Basic Information:

  VIRBase ID:  

VHID00227741

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          MRAP2:  NM_001346541     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	MRAP2
miRBase Accession/Entrez ID	MIMAT0001579	112609
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	bA51G5.2//C6orf117

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MRAP2	chr6:84791309(+) A-I      intronic chr6:84791306(+) A-I      intronic chr6:84791283(+) A-I      intronic chr6:84791282(+) A-I      intronic chr6:84791280(+) A-I      intronic chr6:84756349(+) A-I      intronic chr6:84756313(+) A-I      intronic chr6:84773541(+) A-I      intronic chr6:84774413(+) A-I      intronic chr6:84756353(+) A-I      intronic chr6:84756245(+) A-I      intronic chr6:84757154(+) A-I      intronic chr6:84757185(+) A-I      intronic chr6:84761399(+) A-I      intronic chr6:84757176(+) A-I      intronic chr6:84756323(+) A-I      intronic chr6:84757110(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MRAP2	chr6:84798961-84798962(+) m6A CDS       25456834//24981863//22608085 chr6:84798984-84798985(+) m6A CDS       25456834//24981863//22608085 chr6:84799057-84799058(+) m6A CDS       25456834//24981863//22608085 chr6:84799093-84799094(+) m6A CDS       25456834//24981863//22608085 chr6:84799099-84799100(+) m6A CDS       25456834//24981863//22608085 chr6:84799105-84799106(+) m6A CDS       25456834//24981863//22608085 chr6:84799139-84799140(+) m6A CDS       25456834//24981863//22608085 chr6:84799158-84799159(+) m6A CDS       25456834//24981863//22608085 chr6:84799176-84799177(+) m6A CDS       25456834//24981863//22608085 chr6:84799189-84799190(+) m6A CDS       25456834//24981863//22608085 chr6:84799203-84799204(+) m6A 3'UTR       25456834//24981863//22608085 chr6:84799302-84799303(+) m6A 3'UTR       22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MRAP2	Chromatin K562 cells     - Cytosol K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: MRAP2

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg