Detail Information

Basic Information:


  VIRBase ID:  

VHID00226571

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:           AP1S2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US5-1 AP1S2
miRBase
Accession/Entrez ID		 MIMAT0001579 8905
Organism Human betaherpesvirus 5 (HHV-5) Homo sapiens
Category miRNA mRNA
Alias - DC22//MRX59//MRXS21//MRXS5//MRXSF//PGS//SIGMA1B

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR AP1S2
chrX:15855169(-) A-I      intronic
chrX:15855161(-) A-I      intronic
chrX:15855149(-) A-I      intronic
chrX:15861067(-) A-I      intronic
chrX:15854994(-) A-I      intronic
chrX:15852896(-) A-I      intronic
chrX:15854774(-) A-I      intronic
chrX:15854821(-) A-I      intronic
chrX:15854838(-) A-I      intronic
chrX:15854912(-) A-I      intronic
chrX:15854925(-) A-I      intronic
chrX:15855002(-) A-I      intronic
chrX:15856933(-) A-I      intronic
chrX:15857053(-) A-I      intronic
chrX:15857049(-) A-I      intronic
chrX:15857039(-) A-I      intronic
chrX:15860981(-) A-I      intronic
chrX:15861011(-) A-I      intronic
chrX:15860922(-) A-I      intronic
chrX:15860935(-) A-I      intronic
chrX:15860907(-) A-I      intronic
chrX:15854835(-) A-I      intronic
chrX:15854986(-) A-I      intronic
chrX:15852723(-) A-I      intronic
chrX:15856001(-) A-I      intronic
chrX:15860969(-) A-I      intronic
chrX:15861041(-) A-I      intronic
chrX:15854760(-) A-I      intronic
chrX:15857857(-) A-I      intronic
chrX:15854877(-) A-I      intronic
chrX:15857067(-) A-I      intronic
chrX:15857116(-) A-I      intronic
chrX:15857773(-) A-I      intronic
chrX:15855129(-) A-I      intronic
chrX:15855158(-) A-I      intronic
chrX:15852881(-) A-I      intronic
chrX:15854793(-) A-I      intronic
chrX:15857883(-) A-I      intronic
chrX:15854859(-) A-I      intronic
chrX:15854834(-) A-I      intronic
chrX:15861111(-) A-I      intronic
chrX:15854885(-) A-I      intronic
chrX:15854761(-) A-I      intronic
chrX:15854945(-) A-I      intronic
chrX:15856000(-) A-I      intronic
chrX:15857732(-) A-I      intronic
chrX:15857892(-) A-I      intronic
chrX:15854982(-) A-I      intronic
chrX:15860946(-) A-I      intronic
chrX:15860977(-) A-I      intronic
chrX:15855135(-) A-I      intronic
chrX:15860944(-) A-I      intronic
chrX:15852763(-) A-I      intronic
chrX:15857009(-) A-I      intronic
chrX:15860908(-) A-I      intronic
chrX:15857884(-) A-I      intronic
chrX:15861130(-) A-I      intronic
chrX:15861063(-) A-I      intronic
chrX:15854924(-) A-I      intronic
chrX:15861040(-) A-I      intronic
chrX:15861086(-) A-I      intronic
chrX:15855936(-) A-I      intronic
chrX:15857098(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED AP1S2
chrX:15855936(-) A-I intron -    15342557
chrX:15856967(-) A-I intron -    15342557
chrX:15857059(-) A-I intron -    15342557
chrX:15857067(-) A-I intron -    15342557
chrX:15857736(-) A-I intron -    15342557
chrX:15857742(-) A-I intron -    15342557
chrX:15860834(-) A-I intron -    15342557
chrX:15860977(-) A-I intron -    15342557
chrX:15861025(-) A-I intron -    15342557
chrX:15861027(-) A-I intron -    15342557
chrX:15861086(-) A-I intron -    15342557
chrX:15861130(-) A-I intron -    15342557
chrX:15854835(-) A-I intron -    22327324
chrX:15855135(-) A-I intron -    22327324
chrX:15854747(-) A-G intron -    22484847
chrX:15854759(-) A-G intron -    22484847
chrX:15854760(-) A-G intron -    22484847
chrX:15854761(-) A-G intron -    22484847
chrX:15854835(-) A-G intron -    22484847
chrX:15854924(-) A-G intron -    22484847
chrX:15854986(-) A-G intron -    22484847
chrX:15855135(-) A-G intron -    22484847
chrX:15855159(-) A-G intron -    22484847
chrX:15857009(-) A-G intron -    22484847
chrX:15857017(-) A-G intron -    22484847
chrX:15857742(-) A-G intron -    22484847
chrX:15857884(-) A-G intron -    22484847
chrX:15861027(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase AP1S2
chrX:15844139-15844140(-) Y 3'UTR       26075521
chrX:15870576-15870577(-) m6A CDS       24209618

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate AP1S2
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug hcmv-miR-US5-1
Panobinostat       6918837
Irinotecan       60838
Topotecan       60700
l-685,458       5479543
Palbociclib       5330286
Sorafenib       216239
5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120
Dovitinib       135398510
Crizotinib       11626560

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US5-1
Interactor2: AP1S2

Evidence Support:


Prediction-Evidence cRep//miRanda//Targetscan
Support Database RepTar//VmiReg

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