Basic Information:

  VIRBase ID:  

VHID00227987

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          RFX6:  NM_173560     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	RFX6
miRBase Accession/Entrez ID	MIMAT0001579	222546
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	dJ955L16.1//MTCHRS//MTFS//RFXDC1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RFX6	chr6:117221518(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RFX6	chr6:117248416-117248417(+) m6A CDS       24981863//22608085 chr6:117248451-117248452(+) m6A CDS       24981863//22608085 chr6:117248494-117248495(+) m6A CDS       22608085 chr6:117248499-117248500(+) m6A CDS       22608085 chr6:117248516-117248517(+) m6A CDS       22608085 chr6:117250072-117250073(+) m6A CDS       - chr6:117250095-117250096(+) m6A CDS       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	RFX6	Exosome Blood     - Membrane K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: RFX6

Evidence Support:

Prediction-Evidence	miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg