Basic Information:

  VIRBase ID:  

VHID00228126

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          TRIM67:  NM_001004342     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	TRIM67
miRBase Accession/Entrez ID	MIMAT0001579	440730
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	TNL

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TRIM67	chr1:231305912(+) A-I      intronic chr1:231333561(+) A-I      intronic chr1:231333859(+) A-I      intronic chr1:231333550(+) A-I      intronic chr1:231303897(+) A-I      intronic chr1:231332128(+) A-I      intronic chr1:231319244(+) A-I      intronic chr1:231303833(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TRIM67	chr1:231299643-231299644(+) m6A CDS       24981863 chr1:231299672-231299673(+) m6A CDS       24981863 chr1:231351429-231351430(+) m6A 3'UTR       24981863 chr1:231351438-231351439(+) m6A 3'UTR       24981863 chr1:231351454-231351455(+) m6A 3'UTR       24981863 chr1:231353760-231353761(+) m6A 3'UTR       24981863 chr1:231353784-231353785(+) m6A 3'UTR       24981863 chr1:231356600-231356601(+) m6A 3'UTR       24981863 chr1:231356825-231356826(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	TRIM67	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: TRIM67

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg