Basic Information:

  VIRBase ID:  

VHID00226209

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:  MIMAT0001579          MME:  NM_000902     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-1	MME
miRBase Accession/Entrez ID	MIMAT0001579	4311
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CALLA//CD10//CMT2T//NEP//SCA43//SFE

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MME	chr3:154803582(+) A-I      intronic chr3:154825063(+) A-I      intronic chr3:154870555(+) A-I      intronic chr3:154814563(+) A-I      intronic chr3:154814637(+) A-I      intronic chr3:154811487(+) A-I      intronic chr3:154814568(+) A-I      intronic chr3:154811524(+) A-I      intronic chr3:154816224(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MME	chr3:154797679-154797680(+) m6A 5'UTR//intron       - chr3:154898280-154898281(+) m6A 3'UTR//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MME	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-US5-1	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Sorafenib       216239 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-1
Interactor2: MME

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg