Basic Information:

  VIRBase ID:  

VHID00227918

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          ANKRD46:  NM_198401     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	ANKRD46
miRBase Accession/Entrez ID	MIMAT0001579	157567
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ANK-S//GENX-115279

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ANKRD46	chr8:101547155(-) A-I      intronic chr8:101566680(-) A-I      intronic chr8:101561449(-) A-I      intronic chr8:101561425(-) A-I      intronic chr8:101566853(-) A-I      intronic chr8:101543968(-) A-I      intronic chr8:101544000(-) A-I      intronic chr8:101566846(-) A-I      intronic chr8:101547213(-) A-I      intronic chr8:101566701(-) A-I      intronic chr8:101544446(-) A-I      intronic chr8:101567160(-) A-I      intronic chr8:101568468(-) A-I      intronic chr8:101568452(-) A-I      intronic chr8:101566729(-) A-I      intronic chr8:101568530(-) A-I      intronic chr8:101566796(-) A-I      intronic chr8:101566783(-) A-I      intronic chr8:101543996(-) A-I      intronic chr8:101568364(-) A-I      intronic chr8:101544614(-) A-I      5'UTR chr8:101544683(-) A-I      5'UTR chr8:101544634(-) A-I      5'UTR chr8:101544602(-) A-I      5'UTR chr8:101542740(-) A-I      intronic chr8:101568467(-) A-I      intronic chr8:101561471(-) A-I      intronic chr8:101568515(-) A-I      intronic chr8:101547203(-) A-I      intronic chr8:101568381(-) A-I      intronic chr8:101564295(-) A-I      intronic chr8:101542832(-) A-I      intronic chr8:101557387(-) A-I      intronic chr8:101547101(-) A-I      intronic chr8:101544476(-) A-I      intronic chr8:101535368(-) A-I      intronic chr8:101535390(-) A-I      intronic chr8:101568521(-) A-I      intronic chr8:101568539(-) A-I      intronic chr8:101567112(-) A-I      intronic chr8:101568357(-) A-I      intronic chr8:101568448(-) A-I      intronic chr8:101542886(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ANKRD46	chr8:101535287(-) T-C intron -    22484847 chr8:101542708(-) A-G intron -    22484847 chr8:101542832(-) A-G intron -    22484847 chr8:101543996(-) A-G intron -    22484847 chr8:101544446(-) A-G intron -    22484847 chr8:101544683(-) A-G exon 5'UTR    22484847 chr8:101547203(-) A-G intron -    22484847 chr8:101561471(-) A-G intron -    22484847 chr8:101564295(-) A-G intron -    22484847 chr8:101566796(-) A-G intron -    22484847 chr8:101567111(-) A-G intron -    22484847 chr8:101567112(-) A-G intron -    22484847 chr8:101567160(-) A-G intron -    22484847 chr8:101568400(-) A-G intron -    22484847 chr8:101568476(-) A-G intron -    22484847 chr8:101568481(-) A-G intron -    22484847 chr8:101568515(-) A-G intron -    22484847 chr8:101568521(-) A-G intron -    22484847 chr8:101568522(-) A-G intron -    22484847 chr8:101568530(-) A-G intron -    22484847 chr8:101568538(-) A-G intron -    22484847 chr8:101568539(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ANKRD46	chr8:101522140-101522141(-) m6A 3'UTR       27773535 chr8:101522265-101522266(-) m6A 3'UTR       - chr8:101522290-101522291(-) m6A 3'UTR       - chr8:101522411-101522412(-) m6A 3'UTR       - chr8:101522860-101522861(-) m6A CDS       27773535 chr8:101533143-101533144(-) m6A 3'UTR//intron       27773535 chr8:101533781-101533782(-) Y 3'UTR//intron       26075521 chr8:101541885-101541886(-) m6A CDS       24284625//22608085 chr8:101541922-101541923(-) m6A CDS       24284625//24981863//26404942//22608085 chr8:101541990-101541991(-) m6A CDS       24284625//24981863//26404942//22608085 chr8:101542027-101542028(-) m6A CDS       24284625//24981863//26404942//22608085 chr8:101542063-101542064(-) m6A 5'UTR       24284625//22608085 chr8:101544586-101544587(-) m6A 5'UTR//intron       24284625//22608085 chr8:101562822-101562823(-) m6A exon//intron       24284625//24981863//27773535//22608085 chr8:101562903-101562904(-) m6A exon//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr8:101562949-101562950(-) m6A exon//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr8:101563116-101563117(-) m6A exon//intron       24981863//22608085 chr8:101563196-101563197(-) m6A exon//intron       22608085 chr8:101563218-101563219(-) m6A exon//intron       22608085 chr8:101563274-101563275(-) m6A exon//intron       22608085 chr8:101563334-101563335(-) m6A exon//intron       24284625//25456834//24981863//22608085 chr8:101563365-101563366(-) m6A exon//intron       24284625//24209618//25456834//24981863//22608085 chr8:101563386-101563387(-) m6A exon//intron       24284625//24209618//25456834//24981863//22608085 chr8:101563426-101563427(-) m6A exon//intron       24284625//24209618//25456834//24981863//22608085 chr8:101563519-101563520(-) m6A exon//intron       24284625 chr8:101568813-101568814(-) m6A exon//intron       - chr8:101568825-101568826(-) m6A exon//intron       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ANKRD46	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: ANKRD46

Evidence Support:

Prediction-Evidence	cRep//miRanda
Support Database	RepTar//VmiReg