Basic Information:

  VIRBase ID:  

VHID00227823

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          XIRP2:  NM_001199144     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	XIRP2
miRBase Accession/Entrez ID	MIMAT0001579	129446
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CMYA3

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	XIRP2	chr2:168103874(+) A-I      NonSyn:Gln->Arg chr2:168110633(+) A-I      NonSyn:His->Arg chr2:168103881(+) A-I      Syn:Gly->Gly chr2:168103884(+) A-I      Syn:Ala->Ala chr2:168110681(+) A-I      intronic chr2:168110679(+) A-I      intronic chr2:168110680(+) A-I      intronic chr2:168084161(+) A-I      intronic chr2:168036423(+) A-I      intronic chr2:168047709(+) A-I      intronic chr2:167911035(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	XIRP2	chr2:168114760(+) A-I exon 3'UTR    19478186

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	XIRP2	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: XIRP2

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg