8:98821824(+) A-I      intronic chr8:98860838(+) A-I      intronic chr8:98820249(+) A-I      intronic chr8:98826537(+) A-I      intronic chr8:98829013(+) A-I      intronic chr8:98829123(+) A-I      intronic chr8:98832818(+) A-I      intronic chr8:98832864(+) A-I      intronic chr8:98858742(+) A-I      intronic chr8:98858760(+) A-I      intronic chr8:98813993(+) A-I      intronic chr8:98813571(+) A-I      intronic chr8:98864016(+) A-I      3'UTR chr8:98864017(+) A-I      3'UTR chr8:98863988(+) A-I      3'UTR chr8:98863960(+) A-I      3'UTR chr8:98863959(+) A-I      3'UTR chr8:98820284(+) A-I      intronic chr8:98826483(+) A-I      intronic chr8:98791540(+) A-I      intronic chr8:98795086(+) A-I      intronic chr8:98822370(+) A-I      intronic chr8:98832871(+) A-I      intronic chr8:98821659(+) A-I      intronic chr8:98855940(+) A-I      intronic chr8:98813671(+) A-I      intronic chr8:98827048(+) A-I      intronic chr8:98833443(+) A-I      intronic chr8:98791541(+) A-I      intronic chr8:98795089(+) A-I      intronic chr8:98827051(+) A-I      intronic chr8:98793645(+) A-I      intronic chr8:98822418(+) A-I      intronic chr8:98822222(+) A-I      intronic chr8:98860315(+) A-I      intronic chr8:98860234(+) A-I      intronic chr8:98860305(+) A-I      intronic chr8:98855897(+) A-I      intronic chr8:98798748(+) A-I      intronic chr8:98821110(+) A-I      intronic chr8:98846881(+) A-I      intronic chr8:98826627(+) A-I      intronic chr8:98832881(+) A-I      intronic chr8:98791454(+) A-I      intronic chr8:98796873(+) A-I      intronic chr8:98855774(+) A-I      intronic chr8:98792552(+) A-I      intronic chr8:98816362(+) A-I      intronic chr8:98855751(+) A-I      intronic chr8:98833086(+) A-I      intronic chr8:98835170(+) A-I      intronic chr8:98855933(+) A-I      intronic chr8:98813678(+) A-I      intronic chr8:98855964(+) A-I      intronic chr8:98855246(+) A-I      intronic chr8:98846351(+) A-I      intronic chr8:98820543(+) A-I      intronic chr8:98855298(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	LAPTM4B	chr8:98806169(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	LAPTM4B	chr8:98787796-98787797(+) m6A 5'UTR       25456834 chr8:98787801-98787802(+) m6A 5'UTR       25456834 chr8:98787866-98787867(+) m6A 5'UTR       25456834 chr8:98787891-98787892(+) m6A 5'UTR       25456834 chr8:98787976-98787977(+) m6A CDS       25456834//24981863 chr8:98788086-98788087(+) Y 5'UTR//CDS       26075521 chr8:98788201-98788202(+) m6A 5'UTR//CDS       24209618//27773536//22575960 chr8:98788265-98788266(+) Y CDS       26075521 chr8:98863878-98863879(+) m6A 3'UTR       27773535 chr8:98863960-98863961(+) m6A 3'UTR       27773535 chr8:98863980-98863981(+) m6A 3'UTR       27773535 chr8:98864066-98864067(+) m6A 3'UTR       27773535 chr8:98864077-98864078(+) m6A 3'UTR       27773535 chr8:98864354-98864355(+) m6A 3'UTR       22575960 chr8:98864648-98864649(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	LAPTM4B	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US25-2-3p	Irinotecan       60838

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-3p
Interactor2: LAPTM4B

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg