Basic Information:

  VIRBase ID:  

VHID00228069

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          SH3RF3:  NM_001099289     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	SH3RF3
miRBase Accession/Entrez ID	MIMAT0001579	344558
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	POSH2//SH3MD4

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SH3RF3	chr2:110091618(+) A-I      intronic chr2:110258472(+) A-I      intronic chr2:110258482(+) A-I      intronic chr2:110258442(+) A-I      intronic chr2:109868653(+) A-I      intronic chr2:109868650(+) A-I      intronic chr2:109868649(+) A-I      intronic chr2:109784274(+) A-I      intronic chr2:109815637(+) A-I      intronic chr2:109821529(+) A-I      intronic chr2:109846398(+) A-I      intronic chr2:110043608(+) A-I      intronic chr2:110033102(+) A-I      intronic chr2:110087451(+) A-I      intronic chr2:109760000(+) A-I      intronic chr2:109760012(+) A-I      intronic chr2:109760013(+) A-I      intronic chr2:109760063(+) A-I      intronic chr2:109868483(+) A-I      intronic chr2:109782715(+) A-I      intronic chr2:109782723(+) A-I      intronic chr2:109782746(+) A-I      intronic chr2:110032841(+) A-I      intronic chr2:109782893(+) A-I      intronic chr2:109784127(+) A-I      intronic chr2:109784145(+) A-I      intronic chr2:109784229(+) A-I      intronic chr2:109866147(+) A-I      intronic chr2:109856823(+) A-I      intronic chr2:109856698(+) A-I      intronic chr2:110100622(+) A-I      intronic chr2:109846957(+) A-I      intronic chr2:109846956(+) A-I      intronic chr2:109846782(+) A-I      intronic chr2:109846777(+) A-I      intronic chr2:110258461(+) A-I      intronic chr2:110258460(+) A-I      intronic chr2:110106383(+) A-I      intronic chr2:110100623(+) A-I      intronic chr2:109782706(+) A-I      intronic chr2:109772952(+) A-I      intronic chr2:109846410(+) A-I      intronic chr2:110106377(+) A-I      intronic chr2:110032849(+) A-I      intronic chr2:109867639(+) A-I      intronic chr2:109868488(+) A-I      intronic chr2:109868493(+) A-I      intronic chr2:109868579(+) A-I      intronic chr2:109912777(+) A-I      intronic chr2:109973844(+) A-I      intronic chr2:110008345(+) A-I      intronic chr2:109782747(+) A-I      intronic chr2:109782822(+) A-I      intronic chr2:110048242(+) A-I      intronic chr2:109894518(+) A-I      intronic chr2:109983409(+) A-I      intronic chr2:109782786(+) A-I      intronic chr2:109782768(+) A-I      intronic chr2:109868500(+) A-I      intronic chr2:109782751(+) A-I      intronic chr2:109869649(+) A-I      intronic chr2:109846871(+) A-I      intronic chr2:109846768(+) A-I      intronic chr2:110048163(+) A-I      intronic chr2:110087611(+) A-I      intronic chr2:109822893(+) A-I      intronic chr2:109773001(+) A-I      intronic chr2:109821526(+) A-I      intronic chr2:109868443(+) A-I      intronic chr2:109821482(+) A-I      intronic chr2:109867588(+) A-I      intronic chr2:109821532(+) A-I      intronic chr2:109782848(+) A-I      intronic chr2:109782839(+) A-I      intronic chr2:109846778(+) A-I      intronic chr2:109759974(+) A-I      intronic chr2:110258397(+) A-I      intronic chr2:109784157(+) A-I      intronic chr2:109950551(+) A-I      intronic chr2:110033043(+) A-I      intronic chr2:109821809(+) A-I      intronic chr2:110066682(+) A-I      intronic chr2:109846925(+) A-I      intronic chr2:110032944(+) A-I      intronic chr2:109784167(+) A-I      intronic chr2:109846465(+) A-I      intronic chr2:109841186(+) A-I      intronic chr2:109821980(+) A-I      intronic chr2:109865537(+) A-I      intronic chr2:109759966(+) A-I      intronic chr2:109868441(+) A-I      intronic chr2:109868577(+) A-I      intronic chr2:109846487(+) A-I      intronic chr2:109784140(+) A-I      intronic chr2:109841193(+) A-I      intronic chr2:109846945(+) A-I      intronic chr2:109866173(+) A-I      intronic chr2:109822826(+) A-I      intronic chr2:109782883(+) A-I      intronic chr2:109856824(+) A-I      intronic chr2:109815672(+) A-I      intronic chr2:109822759(+) A-I      intronic chr2:109784102(+) A-I      intronic chr2:109846990(+) A-I      intronic chr2:109821821(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SH3RF3	chr2:109784128(+) A-G intron -    22484847 chr2:109784140(+) A-G intron -    22484847 chr2:109784167(+) A-G intron -    22484847 chr2:109784234(+) A-G intron -    22484847 chr2:109815672(+) A-G intron -    22484847 chr2:109821482(+) A-G intron -    22484847 chr2:109821526(+) A-G intron -    22484847 chr2:109821809(+) A-G intron -    22484847 chr2:109821821(+) A-G intron -    22484847 chr2:109821831(+) A-G intron -    22484847 chr2:109841186(+) A-G intron -    22484847 chr2:109841193(+) A-G intron -    22484847 chr2:109846465(+) A-G intron -    22484847 chr2:109846487(+) A-G intron -    22484847 chr2:109846871(+) A-G intron -    22484847 chr2:109846990(+) A-G intron -    22484847 chr2:109856824(+) A-G intron -    22484847 chr2:109879564(+) A-G intron -    22484847 chr2:110033038(+) A-G intron -    22484847 chr2:110033043(+) A-G intron -    22484847 chr2:110033113(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SH3RF3	chr2:109745956-109745957(+) m6A 5'UTR       22575960//22608085 chr2:109745975-109745976(+) m6A 5'UTR       22575960//22608085 chr2:109746069-109746070(+) m6A CDS       24209618//22608085 chr2:109746129-109746130(+) m6A CDS       24209618//25456834//22608085 chr2:109746153-109746154(+) m6A CDS       24209618//25456834//22575960//22608085 chr2:109746189-109746190(+) m6A CDS       24209618//25456834//22575960//22608085 chr2:109746316-109746317(+) m6A CDS       24209618//25456834//24981863//22575960//22608085 chr2:110065652-110065653(+) m6A CDS       24209618//24981863 chr2:110065691-110065692(+) m6A CDS       24209618//24981863 chr2:110259188-110259189(+) m6A CDS       24209618//25456834//24981863 chr2:110259250-110259251(+) m6A 3'UTR       24209618//25456834//24981863 chr2:110259399-110259400(+) m6A 3'UTR       24209618//25456834//24981863 chr2:110259426-110259427(+) m6A 3'UTR       24209618//25456834//24981863 chr2:110259488-110259489(+) m6A 3'UTR       24209618//25456834//24981863 chr2:110261905-110261906(+) m6A 3'UTR       - chr2:110261916-110261917(+) m6A 3'UTR       - chr2:110261921-110261922(+) m6A 3'UTR       - chr2:110262027-110262028(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	SH3RF3	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: SH3RF3

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg