Basic Information:

  VIRBase ID:  

VHID00230207

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-2-3p:  MIMAT0001580          ZNF621:  NM_198484     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-2-3p	ZNF621
miRBase Accession/Entrez ID	MIMAT0001580	285268
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ZNF621	chr3:40579784(+) A-I      Syn:Ser->Ser chr3:40579814(+) A-I      NonSyn:Stp->Trp chr3:40579803(+) A-I      NonSyn:Arg->Gly chr3:40579794(+) A-I      NonSyn:Arg->Gly chr3:40589971(+) A-I      intronic chr3:40589998(+) A-I      intronic chr3:40590036(+) A-I      intronic chr3:40590676(+) A-I      intronic chr3:40590727(+) A-I      intronic chr3:40591515(+) A-I      intronic chr3:40592169(+) A-I      intronic chr3:40592205(+) A-I      intronic chr3:40592346(+) A-I      intronic chr3:40592352(+) A-I      intronic chr3:40592600(+) A-I      intronic chr3:40592677(+) A-I      intronic chr3:40595032(+) A-I      intronic chr3:40595058(+) A-I      intronic chr3:40592176(+) A-I      intronic chr3:40573187(+) A-I      intronic chr3:40586656(+) A-I      intronic chr3:40592180(+) A-I      intronic chr3:40592193(+) A-I      intronic chr3:40582273(+) A-I      intronic chr3:40582334(+) A-I      intronic chr3:40582399(+) A-I      intronic chr3:40582416(+) A-I      intronic chr3:40582598(+) A-I      intronic chr3:40582603(+) A-I      intronic chr3:40582611(+) A-I      intronic chr3:40582717(+) A-I      intronic chr3:40582730(+) A-I      intronic chr3:40582733(+) A-I      intronic chr3:40583566(+) A-I      intronic chr3:40584452(+) A-I      intronic chr3:40584887(+) A-I      intronic chr3:40586582(+) A-I      intronic chr3:40586694(+) A-I      intronic chr3:40586699(+) A-I      intronic chr3:40589575(+) A-I      intronic chr3:40589578(+) A-I      intronic chr3:40589616(+) A-I      intronic chr3:40589649(+) A-I      intronic chr3:40589663(+) A-I      intronic chr3:40589674(+) A-I      intronic chr3:40589675(+) A-I      intronic chr3:40589952(+) A-I      intronic chr3:40589972(+) A-I      intronic chr3:40590079(+) A-I      intronic chr3:40590088(+) A-I      intronic chr3:40590102(+) A-I      intronic chr3:40591522(+) A-I      intronic chr3:40591557(+) A-I      intronic chr3:40591567(+) A-I      intronic chr3:40591593(+) A-I      intronic chr3:40592155(+) A-I      intronic chr3:40592241(+) A-I      intronic chr3:40592242(+) A-I      intronic chr3:40592255(+) A-I      intronic chr3:40592305(+) A-I      intronic chr3:40592313(+) A-I      intronic chr3:40592327(+) A-I      intronic chr3:40592345(+) A-I      intronic chr3:40592604(+) A-I      intronic chr3:40592609(+) A-I      intronic chr3:40592610(+) A-I      intronic chr3:40592651(+) A-I      intronic chr3:40592654(+) A-I      intronic chr3:40592714(+) A-I      intronic chr3:40592719(+) A-I      intronic chr3:40592759(+) A-I      intronic chr3:40592783(+) A-I      intronic chr3:40592784(+) A-I      intronic chr3:40593741(+) A-I      intronic chr3:40593774(+) A-I      intronic chr3:40593850(+) A-I      intronic chr3:40593885(+) A-I      intronic chr3:40593886(+) A-I      intronic chr3:40593887(+) A-I      intronic chr3:40595151(+) A-I      intronic chr3:40595158(+) A-I      intronic chr3:40595175(+) A-I      intronic chr3:40595196(+) A-I      intronic chr3:40595243(+) A-I      intronic chr3:40595984(+) A-I      intronic chr3:40596212(+) A-I      intronic chr3:40596226(+) A-I      intronic chr3:40596229(+) A-I      intronic chr3:40578897(+) A-I      3'UTR chr3:40579039(+) A-I      3'UTR chr3:40577727(+) A-I      3'UTR chr3:40579924(+) A-I      3'UTR chr3:40574866(+) A-I      3'UTR chr3:40579910(+) A-I      3'UTR chr3:40579054(+) A-I      3'UTR chr3:40578943(+) A-I      3'UTR chr3:40579754(+) A-I      3'UTR chr3:40578979(+) A-I      3'UTR chr3:40580989(+) A-I      3'UTR chr3:40580977(+) A-I      3'UTR chr3:40577849(+) A-I      3'UTR chr3:40580936(+) A-I      3'UTR chr3:40580935(+) A-I      3'UTR chr3:40579770(+) A-I      3'UTR chr3:40579833(+) A-I      3'UTR chr3:40578859(+) A-I      3'UTR chr3:40579845(+) A-I      3'UTR chr3:40579854(+) A-I      3'UTR chr3:40579963(+) A-I      3'UTR chr3:40580974(+) A-I      3'UTR chr3:40579740(+) A-I      3'UTR chr3:40579857(+) A-I      3'UTR chr3:40577814(+) A-I      3'UTR chr3:40577761(+) A-I      3'UTR chr3:40578860(+) A-I      3'UTR chr3:40578907(+) A-I      3'UTR chr3:40574815(+) A-I      3'UTR chr3:40579028(+) A-I      3'UTR chr3:40579935(+) A-I      3'UTR chr3:40592319(+) A-I      intronic chr3:40589704(+) A-I      intronic chr3:40584775(+) A-I      intronic chr3:40595019(+) A-I      intronic chr3:40591528(+) A-I      intronic chr3:40591703(+) A-I      intronic chr3:40590051(+) A-I      intronic chr3:40583708(+) A-I      intronic chr3:40590678(+) A-I      intronic chr3:40592671(+) A-I      intronic chr3:40589660(+) A-I      intronic chr3:40586721(+) A-I      intronic chr3:40582703(+) A-I      intronic chr3:40582635(+) A-I      intronic chr3:40582765(+) A-I      intronic chr3:40584181(+) A-I      intronic chr3:40584834(+) A-I      intronic chr3:40592736(+) A-I      intronic chr3:40589740(+) A-I      intronic chr3:40589993(+) A-I      intronic chr3:40592684(+) A-I      intronic chr3:40589996(+) A-I      intronic chr3:40584586(+) A-I      intronic chr3:40590050(+) A-I      intronic chr3:40591676(+) A-I      intronic chr3:40583820(+) A-I      intronic chr3:40584011(+) A-I      intronic chr3:40590753(+) A-I      intronic chr3:40592202(+) A-I      intronic chr3:40581332(+) A-I      intronic chr3:40584919(+) A-I      intronic chr3:40583649(+) A-I      intronic chr3:40577737(+) A-I      3'UTR chr3:40579003(+) A-I      3'UTR chr3:40579844(+) A-I      3'UTR chr3:40578911(+) A-I      3'UTR chr3:40578831(+) A-I      3'UTR chr3:40579916(+) A-I      3'UTR chr3:40577746(+) A-I      3'UTR chr3:40574894(+) A-I      3'UTR chr3:40579742(+) A-I      3'UTR chr3:40577738(+) A-I      3'UTR chr3:40577781(+) A-I      3'UTR chr3:40577837(+) A-I      3'UTR chr3:40579757(+) A-I      3'UTR chr3:40578947(+) A-I      3'UTR chr3:40577684(+) A-I      3'UTR chr3:40574712(+) A-I      3'UTR chr3:40577604(+) A-I      3'UTR chr3:40578861(+) A-I      3'UTR chr3:40579748(+) A-I      3'UTR chr3:40578934(+) A-I      3'UTR chr3:40579035(+) A-I      3'UTR chr3:40577685(+) A-I      3'UTR chr3:40577769(+) A-I      3'UTR chr3:40577665(+) A-I      3'UTR chr3:40578933(+) A-I      3'UTR chr3:40577851(+) A-I      3'UTR chr3:40574732(+) A-I      3'UTR chr3:40579851(+) A-I      3'UTR chr3:40579929(+) A-I      3'UTR chr3:40574867(+) A-I      3'UTR chr3:40578973(+) A-I      3'UTR chr3:40577810(+) A-I      3'UTR chr3:40579893(+) A-I      3'UTR chr3:40579944(+) A-I      3'UTR chr3:40578910(+) A-I      3'UTR chr3:40578867(+) A-I      3'UTR chr3:40578929(+) A-I      3'UTR chr3:40579828(+) A-I      3'UTR chr3:40577649(+) A-I      3'UTR chr3:40578939(+) A-I      3'UTR chr3:40578997(+) A-I      3'UTR chr3:40578935(+) A-I      3'UTR chr3:40580009(+) A-I      3'UTR chr3:40579775(+) A-I      3'UTR chr3:40577603(+) A-I      3'UTR chr3:40577714(+) A-I      3'UTR chr3:40579839(+) A-I      3'UTR chr3:40579014(+) A-I      3'UTR chr3:40579843(+) A-I      3'UTR chr3:40577836(+) A-I      3'UTR chr3:40579755(+) A-I      3'UTR chr3:40577755(+) A-I      3'UTR chr3:40578990(+) A-I      3'UTR chr3:40578883(+) A-I      3'UTR chr3:40578878(+) A-I      3'UTR chr3:40591650(+) A-I      intronic chr3:40595052(+) A-I      intronic chr3:40582297(+) A-I      intronic chr3:40583564(+) A-I      intronic chr3:40584529(+) A-I      intronic chr3:40615176(+) A-I      intronic chr3:40592672(+) A-I      intronic chr3:40592668(+) A-I      intronic chr3:40584050(+) A-I      intronic chr3:40592124(+) A-I      intronic chr3:40582477(+) A-I      intronic chr3:40582478(+) A-I      intronic chr3:40593700(+) A-I      intronic chr3:40583764(+) A-I      intronic chr3:40592683(+) A-I      intronic chr3:40595075(+) A-I      intronic chr3:40590757(+) A-I      intronic chr3:40589824(+) A-I      intronic chr3:40589554(+) A-I      intronic chr3:40591649(+) A-I      intronic chr3:40592623(+) A-I      intronic chr3:40592284(+) A-I      intronic chr3:40591611(+) A-I      intronic chr3:40586709(+) A-I      intronic chr3:40582240(+) A-I      intronic chr3:40592723(+) A-I      intronic chr3:40590740(+) A-I      intronic chr3:40583642(+) A-I      intronic chr3:40590721(+) A-I      intronic chr3:40591651(+) A-I      intronic chr3:40583612(+) A-I      intronic chr3:40596030(+) A-I      intronic chr3:40596095(+) A-I      intronic chr3:40581371(+) A-I      intronic chr3:40591664(+) A-I      intronic chr3:40589596(+) A-I      intronic chr3:40592131(+) A-I      intronic chr3:40584049(+) A-I      intronic chr3:40583777(+) A-I      intronic chr3:40595978(+) A-I      intronic chr3:40592258(+) A-I      intronic chr3:40584513(+) A-I      intronic chr3:40584789(+) A-I      intronic chr3:40592331(+) A-I      intronic chr3:40592687(+) A-I      intronic chr3:40589714(+) A-I      intronic chr3:40595111(+) A-I      intronic chr3:40593696(+) A-I      intronic chr3:40589749(+) A-I      intronic chr3:40582430(+) A-I      intronic chr3:40584083(+) A-I      intronic chr3:40596137(+) A-I      intronic chr3:40590703(+) A-I      intronic chr3:40583752(+) A-I      intronic chr3:40582418(+) A-I      intronic chr3:40567946(+) A-I      intronic chr3:40589570(+) A-I      intronic chr3:40584089(+) A-I      intronic chr3:40584503(+) A-I      intronic chr3:40596126(+) A-I      intronic chr3:40582744(+) A-I      intronic chr3:40589754(+) A-I      intronic chr3:40589920(+) A-I      intronic chr3:40592618(+) A-I      intronic chr3:40592215(+) A-I      intronic chr3:40591711(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ZNF621	chr3:40577603(+) A-I intron -    22327324 chr3:40577685(+) A-I intron -    22327324 chr3:40577738(+) A-I intron -    21960545   //22327324 chr3:40578831(+) A-I intron -    22327324 chr3:40578932(+) A-I intron -    22327324 chr3:40578933(+) A-I intron -    22327324 chr3:40578939(+) A-I intron -    21960545   //22327324 chr3:40578940(+) A-I intron -    21960545   //22327324 chr3:40578942(+) A-I intron -    21960545   //22327324 chr3:40578997(+) A-I intron -    21960545   //22327324 chr3:40577737(+) A-I intron -    21960545 chr3:40578815(+) A-I intron -    21960545 chr3:40578843(+) A-I intron -    21960545 chr3:40578973(+) A-I intron -    21960545 chr3:40577685(+) A-G intron -    21725310   //22484847 chr3:40573275(+) G-A intron -    22484847 chr3:40577603(+) A-G intron -    22484847 chr3:40577649(+) A-G intron -    22484847 chr3:40577684(+) A-G intron -    22484847 chr3:40577737(+) A-G intron -    22484847 chr3:40577738(+) A-G intron -    22484847 chr3:40577745(+) A-G intron -    22484847 chr3:40577746(+) A-G intron -    22484847 chr3:40577752(+) A-G intron -    22484847 chr3:40577755(+) A-G intron -    22484847 chr3:40577769(+) A-G intron -    22484847 chr3:40577781(+) A-G intron -    22484847 chr3:40577810(+) A-G intron -    22484847 chr3:40577835(+) A-G intron -    22484847 chr3:40578831(+) A-G intron -    22484847 chr3:40578843(+) A-G intron -    22484847 chr3:40578931(+) A-G intron -    22484847 chr3:40578932(+) A-G intron -    22484847 chr3:40578933(+) A-G intron -    22484847 chr3:40578934(+) A-G intron -    22484847 chr3:40578935(+) A-G intron -    22484847 chr3:40578939(+) A-G intron -    22484847 chr3:40578940(+) A-G intron -    22484847 chr3:40578941(+) A-G intron -    22484847 chr3:40578942(+) A-G intron -    22484847 chr3:40578997(+) A-G intron -    22484847 chr3:40579748(+) A-G intron -    22484847 chr3:40579749(+) A-G intron -    22484847 chr3:40579755(+) A-G intron -    22484847 chr3:40579842(+) A-G intron -    22484847 chr3:40579843(+) A-G intron -    22484847 chr3:40579851(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ZNF621	chr3:40571718-40571719(+) m6A 5'UTR//CDS//exon       24284625 chr3:40571777-40571778(+) m6A 5'UTR//CDS//exon       24284625//24981863//22608085 chr3:40573579-40573580(+) m6A 5'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr3:40573608-40573609(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr3:40573663-40573664(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr3:40573859-40573860(+) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr3:40573959-40573960(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr3:40574043-40574044(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr3:40574127-40574128(+) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr3:40576308-40576309(+) m6A 3'UTR//intron       24284625 chr3:40576392-40576393(+) m6A 3'UTR//intron       24284625 chr3:40576594-40576595(+) m6A 3'UTR//intron       24284625 chr3:40576645-40576646(+) m6A 3'UTR//intron       24284625//24209618 chr3:40576759-40576760(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr3:40576839-40576840(+) m6A 3'UTR//intron       24284625//24209618//24981863//22608085 chr3:40576955-40576956(+) m6A 3'UTR//intron       24284625//25456834//24981863//22608085 chr3:40576975-40576976(+) m6A 3'UTR//intron       24284625//25456834//24981863//22608085 chr3:40577004-40577005(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr3:40577026-40577027(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr3:40577031-40577032(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr3:40577390-40577391(+) m6A 3'UTR//intron       24981863//27773535//22608085 chr3:40577435-40577436(+) m6A 3'UTR//intron       24981863//27773535//22608085 chr3:40577464-40577465(+) m6A 3'UTR//intron       24981863//27773535//22608085 chr3:40577514-40577515(+) m6A 3'UTR//intron       24981863//27773535//22608085 chr3:40577521-40577522(+) m6A 3'UTR//intron       24981863//22608085 chr3:40577533-40577534(+) m6A 3'UTR//intron       24981863//22608085 chr3:40577546-40577547(+) m6A 3'UTR//intron       24981863//22608085 chr3:40577558-40577559(+) m6A 3'UTR//intron       24981863//22608085 chr3:40577567-40577568(+) m6A 3'UTR//intron       24981863//22608085 chr3:40577575-40577576(+) m6A 3'UTR//intron       24981863//22608085 chr3:40579144-40579145(+) m6A 3'UTR//intron       - chr3:40579171-40579172(+) m6A 3'UTR//intron       - chr3:40579804-40579805(+) m6A CDS//intron       - chr3:40580243-40580244(+) m6A 3'UTR//intron       - chr3:40580283-40580284(+) m6A 3'UTR//intron       - chr3:40580339-40580340(+) m6A 3'UTR//intron       - chr3:40580381-40580382(+) m6A 3'UTR//intron       - chr3:40580433-40580434(+) m6A 3'UTR//intron       - chr3:40580446-40580447(+) m6A 3'UTR//intron       - chr3:40580492-40580493(+) m6A 3'UTR//intron       - chr3:40580549-40580550(+) m6A 3'UTR//intron       - chr3:40580598-40580599(+) m6A 3'UTR//intron       - chr3:40580616-40580617(+) m6A 3'UTR//intron       - chr3:40580630-40580631(+) m6A 3'UTR//intron       - chr3:40580855-40580856(+) m6A 3'UTR//intron       - chr3:40580875-40580876(+) m6A 3'UTR//intron       - chr3:40580886-40580887(+) m6A 3'UTR//intron       - chr3:40615895-40615896(+) m6A exon       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ZNF621	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-2-3p
Interactor2: ZNF621

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg