Basic Information:

  VIRBase ID:  

VHID00234449

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:  MIMAT0001583          CCDC174:  NR_135523     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-3p	CCDC174
miRBase Accession/Entrez ID	MIMAT0001583	51244
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	C3orf19//ctr1//HSPC212//IHPM//IHPMR

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CCDC174	chr3:14704704(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CCDC174	chr3:14693256-14693257(+) m6A 5'UTR       - chr3:14693321-14693322(+) m6A 5'UTR//exon       25456834//24981863 chr3:14693327-14693328(+) m6A 5'UTR//exon       25456834//24981863 chr3:14693347-14693348(+) m6A 5'UTR//CDS//exon       24981863 chr3:14695979-14695980(+) m6A 5'UTR//CDS//exon       27773535 chr3:14695988-14695989(+) m6A 5'UTR//CDS//exon       27773535 chr3:14696018-14696019(+) m6A 5'UTR//CDS//exon       27773535 chr3:14696025-14696026(+) m6A 5'UTR//CDS//exon       27773535 chr3:14697037-14697038(+) m6A 5'UTR//CDS//exon       27773535 chr3:14697055-14697056(+) m6A 5'UTR//CDS//exon       27773535 chr3:14697097-14697098(+) m6A 5'UTR//CDS//exon       24981863//27773535 chr3:14697101-14697102(+) Am 5'UTR//CDS//exon       - chr3:14697112-14697113(+) m6A 5'UTR//CDS//exon       24981863//27773535 chr3:14697119-14697120(+) m6A 5'UTR//CDS//exon       24981863//27773535 chr3:14697126-14697127(+) m6A 5'UTR//CDS//exon       24981863//27773535 chr3:14700427-14700428(+) m6A CDS//exon       27773535 chr3:14703087-14703088(+) m6A CDS//exon       27773535 chr3:14703165-14703166(+) m6A CDS//exon       27773535 chr3:14703198-14703199(+) m6A CDS//exon       27773535 chr3:14708365-14708366(+) m6A CDS//exon       27773535 chr3:14708439-14708440(+) m6A CDS//exon       27773535 chr3:14708501-14708502(+) m6A exon//intron       27773535 chr3:14708512-14708513(+) m6A exon//intron       27773535 chr3:14708972-14708973(+) m6A CDS//intron       24981863//27773535//22608085 chr3:14708987-14708988(+) m6A CDS//intron       24981863//27773535//22608085 chr3:14709001-14709002(+) m6A CDS//intron       24981863//27773535//22608085 chr3:14709021-14709022(+) m6A CDS//intron       24981863//27773535//22608085 chr3:14709555-14709556(+) m6A CDS//exon//intron       24981863//27773535//22608085 chr3:14709570-14709571(+) m6A CDS//exon//intron       24981863//27773535//22608085 chr3:14709583-14709584(+) m6A CDS//exon//intron       24981863//27773535//22608085 chr3:14709620-14709621(+) m6A CDS//exon//intron       24981863//27773535//22608085 chr3:14709629-14709630(+) m6A CDS//exon//intron       24981863//27773535//22608085 chr3:14709669-14709670(+) m6A CDS//exon//intron       24209618//24981863//27773535//22608085 chr3:14711545-14711546(+) m6A CDS//exon       24209618//27773535//22608085 chr3:14711581-14711582(+) m6A CDS//exon       24284625//24209618//27773535//22608085 chr3:14712503-14712504(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22608085 chr3:14712535-14712536(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr3:14712586-14712587(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr3:14712598-14712599(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr3:14712659-14712660(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr3:14712688-14712689(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr3:14712776-14712777(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr3:14712819-14712820(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr3:14712860-14712861(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr3:14712904-14712905(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr3:14712968-14712969(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CCDC174	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US25-2-3p	Irinotecan       60838

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-3p
Interactor2: CCDC174

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg