Basic Information:

  VIRBase ID:  

VHID00227337

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          PMEPA1:  NM_199169     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	PMEPA1
miRBase Accession/Entrez ID	MIMAT0001579	56937
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	STAG1//TMEPAI

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PMEPA1	chr20:56240944(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PMEPA1	chr20:56223803-56223804(-) m6A 3'UTR       26404942 chr20:56223861-56223862(-) m6A 3'UTR       26404942 chr20:56224038-56224039(-) m6A 3'UTR       - chr20:56226245-56226246(-) m6A 3'UTR       - chr20:56227061-56227062(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27371828//22608085 chr20:56227120-56227121(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22608085 chr20:56227129-56227130(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22608085 chr20:56227197-56227198(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//27773536//22575960//22608085 chr20:56227404-56227405(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085 chr20:56227409-56227410(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085 chr20:56227436-56227437(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085 chr20:56227441-56227442(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085 chr20:56227460-56227461(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085 chr20:56250930-56250931(-) Cm intron       - chr20:56280082-56280083(-) Am intron       - chr20:56284787-56284788(-) m6A 5'UTR//intron       24209618//27773536 chr20:56285526-56285527(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//27371828//27773536 chr20:56285541-56285542(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//27371828 chr20:56285552-56285553(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//27371828 chr20:56286436-56286437(-) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//22608085 chr20:56286502-56286503(-) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//22608085 chr20:56286541-56286542(-) m6A 5'UTR//exon       24284625//24209618//25456834//24981863 chr20:56286560-56286561(-) m6A 5'UTR//exon       24209618//25456834//24981863 chr20:56286587-56286588(-) m6A 5'UTR//exon       24209618//25456834//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PMEPA1	Cytosol HeLa-S3 cells     - Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: PMEPA1

Evidence Support:

Prediction-Evidence	cRep//miRanda//Targetscan
Support Database	RepTar//VmiReg