Basic Information:

  VIRBase ID:  

VHID00227195

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          NUP62CL:  NR_033676     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	NUP62CL
miRBase Accession/Entrez ID	MIMAT0001579	54830
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NUP62CL	chrX:106375786(-) A-I      intronic chrX:106377085(-) A-I      intronic chrX:106377086(-) A-I      intronic chrX:106386662(-) A-I      intronic chrX:106432981(-) A-I      intronic chrX:106375771(-) A-I      intronic chrX:106375801(-) A-I      intronic chrX:106429980(-) A-I      intronic chrX:106430028(-) A-I      intronic chrX:106375949(-) A-I      intronic chrX:106430041(-) A-I      intronic chrX:106375953(-) A-I      intronic chrX:106375942(-) A-I      intronic chrX:106435707(-) A-I      intronic chrX:106430106(-) A-I      intronic chrX:106430113(-) A-I      intronic chrX:106375863(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	NUP62CL	chrX:106375228(-) A-I intron -    22327324

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NUP62CL	chrX:106367045-106367046(-) m6A 3'UTR       24981863//27773535 chrX:106436266-106436267(-) m6A 5'UTR//intron       24981863 chrX:106449530-106449531(-) m6A 5'UTR       24981863 chrX:106449587-106449588(-) m6A 5'UTR       24981863 chrX:106449634-106449635(-) m6A 5'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	NUP62CL	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: NUP62CL

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg