Basic Information:

  VIRBase ID:  

VHID00226398

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          SPIB:  NM_001243999     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	SPIB
miRBase Accession/Entrez ID	MIMAT0001579	6689
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	SPI-B

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SPIB	chr19:50929850(+) A-I      intronic chr19:50929939(+) A-I      intronic chr19:50929880(+) A-I      intronic chr19:50929896(+) A-I      intronic chr19:50929346(+) A-I      intronic chr19:50927923(+) A-I      intronic chr19:50927946(+) A-I      intronic chr19:50928203(+) A-I      intronic chr19:50928523(+) A-I      intronic chr19:50929974(+) A-I      intronic chr19:50928815(+) A-I      intronic chr19:50928827(+) A-I      intronic chr19:50928839(+) A-I      intronic chr19:50929932(+) A-I      intronic chr19:50928975(+) A-I      intronic chr19:50929290(+) A-I      intronic chr19:50929301(+) A-I      intronic chr19:50929316(+) A-I      intronic chr19:50929355(+) A-I      intronic chr19:50929453(+) A-I      intronic chr19:50929913(+) A-I      intronic chr19:50930222(+) A-I      intronic chr19:50930272(+) A-I      intronic chr19:50930643(+) A-I      intronic chr19:50927776(+) A-I      intronic chr19:50927891(+) A-I      intronic chr19:50928524(+) A-I      intronic chr19:50927679(+) A-I      intronic chr19:50929815(+) A-I      intronic chr19:50929426(+) A-I      intronic chr19:50930620(+) A-I      intronic chr19:50929877(+) A-I      intronic chr19:50929208(+) A-I      intronic chr19:50927725(+) A-I      intronic chr19:50929210(+) A-I      intronic chr19:50929987(+) A-I      intronic chr19:50928831(+) A-I      intronic chr19:50930125(+) A-I      intronic chr19:50928969(+) A-I      intronic chr19:50930032(+) A-I      intronic chr19:50927917(+) A-I      intronic chr19:50927959(+) A-I      intronic chr19:50930172(+) A-I      intronic chr19:50929868(+) A-I      intronic chr19:50929876(+) A-I      intronic chr19:50928364(+) A-I      intronic chr19:50930769(+) A-I      intronic chr19:50928845(+) A-I      intronic chr19:50928881(+) A-I      intronic chr19:50929935(+) A-I      intronic chr19:50930306(+) A-I      intronic chr19:50930185(+) A-I      intronic chr19:50930244(+) A-I      intronic chr19:50928883(+) A-I      intronic chr19:50930634(+) A-I      intronic chr19:50928409(+) A-I      intronic chr19:50927648(+) A-I      intronic chr19:50930661(+) A-I      intronic chr19:50929938(+) A-I      intronic chr19:50927649(+) A-I      intronic chr19:50928837(+) A-I      intronic chr19:50928363(+) A-I      intronic chr19:50927947(+) A-I      intronic chr19:50930131(+) A-I      intronic chr19:50927694(+) A-I      intronic chr19:50930266(+) A-I      intronic chr19:50927877(+) A-I      intronic chr19:50927895(+) A-I      intronic chr19:50928393(+) A-I      intronic chr19:50928775(+) A-I      intronic chr19:50928973(+) A-I      intronic chr19:50930727(+) A-I      intronic chr19:50927684(+) A-I      intronic chr19:50929351(+) A-I      intronic chr19:50930260(+) A-I      intronic chr19:50929961(+) A-I      intronic chr19:50930224(+) A-I      intronic chr19:50930205(+) A-I      intronic chr19:50928888(+) A-I      intronic chr19:50928446(+) A-I      intronic chr19:50928118(+) A-I      intronic chr19:50930726(+) A-I      intronic chr19:50927829(+) A-I      intronic chr19:50928420(+) A-I      intronic chr19:50929820(+) A-I      intronic chr19:50927983(+) A-I      intronic chr19:50928443(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SPIB	chr19:50933106(+) G-A intron -    21725310 chr19:50927829(+) A-G intron -    22484847 chr19:50927862(+) A-G intron -    22484847 chr19:50927895(+) A-G intron -    22484847 chr19:50927917(+) A-G intron -    22484847 chr19:50927947(+) A-G intron -    22484847 chr19:50927959(+) A-G intron -    22484847 chr19:50927983(+) A-G intron -    22484847 chr19:50928173(+) A-G intron -    22484847 chr19:50929426(+) A-G intron -    22484847 chr19:50930125(+) A-G intron -    22484847 chr19:50930185(+) A-G intron -    22484847 chr19:50930244(+) A-G intron -    22484847 chr19:50930661(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SPIB	chr19:50931351-50931352(+) m6A 3'UTR//CDS       25456834 chr19:50931421-50931422(+) m6A 3'UTR//CDS       25456834 chr19:50931456-50931457(+) m6A 3'UTR//CDS       - chr19:50931501-50931502(+) m6A 3'UTR//CDS       - chr19:50931512-50931513(+) m6A 3'UTR//CDS       - chr19:50931822-50931823(+) m6A 3'UTR       25456834//24981863 chr19:50931855-50931856(+) m6A 3'UTR       25456834//24981863 chr19:50931863-50931864(+) m6A 3'UTR       25456834//24981863 chr19:50931990-50931991(+) m6A 3'UTR       25456834 chr19:50933538-50933539(+) m6A 3'UTR       25456834 chr19:50933558-50933559(+) m6A 3'UTR       25456834 chr19:50933989-50933990(+) m6A 3'UTR       - chr19:50934010-50934011(+) m6A 3'UTR       - chr19:50934100-50934101(+) m6A 3'UTR       - chr19:50934155-50934156(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	SPIB	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: SPIB

Evidence Support:

Prediction-Evidence	cRep//Targetscan
Support Database	RepTar//VmiReg