Basic Information:

  VIRBase ID:  

VHID00227630

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          PSD2:  NM_032289     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	PSD2
miRBase Accession/Entrez ID	MIMAT0001579	84249
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	EFA6C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PSD2	chr5:139200657(+) A-I      intronic chr5:139198065(+) A-I      intronic chr5:139180069(+) A-I      intronic chr5:139198046(+) A-I      intronic chr5:139195458(+) A-I      intronic chr5:139197948(+) A-I      intronic chr5:139198051(+) A-I      intronic chr5:139197972(+) A-I      intronic chr5:139200618(+) A-I      intronic chr5:139200598(+) A-I      intronic chr5:139180528(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PSD2	chr5:139189143-139189144(+) m6A CDS       - chr5:139189191-139189192(+) m6A CDS       25456834 chr5:139189201-139189202(+) m6A CDS       25456834 chr5:139189212-139189213(+) m6A CDS       25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PSD2	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: PSD2

Evidence Support:

Prediction-Evidence	miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg