Basic Information:

  VIRBase ID:  

VHID00231429

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-5p:  MIMAT0001582          GDAP2:  NM_017686     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-5p	GDAP2
miRBase Accession/Entrez ID	MIMAT0001582	54834
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	MACROD3//SCAR27

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	GDAP2	chr1:118410066(-) A-I      3'UTR chr1:118409393(-) A-I      3'UTR chr1:118410093(-) A-I      3'UTR chr1:118410094(-) A-I      3'UTR chr1:118410106(-) A-I      3'UTR chr1:118454482(-) A-I      intronic chr1:118442782(-) A-I      intronic chr1:118409363(-) A-I      3'UTR

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	GDAP2	chr1:118411860-118411861(-) m6A 3'UTR       27773535 chr1:118411885-118411886(-) m6A 3'UTR       27773535 chr1:118412587-118412588(-) m6A 3'UTR       22608085 chr1:118412601-118412602(-) m6A 3'UTR       22608085 chr1:118412628-118412629(-) m6A 3'UTR       27773535//22608085 chr1:118412635-118412636(-) m6A 3'UTR       27773535//22608085 chr1:118412655-118412656(-) m6A 3'UTR       27773535//22608085 chr1:118412792-118412793(-) m6A 3'UTR       24981863//27773535 chr1:118412862-118412863(-) m6A 3'UTR//exon       24981863//27773535//22608085 chr1:118412871-118412872(-) m6A 3'UTR//exon       24981863//27773535//22608085 chr1:118412894-118412895(-) m6A 3'UTR//exon       24981863//27773535//22608085 chr1:118413002-118413003(-) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr1:118419944-118419945(-) m6A 3'UTR//intron       27773535 chr1:118472189-118472190(-) m6A 5'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-US25-2-5p	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	GDAP2	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-5p
Interactor2: GDAP2

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg