Basic Information:

  VIRBase ID:  

VHID00227940

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          ADAMTS19:  NM_133638     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	ADAMTS19
miRBase Accession/Entrez ID	MIMAT0001579	171019
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ADAMTS19	chr5:129051960(+) A-I      intronic chr5:129013580(+) A-I      intronic chr5:129013689(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ADAMTS19	chr5:129030543-129030544(+) m6A CDS//exon       22608085 chr5:129037099-129037100(+) m6A CDS//exon       24981863//22608085 chr5:129037114-129037115(+) m6A CDS//exon       24981863//22608085 chr5:129037140-129037141(+) m6A CDS//exon       24981863//22608085 chr5:129037174-129037175(+) m6A CDS//exon       24981863//22608085 chr5:129037199-129037200(+) m6A CDS//exon       24981863//22608085 chr5:129072825-129072826(+) m6A CDS       24981863 chr5:129072837-129072838(+) m6A CDS       24981863 chr5:129072866-129072867(+) m6A CDS       24981863 chr5:129072876-129072877(+) m6A CDS       24981863 chr5:129072962-129072963(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ADAMTS19	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: ADAMTS19

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg