Basic Information:

  VIRBase ID:  

VHID00232845

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:  MIMAT0001583          MTAP:  NM_002451     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-3p	MTAP
miRBase Accession/Entrez ID	MIMAT0001583	4507
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BDMF//c86fus//DMSFH//DMSMFH//HEL-249//LGMBF//MSAP

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MTAP	chr9:21810160(+) A-I      intronic chr9:21858373(+) A-I      intronic chr9:21808772(+) A-I      intronic chr9:21810302(+) A-I      intronic chr9:21817637(+) A-I      intronic chr9:21808799(+) A-I      intronic chr9:21828426(+) A-I      intronic chr9:21828424(+) A-I      intronic chr9:21828418(+) A-I      intronic chr9:21828472(+) A-I      intronic chr9:21865393(+) A-I      3'UTR chr9:21865388(+) A-I      3'UTR chr9:21865373(+) A-I      3'UTR chr9:21865386(+) A-I      3'UTR chr9:21865420(+) A-I      3'UTR chr9:21865153(+) A-I      3'UTR chr9:21865407(+) A-I      3'UTR chr9:21865368(+) A-I      3'UTR chr9:21865372(+) A-I      3'UTR chr9:21865371(+) A-I      3'UTR chr9:21865401(+) A-I      3'UTR chr9:21860907(+) A-I      intronic chr9:21863352(+) A-I      3'UTR chr9:21863456(+) A-I      3'UTR chr9:21840078(+) A-I      intronic chr9:21825596(+) A-I      intronic chr9:21840073(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MTAP	chr9:21808836(+) A-G intron -    22484847 chr9:21808899(+) A-G intron -    22484847 chr9:21844841(+) T-C intron -    22484847 chr9:21852508(+) C-A intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MTAP	chr9:21802745-21802746(+) m6A 5'UTR//exon       25456834//24981863 chr9:21815449-21815450(+) m6A CDS//exon       24981863 chr9:21855036-21855037(+) Am intron       - chr9:21862006-21862007(+) m6A 3'UTR//CDS//exon//intron       24284625//27773535//22608085 chr9:21862042-21862043(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22608085 chr9:21862101-21862102(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr9:21862150-21862151(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr9:21862155-21862156(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr9:21862173-21862174(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr9:21862190-21862191(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr9:21862229-21862230(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr9:21862270-21862271(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22608085 chr9:21862370-21862371(+) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085 chr9:21862448-21862449(+) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085 chr9:21862480-21862481(+) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr9:21862508-21862509(+) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr9:21862588-21862589(+) m6A 3'UTR//intron       24981863//22608085 chr9:21865356-21865357(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr9:21865372-21865373(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr9:21865432-21865433(+) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr9:21865476-21865477(+) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr9:21865533-21865534(+) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr9:21865555-21865556(+) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr9:21865606-21865607(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr9:21865622-21865623(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr9:21865670-21865671(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr9:21865691-21865692(+) m1A 3'UTR//intron       26863196 chr9:21865730-21865731(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr9:21865771-21865772(+) m6A 3'UTR//intron       24284625//25456834//22608085 chr9:21931080-21931081(+) m6A CDS//exon       24284625 chr9:21931088-21931089(+) m6A CDS//exon       24284625 chr9:21931104-21931105(+) m6A CDS//exon       24284625 chr9:21931142-21931143(+) m6A CDS//exon       24284625//25456834 chr9:21931210-21931211(+) m6A 3'UTR//exon       24284625//25456834 chr9:21931219-21931220(+) m6A 3'UTR//exon       24284625//25456834 chr9:21931263-21931264(+) m6A 3'UTR//exon       24284625//22608085 chr9:21931342-21931343(+) m6A 3'UTR//exon       24284625//22608085 chr9:21931362-21931363(+) m6A 3'UTR//exon       22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MTAP	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US25-2-3p	Irinotecan       60838

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-3p
Interactor2: MTAP

Evidence Support:

Prediction-Evidence	cRep//miRanda//Targetscan
Support Database	RepTar//VmiReg