Basic Information:

  VIRBase ID:  

VHID00230971

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-2-5p:  MIMAT0001582          SLC5A6:  NR_028323     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-2-5p	SLC5A6
miRBase Accession/Entrez ID	MIMAT0001582	8884
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	NERIB//SMVT

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SLC5A6	chr2:27433540(-) A-I      intronic chr2:27433773(-) A-I      intronic chr2:27433780(-) A-I      intronic chr2:27433792(-) A-I      intronic chr2:27433423(-) A-I      intronic chr2:27433487(-) A-I      intronic chr2:27433490(-) A-I      intronic chr2:27433491(-) A-I      intronic chr2:27433463(-) A-I      intronic chr2:27433829(-) A-I      intronic chr2:27433450(-) A-I      intronic chr2:27433525(-) A-I      intronic chr2:27433485(-) A-I      intronic chr2:27433515(-) A-I      intronic chr2:27433557(-) A-I      intronic chr2:27433364(-) A-I      intronic chr2:27433313(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SLC5A6	chr2:27433515(-) A-G intron -    22484847 chr2:27433516(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SLC5A6	chr2:27422619-27422620(-) m6A 3'UTR//exon       24284625//24981863//26404942 chr2:27422654-27422655(-) m6A 3'UTR//exon       24284625//24981863//26404942 chr2:27422898-27422899(-) m6A 3'UTR//exon//intron       24284625//24209618//24981863//28052920//26404942//27773535//22608085 chr2:27422917-27422918(-) m6A 3'UTR//exon//intron       24284625//24209618//24981863//28052920//26404942//27773535//22608085 chr2:27422957-27422958(-) m6A 3'UTR//exon//intron       24284625//24209618//24981863//28052920//26404942//27773535//22608085 chr2:27423174-27423175(-) m6A 3'UTR//exon       24284625//25456834//24981863//26404942 chr2:27423206-27423207(-) m6A 3'UTR//exon       24284625//25456834//24981863//26404942//27371828 chr2:27423290-27423291(-) m6A 3'UTR//exon       24284625//25456834//24981863//27371828//27773536 chr2:27423314-27423315(-) m6A CDS//exon       24284625//25456834//24981863//27371828//27773536 chr2:27423382-27423383(-) m6A CDS//exon       24284625//27371828//27773536 chr2:27423391-27423392(-) m6A CDS//exon       24284625//27371828//27773536 chr2:27424300-27424301(-) Y CDS//exon       26075521 chr2:27430229-27430230(-) m6A CDS//exon       24284625 chr2:27430330-27430331(-) m6A CDS//exon       24284625 chr2:27430435-27430436(-) m6A CDS//exon       24284625//24981863//22608085 chr2:27430530-27430531(-) m6A 5'UTR//exon       24284625//24981863//27371828//22608085 chr2:27430616-27430617(-) m6A 5'UTR//exon       24284625//24981863//27371828//27773536 chr2:27430624-27430625(-) m6A 5'UTR//exon       24284625//24981863//27371828//27773536 chr2:27430647-27430648(-) m6A 5'UTR//exon       24284625//27371828//27773536 chr2:27431499-27431500(-) m6A 5'UTR//intron       24284625//27773536 chr2:27434342-27434343(-) m6A 5'UTR//exon       24209618//24981863 chr2:27434362-27434363(-) m6A 5'UTR//exon       24209618//24981863 chr2:27434594-27434595(-) m6A 5'UTR//intron       24209618//24981863 chr2:27434882-27434883(-) m6A 5'UTR//intron       24284625//25456834//24981863 chr2:27434911-27434912(-) m6A 5'UTR//exon//intron       24284625//25456834//24981863//22608085 chr2:27434967-27434968(-) m6A 5'UTR//exon//intron       24284625//25456834//24981863//22608085 chr2:27435348-27435349(-) m6A 5'UTR//intron       25456834//24981863//27371828 chr2:27435521-27435522(-) m6A 5'UTR//intron       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-US25-2-5p	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	SLC5A6	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-2-5p
Interactor2: SLC5A6

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg