Basic Information:

  VIRBase ID:  

VHID00228086

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          NPSR1:  NM_001300933     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	NPSR1
miRBase Accession/Entrez ID	MIMAT0001579	387129
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ASRT2//GPR154//GPRA//NPSR//PGR14//VRR1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NPSR1	chr7:34791137(+) A-I      intronic chr7:34729580(+) A-I      intronic chr7:34772861(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	NPSR1	chr7:34791139(+) A-I intron -    22327324 chr7:34791148(+) A-I intron -    22327324 chr7:34791149(+) A-I intron -    22327324 chr7:34791151(+) A-I intron -    22327324 chr7:34791154(+) A-I intron -    22327324 chr7:34791398(+) A-I intron -    22327324 chr7:34791584(+) A-I intron -    22327324 chr7:34791597(+) A-I intron -    22327324

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	NPSR1	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: NPSR1

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg