Basic Information:

  VIRBase ID:  

VHID00229360

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-2-3p:  MIMAT0001580          XRN1:  NM_001282859     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-2-3p	XRN1
miRBase Accession/Entrez ID	MIMAT0001580	54464
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	SEP1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	XRN1	chr3:142051040(-) A-I      intronic chr3:142146058(-) A-I      intronic chr3:142032696(-) A-I      intronic chr3:142051041(-) A-I      intronic chr3:142051045(-) A-I      intronic chr3:142051058(-) A-I      intronic chr3:142116827(-) A-I      intronic chr3:142086046(-) A-I      intronic chr3:142107898(-) A-I      intronic chr3:142107900(-) A-I      intronic chr3:142107907(-) A-I      intronic chr3:142107936(-) A-I      intronic chr3:142107943(-) A-I      intronic chr3:142076397(-) A-I      intronic chr3:142076438(-) A-I      intronic chr3:142076704(-) A-I      intronic chr3:142076798(-) A-I      intronic chr3:142076804(-) A-I      intronic chr3:142116863(-) A-I      intronic chr3:142076833(-) A-I      intronic chr3:142080873(-) A-I      intronic chr3:142081896(-) A-I      intronic chr3:142080903(-) A-I      intronic chr3:142080916(-) A-I      intronic chr3:142080935(-) A-I      intronic chr3:142108473(-) A-I      intronic chr3:142108499(-) A-I      intronic chr3:142108506(-) A-I      intronic chr3:142080971(-) A-I      intronic chr3:142108526(-) A-I      intronic chr3:142108544(-) A-I      intronic chr3:142108556(-) A-I      intronic chr3:142108589(-) A-I      intronic chr3:142108653(-) A-I      intronic chr3:142110360(-) A-I      intronic chr3:142110559(-) A-I      intronic chr3:142112731(-) A-I      intronic chr3:142112846(-) A-I      intronic chr3:142035651(-) A-I      intronic chr3:142035664(-) A-I      intronic chr3:142041072(-) A-I      intronic chr3:142041278(-) A-I      intronic chr3:142080975(-) A-I      intronic chr3:142112896(-) A-I      intronic chr3:142033958(-) A-I      intronic chr3:142034380(-) A-I      intronic chr3:142041294(-) A-I      intronic chr3:142041602(-) A-I      intronic chr3:142041604(-) A-I      intronic chr3:142041653(-) A-I      intronic chr3:142041726(-) A-I      intronic chr3:142041733(-) A-I      intronic chr3:142034386(-) A-I      intronic chr3:142034462(-) A-I      intronic chr3:142042212(-) A-I      intronic chr3:142034624(-) A-I      intronic chr3:142148200(-) A-I      intronic chr3:142148170(-) A-I      intronic chr3:142148169(-) A-I      intronic chr3:142148160(-) A-I      intronic chr3:142147233(-) A-I      intronic chr3:142147154(-) A-I      intronic chr3:142145979(-) A-I      intronic chr3:142145926(-) A-I      intronic chr3:142143081(-) A-I      intronic chr3:142143074(-) A-I      intronic chr3:142143004(-) A-I      intronic chr3:142139402(-) A-I      intronic chr3:142139393(-) A-I      intronic chr3:142139391(-) A-I      intronic chr3:142139362(-) A-I      intronic chr3:142138646(-) A-I      intronic chr3:142138502(-) A-I      intronic chr3:142138488(-) A-I      intronic chr3:142135789(-) A-I      intronic chr3:142135711(-) A-I      intronic chr3:142135706(-) A-I      intronic chr3:142135644(-) A-I      intronic chr3:142135298(-) A-I      intronic chr3:142135163(-) A-I      intronic chr3:142135066(-) A-I      intronic chr3:142134834(-) A-I      intronic chr3:142133610(-) A-I      intronic chr3:142133566(-) A-I      intronic chr3:142133539(-) A-I      intronic chr3:142133516(-) A-I      intronic chr3:142117441(-) A-I      intronic chr3:142117381(-) A-I      intronic chr3:142117333(-) A-I      intronic chr3:142117332(-) A-I      intronic chr3:142117320(-) A-I      intronic chr3:142117306(-) A-I      intronic chr3:142117301(-) A-I      intronic chr3:142117298(-) A-I      intronic chr3:142116987(-) A-I      intronic chr3:142116947(-) A-I      intronic chr3:142116929(-) A-I      intronic chr3:142035219(-) A-I      intronic chr3:142050845(-) A-I      intronic chr3:142051096(-) A-I      intronic chr3:142062213(-) A-I      intronic chr3:142050851(-) A-I      intronic chr3:142107972(-) A-I      intronic chr3:142041921(-) A-I      intronic chr3:142116838(-) A-I      intronic chr3:142086066(-) A-I      intronic chr3:142033957(-) A-I      intronic chr3:142076660(-) A-I      intronic chr3:142135131(-) A-I      intronic chr3:142081184(-) A-I      intronic chr3:142120442(-) A-I      intronic chr3:142110562(-) A-I      intronic chr3:142032673(-) A-I      intronic chr3:142086567(-) A-I      intronic chr3:142112888(-) A-I      intronic chr3:142108565(-) A-I      intronic chr3:142147210(-) A-I      intronic chr3:142032755(-) A-I      intronic chr3:142135110(-) A-I      intronic chr3:142041207(-) A-I      intronic chr3:142041404(-) A-I      intronic chr3:142081820(-) A-I      intronic chr3:142134881(-) A-I      intronic chr3:142076686(-) A-I      intronic chr3:142081769(-) A-I      intronic chr3:142135100(-) A-I      intronic chr3:142076393(-) A-I      intronic chr3:142085964(-) A-I      intronic chr3:142121122(-) A-I      intronic chr3:142133453(-) A-I      intronic chr3:142116892(-) A-I      intronic chr3:142047669(-) A-I      intronic chr3:142041204(-) A-I      intronic chr3:142081767(-) A-I      intronic chr3:142076542(-) A-I      intronic chr3:142153484(-) A-I      intronic chr3:142079653(-) A-I      intronic chr3:142117408(-) A-I      intronic chr3:142151254(-) A-I      intronic chr3:142134841(-) A-I      intronic chr3:142030884(-) A-I      intronic chr3:142032744(-) A-I      intronic chr3:142151211(-) A-I      intronic chr3:142051027(-) A-I      intronic chr3:142033997(-) A-I      intronic chr3:142033955(-) A-I      intronic chr3:142135719(-) A-I      intronic chr3:142076793(-) A-I      intronic chr3:142041934(-) A-I      intronic chr3:142117019(-) A-I      intronic chr3:142120363(-) A-I      intronic chr3:142133632(-) A-I      intronic chr3:142100546(-) A-I      intronic chr3:142135084(-) A-I      intronic chr3:142116992(-) A-I      intronic chr3:142041154(-) A-I      intronic chr3:142034011(-) A-I      intronic chr3:142076758(-) A-I      intronic chr3:142051044(-) A-I      intronic chr3:142086564(-) A-I      intronic chr3:142133410(-) A-I      intronic chr3:142112964(-) A-I      intronic chr3:142028317(-) A-I      3'UTR chr3:142133532(-) A-I      intronic chr3:142034056(-) A-I      intronic chr3:142035650(-) A-I      intronic chr3:142116867(-) A-I      intronic chr3:142076661(-) A-I      intronic chr3:142033986(-) A-I      intronic chr3:142129408(-) A-I      intronic chr3:142081077(-) A-I      intronic chr3:142138527(-) A-I      intronic chr3:142065499(-) A-I      intronic chr3:142076756(-) A-I      intronic chr3:142135198(-) A-I      intronic chr3:142042296(-) A-I      intronic chr3:142033638(-) A-I      intronic chr3:142033879(-) A-I      intronic chr3:142135708(-) A-I      intronic chr3:142116866(-) A-I      intronic chr3:142035199(-) A-I      intronic chr3:142034447(-) A-I      intronic chr3:142138494(-) A-I      intronic chr3:142135623(-) A-I      intronic chr3:142081737(-) A-I      intronic chr3:142042640(-) A-I      intronic chr3:142041180(-) A-I      intronic chr3:142081685(-) A-I      intronic chr3:142116856(-) A-I      intronic chr3:142076780(-) A-I      intronic chr3:142042569(-) A-I      intronic chr3:142116965(-) A-I      intronic chr3:142121298(-) A-I      intronic chr3:142035267(-) A-I      intronic chr3:142143210(-) A-I      intronic chr3:142139407(-) A-I      intronic chr3:142135774(-) A-I      intronic chr3:142117489(-) A-I      intronic chr3:142076565(-) A-I      intronic chr3:142110459(-) A-I      intronic chr3:142086516(-) A-I      intronic chr3:142085865(-) A-I      intronic chr3:142079664(-) A-I      intronic chr3:142086536(-) A-I      intronic chr3:142041679(-) A-I      intronic chr3:142135202(-) A-I      intronic chr3:142107840(-) A-I      intronic chr3:142143003(-) A-I      intronic chr3:142116862(-) A-I      intronic chr3:142041446(-) A-I      intronic chr3:142033915(-) A-I      intronic chr3:142076616(-) A-I      intronic chr3:142076361(-) A-I      intronic chr3:142135189(-) A-I      intronic chr3:142120542(-) A-I      intronic chr3:142076768(-) A-I      intronic chr3:142086654(-) A-I      intronic chr3:142041682(-) A-I      intronic chr3:142107854(-) A-I      intronic chr3:142086648(-) A-I      intronic chr3:142050890(-) A-I      intronic chr3:142146978(-) A-I      intronic chr3:142041905(-) A-I      intronic chr3:142042188(-) A-I      intronic chr3:142116849(-) A-I      intronic chr3:142135773(-) A-I      intronic chr3:142035745(-) A-I      intronic chr3:142110374(-) A-I      intronic chr3:142033502(-) A-I      intronic chr3:142035217(-) A-I      intronic chr3:142042274(-) A-I      intronic chr3:142107968(-) A-I      intronic chr3:142041928(-) A-I      intronic chr3:142085864(-) A-I      intronic chr3:142081183(-) A-I      intronic chr3:142133609(-) A-I      intronic chr3:142140992(-) A-I      intronic chr3:142133476(-) A-I      intronic chr3:142041362(-) A-I      intronic chr3:142042642(-) A-I      intronic chr3:142071590(-) A-I      intronic chr3:142135788(-) A-I      intronic chr3:142121297(-) A-I      intronic chr3:142081318(-) A-I      intronic chr3:142033996(-) A-I      intronic chr3:142121163(-) A-I      intronic chr3:142032768(-) A-I      intronic chr3:142135785(-) A-I      intronic chr3:142041929(-) A-I      intronic chr3:142108433(-) A-I      intronic chr3:142079670(-) A-I      intronic chr3:142151244(-) A-I      intronic chr3:142041465(-) A-I      intronic chr3:142138503(-) A-I      intronic chr3:142135252(-) A-I      intronic chr3:142108538(-) A-I      intronic chr3:142112833(-) A-I      intronic chr3:142033901(-) A-I      intronic chr3:142110336(-) A-I      intronic chr3:142134896(-) A-I      intronic chr3:142076366(-) A-I      intronic chr3:142041196(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	XRN1	chr3:142032725(-) A-I intron -    22327324 chr3:142041154(-) A-I intron -    22327324 chr3:142041196(-) A-I intron -    21960545   //22327324 chr3:142041207(-) A-I intron -    21960545   //22327324 chr3:142042590(-) A-I intron -    22327324 chr3:142035692(-) A-I intron -    21960545 chr3:142035693(-) A-I intron -    21960545 chr3:142041204(-) A-I intron -    21960545 chr3:142042640(-) A-I intron -    21960545 chr3:142051005(-) A-I intron -    21960545 chr3:142051070(-) A-I intron -    21960545 chr3:142028317(-) A-G exon 3'UTR    22484847 chr3:142032713(-) A-G intron -    22484847 chr3:142032719(-) A-G intron -    22484847 chr3:142032725(-) A-G intron -    22484847 chr3:142032744(-) A-G intron -    22484847 chr3:142033543(-) A-G intron -    22484847 chr3:142033651(-) A-G intron -    22484847 chr3:142033915(-) A-G intron -    22484847 chr3:142033996(-) A-G intron -    22484847 chr3:142033997(-) A-G intron -    22484847 chr3:142034056(-) A-G intron -    22484847 chr3:142035223(-) A-G intron -    22484847 chr3:142035650(-) A-G intron -    22484847 chr3:142035692(-) A-G intron -    22484847 chr3:142041154(-) A-G intron -    22484847 chr3:142041196(-) A-G intron -    22484847 chr3:142041204(-) A-G intron -    22484847 chr3:142041207(-) A-G intron -    22484847 chr3:142041465(-) A-G intron -    22484847 chr3:142041486(-) A-G intron -    22484847 chr3:142041762(-) A-G intron -    22484847 chr3:142041935(-) A-G intron -    22484847 chr3:142042274(-) A-G intron -    22484847 chr3:142042296(-) A-G intron -    22484847 chr3:142042297(-) A-G intron -    22484847 chr3:142042569(-) A-G intron -    22484847 chr3:142042642(-) A-G intron -    22484847 chr3:142047870(-) T-C intron -    22484847 chr3:142047872(-) A-G intron -    22484847 chr3:142051044(-) A-G intron -    22484847 chr3:142053951(-) T-C intron -    22484847 chr3:142065410(-) G-T intron -    22484847 chr3:142065499(-) A-G intron -    22484847 chr3:142066619(-) G-A intron -    22484847 chr3:142076361(-) A-G intron -    22484847 chr3:142076366(-) A-G intron -    22484847 chr3:142076393(-) A-G intron -    22484847 chr3:142076565(-) A-G intron -    22484847 chr3:142076660(-) A-G intron -    22484847 chr3:142076661(-) A-G intron -    22484847 chr3:142076756(-) A-G intron -    22484847 chr3:142076758(-) A-G intron -    22484847 chr3:142076768(-) A-G intron -    22484847 chr3:142076780(-) A-G intron -    22484847 chr3:142076793(-) A-G intron -    22484847 chr3:142076797(-) A-G intron -    22484847 chr3:142079455(-) G-T intron -    22484847 chr3:142079670(-) A-G intron -    22484847 chr3:142085865(-) A-G intron -    22484847 chr3:142086066(-) A-G intron -    22484847 chr3:142086567(-) A-G intron -    22484847 chr3:142086648(-) A-G intron -    22484847 chr3:142086654(-) A-G intron -    22484847 chr3:142088495(-) A-T intron -    22484847 chr3:142097956(-) A-T intron -    22484847 chr3:142107839(-) A-G intron -    22484847 chr3:142107840(-) A-G intron -    22484847 chr3:142107854(-) A-G intron -    22484847 chr3:142107972(-) A-G intron -    22484847 chr3:142108433(-) A-G intron -    22484847 chr3:142108538(-) A-G intron -    22484847 chr3:142108555(-) A-G intron -    22484847 chr3:142110336(-) A-G intron -    22484847 chr3:142112888(-) A-G intron -    22484847 chr3:142112964(-) A-G intron -    22484847 chr3:142116838(-) A-G intron -    22484847 chr3:142116856(-) A-G intron -    22484847 chr3:142116866(-) A-G intron -    22484847 chr3:142116867(-) A-G intron -    22484847 chr3:142116965(-) A-G intron -    22484847 chr3:142116992(-) A-G intron -    22484847 chr3:142117017(-) A-G intron -    22484847 chr3:142117019(-) A-G intron -    22484847 chr3:142120363(-) A-G intron -    22484847 chr3:142120542(-) A-G intron -    22484847 chr3:142121163(-) A-G intron -    22484847 chr3:142133453(-) A-G intron -    22484847 chr3:142133476(-) A-G intron -    22484847 chr3:142133521(-) A-G intron -    22484847 chr3:142133532(-) A-G intron -    22484847 chr3:142133604(-) A-G intron -    22484847 chr3:142133609(-) A-G intron -    22484847 chr3:142133632(-) A-G intron -    22484847 chr3:142134841(-) A-G intron -    22484847 chr3:142134896(-) A-G intron -    22484847 chr3:142135207(-) A-G intron -    22484847 chr3:142135218(-) A-G intron -    22484847 chr3:142135252(-) A-G intron -    22484847 chr3:142135623(-) A-G intron -    22484847 chr3:142135657(-) A-G intron -    22484847 chr3:142135708(-) A-G intron -    22484847 chr3:142135719(-) A-G intron -    22484847 chr3:142135752(-) A-G intron -    22484847 chr3:142135773(-) A-G intron -    22484847 chr3:142135774(-) A-G intron -    22484847 chr3:142135785(-) A-G intron -    22484847 chr3:142135788(-) A-G intron -    22484847 chr3:142135827(-) A-G intron -    22484847 chr3:142138494(-) A-G intron -    22484847 chr3:142138527(-) A-G intron -    22484847 chr3:142139351(-) A-G intron -    22484847 chr3:142139508(-) A-G intron -    22484847 chr3:142146978(-) A-G intron -    22484847 chr3:142147137(-) A-G intron -    22484847 chr3:142147155(-) A-G intron -    22484847 chr3:142148165(-) A-G intron -    22484847 chr3:142151244(-) A-G intron -    22484847 chr3:142151254(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	XRN1	chr3:142029995-142029996(-) m6A 3'UTR       27773535 chr3:142030007-142030008(-) m6A 3'UTR       27773535 chr3:142030058-142030059(-) m6A 3'UTR       27773535 chr3:142030063-142030064(-) m6A 3'UTR       27773535 chr3:142030097-142030098(-) m6A 3'UTR       27773535 chr3:142030107-142030108(-) m6A 3'UTR       27773535 chr3:142030186-142030187(-) m6A 3'UTR       27773535 chr3:142030576-142030577(-) m6A CDS       24284625//27371828 chr3:142030623-142030624(-) m6A CDS       24284625 chr3:142048341-142048342(-) m6A CDS//exon//intron       27773535 chr3:142048399-142048400(-) m6A CDS//exon//intron       27773535 chr3:142048444-142048445(-) m6A CDS//exon//intron       27773535 chr3:142051232-142051233(-) m6A 3'UTR//CDS//exon       27773535 chr3:142131485-142131486(-) m6A CDS//exon       27773535 chr3:142133033-142133034(-) m6A CDS//exon       27773535 chr3:142133051-142133052(-) m6A CDS//exon       27773535 chr3:142133060-142133061(-) m6A CDS//exon       27773535 chr3:142137385-142137386(-) m6A 3'UTR//CDS//exon       27773535 chr3:142137398-142137399(-) m6A 3'UTR//CDS//exon       24981863//27773535 chr3:142137409-142137410(-) m6A 3'UTR//CDS//exon       24981863//27773535 chr3:142137433-142137434(-) m6A 3'UTR//CDS//exon       24981863//27773535 chr3:142137688-142137689(-) m6A 3'UTR//CDS//exon       24981863//27773535 chr3:142137698-142137699(-) m6A 3'UTR//CDS//exon       24981863//27773535 chr3:142139882-142139883(-) m6A 3'UTR//CDS//exon       24981863//27773535 chr3:142144093-142144094(-) m6A CDS//exon//intron       27773535 chr3:142144100-142144101(-) m6A CDS//exon//intron       27773535 chr3:142145630-142145631(-) m6A 5'UTR//CDS//exon//intron       27773535 chr3:142145662-142145663(-) m6A 5'UTR//CDS//exon//intron       27773535 chr3:142148562-142148563(-) m6A 5'UTR//intron       27773535 chr3:142148588-142148589(-) m6A 5'UTR//intron       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	XRN1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Insoluble cytoplasm K562 cells     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-2-3p
Interactor2: XRN1

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg