Basic Information:

  VIRBase ID:  

VHID00233803

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:  MIMAT0001583          NET1:  NR_073040     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-3p	NET1
miRBase Accession/Entrez ID	MIMAT0001583	10276
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ARHGEF8//NET1A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NET1	chr10:5464048(+) A-I      intronic chr10:5478354(+) A-I      intronic chr10:5478329(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NET1	chr10:5488746-5488747(+) m6A CDS//exon//intron       24981863 chr10:5488773-5488774(+) m6A CDS//exon//intron       24981863 chr10:5497016-5497017(+) m6A CDS//exon       27773535 chr10:5497077-5497078(+) m6A CDS//exon       - chr10:5498051-5498052(+) m6A CDS//exon       - chr10:5498074-5498075(+) m6A CDS//exon       - chr10:5498739-5498740(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr10:5498758-5498759(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr10:5498859-5498860(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr10:5498876-5498877(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr10:5498885-5498886(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr10:5498913-5498914(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr10:5498945-5498946(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr10:5498988-5498989(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr10:5499806-5499807(+) m6A 3'UTR       27773535 chr10:5499834-5499835(+) m6A 3'UTR       27773535 chr10:5499848-5499849(+) m6A 3'UTR       27773535 chr10:5499983-5499984(+) m6A 3'UTR       27773535 chr10:5500065-5500066(+) m6A 3'UTR       27773535 chr10:5500115-5500116(+) m6A 3'UTR       27773535 chr10:5500186-5500187(+) m6A 3'UTR       27773535 chr10:5500348-5500349(+) m6A 3'UTR       24981863//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	NET1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US25-2-3p	Irinotecan       60838

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-3p
Interactor2: NET1

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg