Basic Information:

  VIRBase ID:  

VHID00227372

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          RAB22A:  NM_020673     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	RAB22A
miRBase Accession/Entrez ID	MIMAT0001579	57403
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RAB22A	chr20:56889209(+) A-I      intronic chr20:56913273(+) A-I      intronic chr20:56933717(+) A-I      intronic chr20:56933963(+) A-I      intronic chr20:56889124(+) A-I      intronic chr20:56887753(+) A-I      intronic chr20:56887822(+) A-I      intronic chr20:56889635(+) A-I      intronic chr20:56889735(+) A-I      intronic chr20:56904361(+) A-I      intronic chr20:56904316(+) A-I      intronic chr20:56899776(+) A-I      intronic chr20:56899721(+) A-I      intronic chr20:56899716(+) A-I      intronic chr20:56899714(+) A-I      intronic chr20:56889721(+) A-I      intronic chr20:56899713(+) A-I      intronic chr20:56899647(+) A-I      intronic chr20:56895880(+) A-I      intronic chr20:56895854(+) A-I      intronic chr20:56893159(+) A-I      intronic chr20:56892943(+) A-I      intronic chr20:56892937(+) A-I      intronic chr20:56892714(+) A-I      intronic chr20:56892327(+) A-I      intronic chr20:56889854(+) A-I      intronic chr20:56904371(+) A-I      intronic chr20:56892292(+) A-I      intronic chr20:56913183(+) A-I      intronic chr20:56889884(+) A-I      intronic chr20:56889816(+) A-I      intronic chr20:56887076(+) A-I      intronic chr20:56902113(+) A-I      intronic chr20:56896905(+) A-I      intronic chr20:56889817(+) A-I      intronic chr20:56889818(+) A-I      intronic chr20:56900112(+) A-I      intronic chr20:56913266(+) A-I      intronic chr20:56913257(+) A-I      intronic chr20:56940739(+) A-I      3'UTR chr20:56902108(+) A-I      intronic chr20:56896081(+) A-I      intronic chr20:56913222(+) A-I      intronic chr20:56896264(+) A-I      intronic chr20:56889161(+) A-I      intronic chr20:56896926(+) A-I      intronic chr20:56889304(+) A-I      intronic chr20:56893005(+) A-I      intronic chr20:56913334(+) A-I      intronic chr20:56913182(+) A-I      intronic chr20:56913187(+) A-I      intronic chr20:56902114(+) A-I      intronic chr20:56889736(+) A-I      intronic chr20:56896969(+) A-I      intronic chr20:56889737(+) A-I      intronic chr20:56903262(+) A-I      intronic chr20:56889166(+) A-I      intronic chr20:56889355(+) A-I      intronic chr20:56889310(+) A-I      intronic chr20:56913294(+) A-I      intronic chr20:56903372(+) A-I      intronic chr20:56889204(+) A-I      intronic chr20:56913157(+) A-I      intronic chr20:56896995(+) A-I      intronic chr20:56896936(+) A-I      intronic chr20:56913293(+) A-I      intronic chr20:56913263(+) A-I      intronic chr20:56889720(+) A-I      intronic chr20:56893012(+) A-I      intronic chr20:56896950(+) A-I      intronic chr20:56896125(+) A-I      intronic chr20:56889776(+) A-I      intronic chr20:56913152(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RAB22A	chr20:56913152(+) A-I intron -    15342557 chr20:56913157(+) A-I intron -    15342557 chr20:56913182(+) A-I intron -    15342557 chr20:56913183(+) A-I intron -    15342557 chr20:56913187(+) A-I intron -    15342557 chr20:56913212(+) A-I intron -    15342557 chr20:56913216(+) A-I intron -    15342557 chr20:56913222(+) A-I intron -    15342557 chr20:56913257(+) A-I intron -    15342557 chr20:56913263(+) A-I intron -    15342557 chr20:56913266(+) A-I intron -    15342557 chr20:56913293(+) A-I intron -    15342557 chr20:56913334(+) A-I intron -    15342557 chr20:56914558(+) A-I intron -    15342557 chr20:56916094(+) A-I intron -    15342557 chr20:56896950(+) A-G intron -    22484847 chr20:56926617(+) C-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RAB22A	chr20:56884871-56884872(+) m6A 5'UTR//exon       24209618//24981863 chr20:56884880-56884881(+) m6A 5'UTR//exon       24209618//24981863 chr20:56884920-56884921(+) m6A 5'UTR//exon       24209618 chr20:56884994-56884995(+) Y 5'UTR//exon       26075521 chr20:56934716-56934717(+) m6A CDS       24284625//24209618//24981863//22608085 chr20:56934725-56934726(+) m6A CDS       24284625//24209618//24981863//22608085 chr20:56934763-56934764(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr20:56934778-56934779(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr20:56934894-56934895(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr20:56934914-56934915(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr20:56934942-56934943(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr20:56934979-56934980(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr20:56935014-56935015(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr20:56935128-56935129(+) m6A 3'UTR       24981863//22608085 chr20:56935228-56935229(+) m6A 3'UTR       27773535 chr20:56941639-56941640(+) m6A 3'UTR       24981863 chr20:56941681-56941682(+) m6A 3'UTR       24981863 chr20:56941699-56941700(+) m6A 3'UTR       24981863 chr20:56941715-56941716(+) m6A 3'UTR       24981863 chr20:56941741-56941742(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	RAB22A	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: RAB22A

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg