Basic Information:

  VIRBase ID:  

VHID00228070

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          MTX3:  NM_001363818     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	MTX3
miRBase Accession/Entrez ID	MIMAT0001579	345778
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MTX3	chr5:79283767(-) A-I      intronic chr5:79283777(-) A-I      intronic chr5:79283833(-) A-I      intronic chr5:79283859(-) A-I      intronic chr5:79283882(-) A-I      intronic chr5:79280979(-) A-I      intronic chr5:79281076(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MTX3	chr5:79281864(-) A-I intron -    15342557 chr5:79281890(-) A-I intron -    15342557 chr5:79283015(-) A-I intron -    15342557 chr5:79283047(-) A-I intron -    15342557 chr5:79283084(-) A-I intron -    15342557 chr5:79283098(-) A-I intron -    15342557 chr5:79283101(-) A-I intron -    15342557 chr5:79283151(-) A-I intron -    15342557 chr5:79283154(-) A-I intron -    15342557 chr5:79283047(-) A-G intron -    22484847 chr5:79283101(-) A-G intron -    22484847 chr5:79283919(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MTX3	chr5:79275944-79275945(-) Y 3'UTR       26075521 chr5:79276299-79276300(-) m6A 3'UTR       27773535 chr5:79276334-79276335(-) m6A 3'UTR       27773535 chr5:79276360-79276361(-) m6A 3'UTR       27773535 chr5:79279242-79279243(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr5:79279265-79279266(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr5:79279292-79279293(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr5:79279385-79279386(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr5:79279395-79279396(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr5:79279402-79279403(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr5:79279572-79279573(-) m6A 3'UTR//CDS//intron       24284625//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MTX3	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: MTX3

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg