Basic Information:

  VIRBase ID:  

VHID00231526

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-5p:  MIMAT0001582          TRIM54:  NM_187841     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-5p	TRIM54
miRBase Accession/Entrez ID	MIMAT0001582	57159
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	MURF//MURF-3//muRF3//RNF30

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TRIM54	chr2:27522399(+) A-I      NonSyn:Lys->Arg chr2:27585630(+) A-I      intronic chr2:27522479(+) A-I      NonSyn:Ser->Gly chr2:27522458(+) A-I      NonSyn:Ser->Gly chr2:27522440(+) A-I      NonSyn:Thr->Ala chr2:27552898(+) A-I      intronic chr2:27522513(+) A-I      NonSyn:Lys->Arg chr2:27522512(+) A-I      NonSyn:Lys->Glu chr2:27552914(+) A-I      intronic chr2:27552915(+) A-I      intronic chr2:27552922(+) A-I      intronic chr2:27552925(+) A-I      intronic chr2:27585634(+) A-I      intronic chr2:27552933(+) A-I      intronic chr2:27552938(+) A-I      intronic chr2:27583402(+) A-I      intronic chr2:27512643(+) A-I      intronic chr2:27512652(+) A-I      intronic chr2:27512656(+) A-I      intronic chr2:27512675(+) A-I      intronic chr2:27519788(+) A-I      intronic chr2:27519801(+) A-I      intronic chr2:27519807(+) A-I      intronic chr2:27519810(+) A-I      intronic chr2:27522713(+) A-I      intronic chr2:27519827(+) A-I      intronic chr2:27519848(+) A-I      intronic chr2:27519849(+) A-I      intronic chr2:27520745(+) A-I      intronic chr2:27520753(+) A-I      intronic chr2:27583405(+) A-I      intronic chr2:27583406(+) A-I      intronic chr2:27520777(+) A-I      intronic chr2:27520774(+) A-I      intronic chr2:27522496(+) A-I      Syn:Leu->Leu chr2:27583419(+) A-I      intronic chr2:27585013(+) A-I      intronic chr2:27585616(+) A-I      intronic chr2:27580261(+) A-I      intronic chr2:27580282(+) A-I      intronic chr2:27580456(+) A-I      intronic chr2:27580595(+) A-I      intronic chr2:27584561(+) A-I      intronic chr2:27525004(+) A-I      intronic chr2:27585595(+) A-I      intronic chr2:27585578(+) A-I      intronic chr2:27585480(+) A-I      intronic chr2:27585123(+) A-I      intronic chr2:27585063(+) A-I      intronic chr2:27585059(+) A-I      intronic chr2:27585054(+) A-I      intronic chr2:27585053(+) A-I      intronic chr2:27585010(+) A-I      intronic chr2:27584984(+) A-I      intronic chr2:27584959(+) A-I      intronic chr2:27584919(+) A-I      intronic chr2:27584480(+) A-I      intronic chr2:27584468(+) A-I      intronic chr2:27584382(+) A-I      intronic chr2:27584374(+) A-I      intronic chr2:27584080(+) A-I      intronic chr2:27583993(+) A-I      intronic chr2:27583992(+) A-I      intronic chr2:27583984(+) A-I      intronic chr2:27583333(+) A-I      intronic chr2:27580616(+) A-I      intronic chr2:27524191(+) A-I      intronic chr2:27580615(+) A-I      intronic chr2:27506916(+) A-I      intronic chr2:27506981(+) A-I      intronic chr2:27516803(+) A-I      intronic chr2:27517066(+) A-I      intronic chr2:27585043(+) A-I      intronic chr2:27517198(+) A-I      intronic chr2:27520769(+) A-I      intronic chr2:27523561(+) A-I      intronic chr2:27523589(+) A-I      intronic chr2:27523613(+) A-I      intronic chr2:27523765(+) A-I      intronic chr2:27523767(+) A-I      intronic chr2:27524085(+) A-I      intronic chr2:27524133(+) A-I      intronic chr2:27524174(+) A-I      intronic chr2:27510144(+) A-I      intronic chr2:27520734(+) A-I      intronic chr2:27510183(+) A-I      intronic chr2:27516770(+) A-I      intronic chr2:27516797(+) A-I      intronic chr2:27524189(+) A-I      intronic chr2:27524208(+) A-I      intronic chr2:27524217(+) A-I      intronic chr2:27524251(+) A-I      intronic chr2:27524268(+) A-I      intronic chr2:27524780(+) A-I      intronic chr2:27524812(+) A-I      intronic chr2:27525001(+) A-I      intronic chr2:27584009(+) A-I      intronic chr2:27585558(+) A-I      intronic chr2:27584047(+) A-I      intronic chr2:27584925(+) A-I      intronic chr2:27586458(+) A-I      intronic chr2:27580283(+) A-I      intronic chr2:27526920(+) A-I      intronic chr2:27584612(+) A-I      intronic chr2:27527026(+) A-I      intronic chr2:27584075(+) A-I      intronic chr2:27580606(+) A-I      intronic chr2:27583526(+) A-I      intronic chr2:27584611(+) A-I      intronic chr2:27584063(+) A-I      intronic chr2:27589479(+) A-I      intronic chr2:27585433(+) A-I      intronic chr2:27586939(+) A-I      intronic chr2:27580322(+) A-I      intronic chr2:27526959(+) A-I      intronic chr2:27526933(+) A-I      intronic chr2:27526886(+) A-I      intronic chr2:27584535(+) A-I      intronic chr2:27584126(+) A-I      intronic chr2:27527204(+) A-I      intronic chr2:27580556(+) A-I      intronic chr2:27584624(+) A-I      intronic chr2:27580260(+) A-I      intronic chr2:27585027(+) A-I      intronic chr2:27583969(+) A-I      intronic chr2:27583983(+) A-I      intronic chr2:27584027(+) A-I      intronic chr2:27583323(+) A-I      intronic chr2:27584161(+) A-I      intronic chr2:27586927(+) A-I      intronic chr2:27526826(+) A-I      intronic chr2:27586917(+) A-I      intronic chr2:27585442(+) A-I      intronic chr2:27526842(+) A-I      intronic chr2:27585099(+) A-I      intronic chr2:27527000(+) A-I      intronic chr2:27584532(+) A-I      intronic chr2:27583578(+) A-I      intronic chr2:27527184(+) A-I      intronic chr2:27584053(+) A-I      intronic chr2:27583960(+) A-I      intronic chr2:27527196(+) A-I      intronic chr2:27586755(+) A-I      intronic chr2:27531978(+) A-I      intronic chr2:27583892(+) A-I      intronic chr2:27583501(+) A-I      intronic chr2:27580247(+) A-I      intronic chr2:27585164(+) A-I      intronic chr2:27583908(+) A-I      intronic chr2:27584125(+) A-I      intronic chr2:27585643(+) A-I      intronic chr2:27580295(+) A-I      intronic chr2:27583487(+) A-I      intronic chr2:27583441(+) A-I      intronic chr2:27580312(+) A-I      intronic chr2:27580628(+) A-I      intronic chr2:27527203(+) A-I      intronic chr2:27527202(+) A-I      intronic chr2:27584973(+) A-I      intronic chr2:27526921(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TRIM54	chr2:27529960-27529961(+) m6A 3'UTR       25456834 chr2:27529967-27529968(+) m6A 3'UTR       25456834 chr2:27529994-27529995(+) m6A 3'UTR       25456834 chr2:27530029-27530030(+) m6A 3'UTR       25456834 chr2:27530084-27530085(+) m6A 3'UTR       25456834 chr2:27530110-27530111(+) m6A 3'UTR       25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-US25-2-5p	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	TRIM54	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-5p
Interactor2: TRIM54

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg