Detail Information

Basic Information:


  VIRBase ID:  

VHID00232172

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-3p:           C2orf27A:      

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Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-2-3p C2orf27A
miRBase
Accession/Entrez ID		 MIMAT0001583 29798
Organism Human betaherpesvirus 5 (HHV-5) Homo sapiens
Category miRNA lncRNA
Alias - C2orf27//C2orf27B

RNA Editing:


Resource Symbol Editing Position
Lncediting C2orf27A
    chr2: 132516069
Resource Symbol Editing Position Change Genetic Region
RADAR C2orf27A
chr2:132516069(+) A-I      ncRNA
chr2:132519123(+) A-I      intronic
chr2:132522849(+) A-I      intronic
chr2:132516819(+) A-I      intronic
chr2:132517332(+) A-I      intronic
chr2:132517372(+) A-I      intronic
chr2:132519082(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED C2orf27A
chr2:132481382(+) A-I intron -    22327324
chr2:132481405(+) A-I intron -    22327324
chr2:132481410(+) A-I intron -    22327324
chr2:132522806(+) A-I intron -    22327324
chr2:132523436(+) A-T intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase C2orf27A
chr2:132480009-132480010(+) m6A exon       22608085
chr2:132480020-132480021(+) m6A exon       22608085
chr2:132480151-132480152(+) m6A exon       22608085
chr2:132480168-132480169(+) m6A exon       22608085
chr2:132480177-132480178(+) m6A exon       22608085
chr2:132515987-132515988(+) m6A exon//intron       -
chr2:132516025-132516026(+) m6A exon//intron       -
chr2:132516036-132516037(+) m6A exon//intron       -
chr2:132516061-132516062(+) m6A exon//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate C2orf27A
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug hcmv-miR-US25-2-3p
Irinotecan       60838
C2orf27A
9H-Purine, 6-(ethylthio)-9-beta-D-ribofuranosyl-(8CI)(9CI)       95846
6-Benzylthioinosine       95263
Pentamidine isethionate       8813
Benzethonium chloride       8478
5-Methyl-1,10-phenanthroline       72791
7-Hydroxystaurosporine       72271
Hydrastinine Hydrochloride       71833
2-Amino-6-methoxypurine       65275
Nilotinib       644241
4-(N-Hydroxyacetamido)stilbene       6433723
3-(2-Phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenol;hydrochloride       57399804
Methyl N-[6-[3-[[2-fluoro-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1H-benzimidazol-2-yl]carbamate;hydrochloride       57399798
Ethyl red       54832
Phyllanthastatin 1       5477587
Mito-tempol       54613387
Curromycin A.B mixture       54608021
2-Methylolivacinium acetate       5458752
Rubremetinium chloride       5351504
Purapuridine       5250
Alsterpaullone       5005498
Cardiovite       4951
Pentamidine       4735
2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one       4713
4-[1-(4-Aminomethyl-phenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-furazan-3-ylamine       44397453
Staurosporine       44259
Cyclamin       441916
Vemurafenib       42611257
1,6-Bis[4-(4-aminophenoxy)phenyl]diamantane       397904
1-(2-(Hydroxymethyl)-1,3-dioxolan-4-yl)cytosine       381525
2,3,6-Tribromo-7-chloro-3,7-dimethyloct-1-ene       377930
1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)-       362170
2,3-Dimethylbenzo[g]quinoxaline-5,10-dione       353644
4,6-Diamino-7-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile       300567
2-Benzoyloxymethyl-1,4-naphthoquinone       24206039
Tetrabutylammonium tris(pentafluoroethyl)trifluorophosphate       21977446
7-(alpha-Anilino-P-nitrobenzyl)-8-quinolinol       219565
Sorafenib       216239
Kinetin riboside       20345
Adiantifoline       167937
Homidium bromide       14710
N-[5-[5-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-pyridin-4-ylfuran-3-yl]-2,3-dihydroinden-1-ylidene]hydroxylamine;hydrochloride       136207967
4-[(5z)-5-(1-Nitroso-2,3-Dihydro-5h-Inden-5-Ylidene)-2-(Piperidin-4-Yl)-3,5-Dihydro-4h-Imidazol-4-Ylidene]-1,4-Dihydropyridine       136026031
Astrazon Orange R       135747272
N,N-Dimethyl-2-[4-[4-(1-nitroso-2,3-dihydroinden-5-ylidene)-5-(1H-pyridin-4-ylidene)-1H-imidazol-2-yl]phenoxy]ethanamine       135564599
Berberine chloride       12456
1-Methyl-5-[[2-[5-(trifluoromethyl)-1h-imidazol-2-yl]-4-pyridinyl]oxy]-n-[4-(trifluoromethyl)phenyl]-1h-benzimidazol-2-amine       11656518
Bafetinib       11387605
1-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazole       11162021
[(4-Methylphenyl)methyl](triphenyl)arsanium bromide       10672721
Dequalinium chloride       10649
Selumetinib       10127622
1,4-benzenediamine (9ci), n-butyl-n'-phenyl-       -
;2-(3-((2-methoxybenzyl)amino)propyl)-7-(3-((4-((3-(meth...       -
;4-fluoro-N-(3-(4-(6-(4-hydroxyphenyl)imidazo[2,1-b]thia...       -
5,6-ethylenediquino[3,2-b       -
Asparaginase       -
benzo[b]naphtho[2,3-d]furan-6,11-dione, 4-chloro-3-hydroxy       -
;(E)-3-(3-((1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)met...       -
gamitrinib-g4       -
gramicidin       -
g-tpp       -
naphtho[2,1-b]quinolizinium, 5-chloro-7-methyl- perchlorate       -
propanedinitrile, [(3,5-dibromo-2-ethoxyphenyl)methylene]-       -
protein toxin c 10 - mw approx. 6700       -
riboprine(usan)       -
Tyrothricin       -
;(Z)-5-Chloro-2-(1-methyl-5-nitroimidazole-2-ylmethylene...       -

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-2-3p
Interactor2: C2orf27A

Evidence Support:


Prediction-Evidence PITA//RNAHybrid
Support Database VmiReg

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