Basic Information:

  VIRBase ID:  

VHID00234588

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:  MIMAT0001583          CRLS1:  NR_136617     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-3p	CRLS1
miRBase Accession/Entrez ID	MIMAT0001583	54675
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	C20orf155//CLS//CLS1//dJ967N21.6//GCD10

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CRLS1	chr20:5998609(+) A-I      intronic chr20:5998644(+) A-I      intronic chr20:5998751(+) A-I      intronic chr20:5998755(+) A-I      intronic chr20:6018431(+) A-I      3'UTR chr20:6018432(+) A-I      3'UTR chr20:6018404(+) A-I      3'UTR chr20:6018372(+) A-I      3'UTR chr20:6018382(+) A-I      3'UTR chr20:6018460(+) A-I      3'UTR chr20:6018464(+) A-I      3'UTR chr20:6010125(+) A-I      intronic chr20:6018473(+) A-I      3'UTR chr20:6018479(+) A-I      3'UTR chr20:5998774(+) A-I      intronic chr20:5998782(+) A-I      intronic chr20:5998790(+) A-I      intronic chr20:5998822(+) A-I      intronic chr20:6018363(+) A-I      3'UTR chr20:6018506(+) A-I      3'UTR chr20:5998819(+) A-I      intronic chr20:6018504(+) A-I      3'UTR chr20:6001817(+) A-I      intronic chr20:6001825(+) A-I      intronic chr20:6001830(+) A-I      intronic chr20:6001842(+) A-I      intronic chr20:6010133(+) A-I      intronic chr20:6018364(+) A-I      3'UTR chr20:6018518(+) A-I      3'UTR chr20:6018371(+) A-I      3'UTR chr20:6018490(+) A-I      3'UTR chr20:6018487(+) A-I      3'UTR chr20:6018428(+) A-I      3'UTR chr20:6018368(+) A-I      3'UTR chr20:5998758(+) A-I      intronic chr20:5993933(+) A-I      intronic chr20:5992335(+) A-I      intronic chr20:5989849(+) A-I      intronic chr20:5989822(+) A-I      intronic chr20:5989816(+) A-I      intronic chr20:6014389(+) A-I      intronic chr20:6010041(+) A-I      intronic chr20:5998731(+) A-I      intronic chr20:5989813(+) A-I      intronic chr20:5998702(+) A-I      intronic chr20:5998688(+) A-I      intronic chr20:5998631(+) A-I      intronic chr20:5997773(+) A-I      intronic chr20:6011119(+) A-I      intronic chr20:5997754(+) A-I      intronic chr20:5993962(+) A-I      intronic chr20:5997707(+) A-I      intronic chr20:6011335(+) A-I      intronic chr20:6011173(+) A-I      intronic chr20:6000437(+) A-I      intronic chr20:6011114(+) A-I      intronic chr20:6011105(+) A-I      intronic chr20:6011097(+) A-I      intronic chr20:6010163(+) A-I      intronic chr20:5998807(+) A-I      intronic chr20:6008241(+) A-I      intronic chr20:6011140(+) A-I      intronic chr20:6003223(+) A-I      intronic chr20:6010134(+) A-I      intronic chr20:5998747(+) A-I      intronic chr20:5998700(+) A-I      intronic chr20:5998617(+) A-I      intronic chr20:6011299(+) A-I      intronic chr20:5997816(+) A-I      intronic chr20:5998804(+) A-I      intronic chr20:6004663(+) A-I      intronic chr20:6001761(+) A-I      intronic chr20:6010137(+) A-I      intronic chr20:5998678(+) A-I      intronic chr20:6019860(+) A-I      3'UTR chr20:5998663(+) A-I      intronic chr20:5993934(+) A-I      intronic chr20:5993958(+) A-I      intronic chr20:6010135(+) A-I      intronic chr20:6011253(+) A-I      intronic chr20:6011207(+) A-I      intronic chr20:6011367(+) A-I      intronic chr20:5998701(+) A-I      intronic chr20:6011183(+) A-I      intronic chr20:6000441(+) A-I      intronic chr20:5998704(+) A-I      intronic chr20:5993945(+) A-I      intronic chr20:5998783(+) A-I      intronic chr20:6010179(+) A-I      intronic chr20:6010279(+) A-I      intronic chr20:5998812(+) A-I      intronic chr20:6003111(+) A-I      intronic chr20:6010067(+) A-I      intronic chr20:6000507(+) A-I      intronic chr20:6003227(+) A-I      intronic chr20:5991481(+) A-I      intronic chr20:6011317(+) A-I      intronic chr20:6011136(+) A-I      intronic chr20:6010266(+) A-I      intronic chr20:6011298(+) A-I      intronic chr20:5998715(+) A-I      intronic chr20:5998608(+) A-I      intronic chr20:5991556(+) A-I      intronic chr20:5998665(+) A-I      intronic chr20:6000490(+) A-I      intronic chr20:5991569(+) A-I      intronic chr20:6010190(+) A-I      intronic chr20:6001852(+) A-I      intronic chr20:6001910(+) A-I      intronic chr20:6010072(+) A-I      intronic chr20:5998706(+) A-I      intronic chr20:6011204(+) A-I      intronic chr20:6011212(+) A-I      intronic chr20:5997763(+) A-I      intronic chr20:6000519(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CRLS1	chr20:6006381(+) A-I intron -    21960545 chr20:5998662(+) A-G intron -    22484847 chr20:5998741(+) A-G intron -    22484847 chr20:5998742(+) A-G intron -    22484847 chr20:6010179(+) A-G intron -    22484847 chr20:6010266(+) A-G intron -    22484847 chr20:6011212(+) A-G intron -    22484847 chr20:6011299(+) A-G intron -    22484847 chr20:6011353(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CRLS1	chr20:5986868-5986869(+) m6A 5'UTR       24981863 chr20:5987091-5987092(+) m6A CDS       - chr20:6017780-6017781(+) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085 chr20:6017799-6017800(+) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085 chr20:6017853-6017854(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr20:6017911-6017912(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr20:6018832-6018833(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CRLS1	Cytosol HCC cell line (HepG2)|K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US25-2-3p	Irinotecan       60838

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-3p
Interactor2: CRLS1

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg