Basic Information:

  VIRBase ID:  

VHID00229246

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-2-3p:  MIMAT0001580          ICOS:  NM_012092     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-2-3p	ICOS
miRBase Accession/Entrez ID	MIMAT0001580	29851
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	AILIM//CD278//CVID1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ICOS	chr2:204819237(+) A-I      intronic chr2:204819251(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ICOS	chr2:204815611(+) T-C intron -    22484847 chr2:204815752(+) T-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ICOS	chr2:204824402-204824403(+) m6A 3'UTR       26404942 chr2:204824496-204824497(+) m6A 3'UTR       26404942 chr2:204824526-204824527(+) m6A 3'UTR       26404942 chr2:204824635-204824636(+) m6A 3'UTR       26404942 chr2:204824710-204824711(+) m6A 3'UTR       26404942 chr2:204824838-204824839(+) m6A 3'UTR       26404942 chr2:204824881-204824882(+) m6A 3'UTR       26404942 chr2:204824905-204824906(+) m6A 3'UTR       26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ICOS	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-2-3p
Interactor2: ICOS

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg