Detail Information

Basic Information:


  VIRBase ID:  

VHID00226399

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:           SPOCK1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US5-1 SPOCK1
miRBase
Accession/Entrez ID		 MIMAT0001579 6695
Organism Human betaherpesvirus 5 (HHV-5) Homo sapiens
Category miRNA mRNA
Alias - SPOCK//TESTICAN//TIC1

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SPOCK1
chr5:136770261(-) A-I      intronic
chr5:136400773(-) A-I      intronic
chr5:136400779(-) A-I      intronic
chr5:136402010(-) A-I      intronic
chr5:136688975(-) A-I      intronic
chr5:136691010(-) A-I      intronic
chr5:136690716(-) A-I      intronic
chr5:136690730(-) A-I      intronic
chr5:136691077(-) A-I      intronic
chr5:136691104(-) A-I      intronic
chr5:136737219(-) A-I      intronic
chr5:136770385(-) A-I      intronic
chr5:136400760(-) A-I      intronic
chr5:136400754(-) A-I      intronic
chr5:136400751(-) A-I      intronic
chr5:136400745(-) A-I      intronic
chr5:136400712(-) A-I      intronic
chr5:136770300(-) A-I      intronic
chr5:136760270(-) A-I      intronic
chr5:136770314(-) A-I      intronic
chr5:136770317(-) A-I      intronic
chr5:136770408(-) A-I      intronic
chr5:136770424(-) A-I      intronic
chr5:136771734(-) A-I      intronic
chr5:136818922(-) A-I      intronic
chr5:136818927(-) A-I      intronic
chr5:136818983(-) A-I      intronic
chr5:136818984(-) A-I      intronic
chr5:136644708(-) A-I      intronic
chr5:136644709(-) A-I      intronic
chr5:136644710(-) A-I      intronic
chr5:136644729(-) A-I      intronic
chr5:136644734(-) A-I      intronic
chr5:136690810(-) A-I      intronic
chr5:136566787(-) A-I      intronic
chr5:136771717(-) A-I      intronic
chr5:136688886(-) A-I      intronic
chr5:136783680(-) A-I      intronic
chr5:136771841(-) A-I      intronic
chr5:136770353(-) A-I      intronic
chr5:136606634(-) A-I      intronic
chr5:136770462(-) A-I      intronic
chr5:136771790(-) A-I      intronic
chr5:136770285(-) A-I      intronic
chr5:136770326(-) A-I      intronic
chr5:136771587(-) A-I      intronic
chr5:136811514(-) A-I      intronic
chr5:136737175(-) A-I      intronic
chr5:136402109(-) A-I      intronic
chr5:136770356(-) A-I      intronic
chr5:136698190(-) A-I      intronic
chr5:136566985(-) A-I      intronic
chr5:136771737(-) A-I      intronic
chr5:136401895(-) A-I      intronic
chr5:136737399(-) A-I      intronic
chr5:136771838(-) A-I      intronic
chr5:136770265(-) A-I      intronic
chr5:136740380(-) A-I      intronic
chr5:136812519(-) A-I      intronic
chr5:136698198(-) A-I      intronic
chr5:136771723(-) A-I      intronic
chr5:136770463(-) A-I      intronic
chr5:136566958(-) A-I      intronic
chr5:136812514(-) A-I      intronic
chr5:136771833(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SPOCK1
chr5:136312646-136312647(-) m6A 3'UTR       24981863
chr5:136312674-136312675(-) m6A 3'UTR       24981863
chr5:136312705-136312706(-) m6A 3'UTR       24981863
chr5:136314205-136314206(-) m6A 3'UTR//exon       24209618//24981863
chr5:136314268-136314269(-) m6A 3'UTR//exon       24209618//24981863
chr5:136314324-136314325(-) m6A 3'UTR//exon       24209618//25456834//24981863
chr5:136314439-136314440(-) m6A CDS//exon       24284625//24209618//25456834//24981863
chr5:136314447-136314448(-) m6A CDS//exon       24284625//24209618//25456834//24981863
chr5:136314518-136314519(-) m6A CDS//exon       24209618//24981863
chr5:136315039-136315040(-) m6A CDS//exon       24209618//24981863
chr5:136315073-136315074(-) m6A CDS//exon       24209618
chr5:136834128-136834129(-) m6A CDS//intron       27773536
chr5:136834885-136834886(-) m6A 5'UTR//intron       24209618//24981863//27773536
chr5:136834893-136834894(-) m6A 5'UTR//intron       24209618//24981863//27773536
chr5:136841354-136841355(-) m6A exon       24981863
chr5:136841360-136841361(-) m6A exon       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate SPOCK1
Cytosol HeLa-S3 cells     -
Exosome Blood     -
Nucleus HeLa-S3 cells|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug hcmv-miR-US5-1
Panobinostat       6918837
Irinotecan       60838
Topotecan       60700
l-685,458       5479543
Palbociclib       5330286
Sorafenib       216239
5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120
Dovitinib       135398510
Crizotinib       11626560

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US5-1
Interactor2: SPOCK1

Evidence Support:


Prediction-Evidence cRep//miRanda//PITA//Rep//Targetscan
Support Database RepTar//VmiReg

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