Detail Information

Basic Information:


  VIRBase ID:  

VHID00225951

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-1:           CHUK:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US5-1 CHUK
miRBase
Accession/Entrez ID		 MIMAT0001579 1147
Organism Human betaherpesvirus 5 (HHV-5) Homo sapiens
Category miRNA mRNA
Alias - IKBKA//IKK-alpha//IKK1//IKKA//NFKBIKA//TCF16

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CHUK
chr10:101971736(-) A-I      intronic
chr10:101983246(-) A-I      intronic
chr10:101981559(-) A-I      intronic
chr10:101968034(-) A-I      intronic
chr10:101973070(-) A-I      intronic
chr10:101983283(-) A-I      intronic
chr10:101983208(-) A-I      intronic
chr10:101971816(-) A-I      intronic
chr10:101981583(-) A-I      intronic
chr10:101981688(-) A-I      intronic
chr10:101984771(-) A-I      intronic
chr10:101981594(-) A-I      intronic
chr10:101983247(-) A-I      intronic
chr10:101957550(-) A-I      intronic
chr10:101981588(-) A-I      intronic
chr10:101968043(-) A-I      intronic
chr10:101968481(-) A-I      intronic
chr10:101972994(-) A-I      intronic
chr10:101977510(-) A-I      intronic
chr10:101971807(-) A-I      intronic
chr10:101968041(-) A-I      intronic
chr10:101967925(-) A-I      intronic
chr10:101971732(-) A-I      intronic
chr10:101968535(-) A-I      intronic
chr10:101968010(-) A-I      intronic
chr10:101962678(-) A-I      intronic
chr10:101973093(-) A-I      intronic
chr10:101968302(-) A-I      intronic
chr10:101967961(-) A-I      intronic
chr10:101968410(-) A-I      intronic
chr10:101968394(-) A-I      intronic
chr10:101973072(-) A-I      intronic
chr10:101988351(-) A-I      intronic
chr10:101973521(-) A-I      intronic
chr10:101949650(-) A-I      intronic
chr10:101973035(-) A-I      intronic
chr10:101968480(-) A-I      intronic
chr10:101968135(-) A-I      intronic
chr10:101965515(-) A-I      intronic
chr10:101971737(-) A-I      intronic
chr10:101988378(-) A-I      intronic
chr10:101973458(-) A-I      intronic
chr10:101973119(-) A-I      intronic
chr10:101967966(-) A-I      intronic
chr10:101967892(-) A-I      intronic
chr10:101973472(-) A-I      intronic
chr10:101973482(-) A-I      intronic
chr10:101968378(-) A-I      intronic
chr10:101973417(-) A-I      intronic
chr10:101956233(-) A-I      intronic
chr10:101968114(-) A-I      intronic
chr10:101973066(-) A-I      intronic
chr10:101988404(-) A-I      intronic
chr10:101988166(-) A-I      intronic
chr10:101968136(-) A-I      intronic
chr10:101971804(-) A-I      intronic
chr10:101988167(-) A-I      intronic
chr10:101981533(-) A-I      intronic
chr10:101976384(-) A-I      intronic
chr10:101971810(-) A-I      intronic
chr10:101957562(-) A-I      intronic
chr10:101973411(-) A-I      intronic
chr10:101968393(-) A-I      intronic
chr10:101973012(-) A-I      intronic
chr10:101968118(-) A-I      intronic
chr10:101973180(-) A-I      intronic
chr10:101968028(-) A-I      intronic
chr10:101972596(-) A-I      intronic
chr10:101973346(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED CHUK
chr10:101968481(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CHUK
chr10:101985771-101985772(-) m6A CDS       24209618//27371828//27773536
chr10:101989315-101989316(-) m6A 5'UTR       24981863//27371828//27773536
chr10:101989326-101989327(-) m6A 5'UTR       24981863//27371828//27773536
chr10:101989338-101989339(-) m6A 5'UTR       24981863//27371828//27773536
chr10:101989368-101989369(-) m6A 5'UTR       24981863//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate CHUK
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug hcmv-miR-US5-1
Panobinostat       6918837
Irinotecan       60838
Topotecan       60700
l-685,458       5479543
Palbociclib       5330286
Sorafenib       216239
5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120
Dovitinib       135398510
Crizotinib       11626560

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US5-1
Interactor2: CHUK

Evidence Support:


Prediction-Evidence cRep//miRanda//Targetscan
Support Database RepTar//VmiReg

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