Detail Information

Basic Information:


  VIRBase ID:  

VHID00231549

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-5p:           WDR35:      

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Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-2-5p WDR35
miRBase
Accession/Entrez ID		 MIMAT0001582 57539
Organism Human betaherpesvirus 5 (HHV-5) Homo sapiens
Category miRNA mRNA
Alias - CED2//FAP118//IFT121//IFTA1//SRTD7

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR WDR35
chr2:20128763(-) A-I      intronic
chr2:20118936(-) A-I      intronic
chr2:20128722(-) A-I      intronic
chr2:20128682(-) A-I      intronic
chr2:20118937(-) A-I      intronic
chr2:20119090(-) A-I      intronic
chr2:20118960(-) A-I      intronic
chr2:20118957(-) A-I      intronic
chr2:20148613(-) A-I      intronic
chr2:20148628(-) A-I      intronic
chr2:20163486(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED WDR35
chr2:20113354(-) A-I exon CDS    19478186
chr2:20163485(-) A-G intron -    22484847
chr2:20163486(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase WDR35
chr2:20110038-20110039(-) m6A 3'UTR       27773535
chr2:20110113-20110114(-) m6A 3'UTR       27773535
chr2:20113812-20113813(-) m6A 3'UTR//CDS//intron       22608085
chr2:20113823-20113824(-) m6A 3'UTR//CDS//intron       22608085
chr2:20113847-20113848(-) m6A 3'UTR//CDS//intron       22608085
chr2:20113872-20113873(-) m6A 3'UTR//CDS//intron       22608085
chr2:20113886-20113887(-) m6A 3'UTR//CDS//intron       22608085
chr2:20113892-20113893(-) m6A 3'UTR//CDS//intron       22608085
chr2:20113906-20113907(-) m6A 3'UTR//CDS//intron       22608085
chr2:20113922-20113923(-) m6A 3'UTR//CDS//intron       24981863//22608085
chr2:20113945-20113946(-) m6A 3'UTR//CDS//intron       24284625//24981863//22608085
chr2:20114013-20114014(-) m6A 3'UTR//CDS//intron       24284625
chr2:20114022-20114023(-) m6A 3'UTR//CDS//intron       24284625
chr2:20130159-20130160(-) m6A 3'UTR//CDS       27773535
chr2:20130173-20130174(-) m6A 3'UTR//CDS       27773535
chr2:20131077-20131078(-) m6A 3'UTR//CDS       27773535
chr2:20131137-20131138(-) m6A 3'UTR//CDS       27773535
chr2:20132055-20132056(-) m6A CDS//intron       27773535
chr2:20132094-20132095(-) m6A CDS//intron       27773535
chr2:20132111-20132112(-) m6A CDS//intron       27773535
chr2:20136003-20136004(-) m6A 3'UTR//CDS       27773535
chr2:20136026-20136027(-) m6A 3'UTR//CDS       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hcmv-miR-US25-2-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
WDR35
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Membrane K562 cells     -
Nucleolus K562 cells     -
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-2-5p
Interactor2: WDR35

Evidence Support:


Prediction-Evidence cRep//miRanda//PITA//Targetscan
Support Database RepTar//VmiReg

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