Basic Information:

  VIRBase ID:  

VHID00234699

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:  MIMAT0001583          UBA6:  NM_018227     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-3p	UBA6
miRBase Accession/Entrez ID	MIMAT0001583	55236
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	E1-L2//MOP-4//UBE1L2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	UBA6	chr4:68513525(-) A-I      intronic chr4:68564578(-) A-I      intronic chr4:68564421(-) A-I      intronic chr4:68549663(-) A-I      intronic chr4:68564621(-) A-I      intronic chr4:68541362(-) A-I      intronic chr4:68564673(-) A-I      intronic chr4:68514022(-) A-I      intronic chr4:68565613(-) A-I      intronic chr4:68514074(-) A-I      intronic chr4:68552523(-) A-I      intronic chr4:68541354(-) A-I      intronic chr4:68532401(-) A-I      intronic chr4:68513943(-) A-I      intronic chr4:68513041(-) A-I      intronic chr4:68565571(-) A-I      intronic chr4:68513564(-) A-I      intronic chr4:68513624(-) A-I      intronic chr4:68513648(-) A-I      intronic chr4:68513661(-) A-I      intronic chr4:68513663(-) A-I      intronic chr4:68513669(-) A-I      intronic chr4:68513675(-) A-I      intronic chr4:68513709(-) A-I      intronic chr4:68513712(-) A-I      intronic chr4:68513728(-) A-I      intronic chr4:68513733(-) A-I      intronic chr4:68513961(-) A-I      intronic chr4:68562791(-) A-I      intronic chr4:68514056(-) A-I      intronic chr4:68514062(-) A-I      intronic chr4:68514184(-) A-I      intronic chr4:68538965(-) A-I      intronic chr4:68541269(-) A-I      intronic chr4:68541283(-) A-I      intronic chr4:68552548(-) A-I      intronic chr4:68552572(-) A-I      intronic chr4:68552589(-) A-I      intronic chr4:68559728(-) A-I      intronic chr4:68559847(-) A-I      intronic chr4:68559851(-) A-I      intronic chr4:68560404(-) A-I      intronic chr4:68562797(-) A-I      intronic chr4:68564566(-) A-I      intronic chr4:68540684(-) A-I      intronic chr4:68564671(-) A-I      intronic chr4:68541776(-) A-I      intronic chr4:68513597(-) A-I      intronic chr4:68540685(-) A-I      intronic chr4:68552485(-) A-I      intronic chr4:68513670(-) A-I      intronic chr4:68513659(-) A-I      intronic chr4:68513711(-) A-I      intronic chr4:68540834(-) A-I      intronic chr4:68540758(-) A-I      intronic chr4:68552556(-) A-I      intronic chr4:68513981(-) A-I      intronic chr4:68487381(-) A-I      intronic chr4:68512949(-) A-I      intronic chr4:68512919(-) A-I      intronic chr4:68540820(-) A-I      intronic chr4:68514054(-) A-I      intronic chr4:68513942(-) A-I      intronic chr4:68541232(-) A-I      intronic chr4:68513982(-) A-I      intronic chr4:68513521(-) A-I      intronic chr4:68513764(-) A-I      intronic chr4:68513072(-) A-I      intronic chr4:68514164(-) A-I      intronic chr4:68513002(-) A-I      intronic chr4:68564642(-) A-I      intronic chr4:68514172(-) A-I      intronic chr4:68513082(-) A-I      intronic chr4:68552586(-) A-I      intronic chr4:68552620(-) A-I      intronic chr4:68514017(-) A-I      intronic chr4:68535886(-) A-I      intronic chr4:68514123(-) A-I      intronic chr4:68541183(-) A-I      intronic chr4:68514019(-) A-I      intronic chr4:68514134(-) A-I      intronic chr4:68513993(-) A-I      intronic chr4:68513630(-) A-I      intronic chr4:68513660(-) A-I      intronic chr4:68560170(-) A-I      intronic chr4:68541192(-) A-I      intronic chr4:68552892(-) A-I      intronic chr4:68541769(-) A-I      intronic chr4:68513137(-) A-I      intronic chr4:68513763(-) A-I      intronic chr4:68560238(-) A-I      intronic chr4:68552550(-) A-I      intronic chr4:68513134(-) A-I      intronic chr4:68513581(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	UBA6	chr4:68491519(-) A-I intron -    21960545 chr4:68487381(-) A-G intron -    22484847 chr4:68512919(-) A-G intron -    22484847 chr4:68512986(-) A-G intron -    22484847 chr4:68513000(-) A-G intron -    22484847 chr4:68513002(-) A-G intron -    22484847 chr4:68513072(-) A-G intron -    22484847 chr4:68513557(-) A-G intron -    22484847 chr4:68513597(-) A-G intron -    22484847 chr4:68513659(-) A-G intron -    22484847 chr4:68513660(-) A-G intron -    22484847 chr4:68513670(-) A-G intron -    22484847 chr4:68513672(-) A-G intron -    22484847 chr4:68513711(-) A-G intron -    22484847 chr4:68513749(-) A-G intron -    22484847 chr4:68514017(-) A-G intron -    22484847 chr4:68514019(-) A-G intron -    22484847 chr4:68514054(-) A-G intron -    22484847 chr4:68514077(-) A-G intron -    22484847 chr4:68514078(-) A-G intron -    22484847 chr4:68514086(-) A-G intron -    22484847 chr4:68514134(-) A-G intron -    22484847 chr4:68514147(-) A-G intron -    22484847 chr4:68514172(-) A-G intron -    22484847 chr4:68514201(-) A-T intron -    22484847 chr4:68514203(-) T-A intron -    22484847 chr4:68528430(-) A-G intron -    22484847 chr4:68552485(-) A-G intron -    22484847 chr4:68552550(-) A-G intron -    22484847 chr4:68552556(-) A-G intron -    22484847 chr4:68552586(-) A-G intron -    22484847 chr4:68552892(-) A-G intron -    22484847 chr4:68564642(-) A-G intron -    22484847 chr4:68564671(-) A-G intron -    22484847 chr4:68565364(-) T-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	UBA6	chr4:68478725-68478726(-) m6A 3'UTR       27773535 chr4:68479752-68479753(-) m6A 3'UTR       27773535 chr4:68479790-68479791(-) m6A 3'UTR       27773535 chr4:68479801-68479802(-) m6A 3'UTR       27773535 chr4:68480057-68480058(-) m6A 3'UTR       - chr4:68480608-68480609(-) m6A 3'UTR       27773535 chr4:68480801-68480802(-) m6A 3'UTR       27773535//22608085 chr4:68480813-68480814(-) m6A 3'UTR       27773535//22608085 chr4:68480877-68480878(-) m6A 3'UTR       25456834//27773535//22608085 chr4:68480944-68480945(-) m6A 3'UTR       24981863//27773535//27371828//22608085 chr4:68481040-68481041(-) m6A 3'UTR       24981863//27773535//22608085 chr4:68481086-68481087(-) m6A 3'UTR       24981863//27773535//22608085 chr4:68481145-68481146(-) m6A 3'UTR       24981863//27773535//22608085 chr4:68483011-68483012(-) m6A 3'UTR       24981863 chr4:68483023-68483024(-) m6A 3'UTR       24981863 chr4:68483796-68483797(-) m6A 3'UTR       27773535 chr4:68483889-68483890(-) m6A 3'UTR       27773535 chr4:68483912-68483913(-) m6A 3'UTR       27773535//22608085 chr4:68483919-68483920(-) m6A 3'UTR       27773535//22608085 chr4:68483988-68483989(-) m6A 3'UTR       24284625//25456834//24981863//26404942//27773535//22608085 chr4:68484024-68484025(-) m6A 3'UTR       24284625//25456834//24981863//28052920//26404942//27773535//22608085 chr4:68484038-68484039(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//22608085 chr4:68484049-68484050(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//22608085 chr4:68484063-68484064(-) m6A 3'UTR       24284625//24209618//24981863//28052920//26404942//27773535//22608085 chr4:68484308-68484309(-) m6A 3'UTR       24284625//24209618//24981863//28052920//27773535//22608085 chr4:68484396-68484397(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr4:68484484-68484485(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr4:68484551-68484552(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr4:68484572-68484573(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr4:68484585-68484586(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr4:68484686-68484687(-) m6A 3'UTR       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr4:68484753-68484754(-) m6A 3'UTR//CDS       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085 chr4:68484781-68484782(-) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085 chr4:68484831-68484832(-) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr4:68484840-68484841(-) m6A 3'UTR//CDS       24284625//24209618//27773535//22608085 chr4:68504716-68504717(-) m6A CDS       26404942 chr4:68504745-68504746(-) m6A CDS       26404942 chr4:68504787-68504788(-) Am CDS       - chr4:68566773-68566774(-) m6A CDS//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	UBA6	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome HEK-293 cells     22199352

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US25-2-3p	Irinotecan       60838

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-3p
Interactor2: UBA6

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg