Basic Information:

  VIRBase ID:  

VHID00224984

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL148D:  MIMAT0001578          PREX1:  NM_020820     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL148D	PREX1
miRBase Accession/Entrez ID	MIMAT0001578	57580
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	P-REX1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PREX1	chr20:47260344(-) A-I      intronic chr20:47260340(-) A-I      intronic chr20:47259859(-) A-I      intronic chr20:47292467(-) A-I      intronic chr20:47427261(-) A-I      intronic chr20:47427202(-) A-I      intronic chr20:47427165(-) A-I      intronic chr20:47427162(-) A-I      intronic chr20:47318708(-) A-I      intronic chr20:47318689(-) A-I      intronic chr20:47318513(-) A-I      intronic chr20:47317889(-) A-I      intronic chr20:47317858(-) A-I      intronic chr20:47314149(-) A-I      intronic chr20:47314021(-) A-I      intronic chr20:47292534(-) A-I      intronic chr20:47292518(-) A-I      intronic chr20:47292463(-) A-I      intronic chr20:47264633(-) A-I      intronic chr20:47264605(-) A-I      intronic chr20:47264587(-) A-I      intronic chr20:47263915(-) A-I      intronic chr20:47263170(-) A-I      intronic chr20:47260466(-) A-I      intronic chr20:47260442(-) A-I      intronic chr20:47260390(-) A-I      intronic chr20:47260356(-) A-I      intronic chr20:47260317(-) A-I      intronic chr20:47260308(-) A-I      intronic chr20:47260234(-) A-I      intronic chr20:47259992(-) A-I      intronic chr20:47259920(-) A-I      intronic chr20:47259895(-) A-I      intronic chr20:47357635(-) A-I      intronic chr20:47259944(-) A-I      intronic chr20:47401562(-) A-I      intronic chr20:47427843(-) A-I      intronic chr20:47409689(-) A-I      intronic chr20:47426875(-) A-I      intronic chr20:47427179(-) A-I      intronic chr20:47318528(-) A-I      intronic chr20:47260349(-) A-I      intronic chr20:47259925(-) A-I      intronic chr20:47263029(-) A-I      intronic chr20:47263931(-) A-I      intronic chr20:47379417(-) A-I      intronic chr20:47260392(-) A-I      intronic chr20:47259827(-) A-I      intronic chr20:47379378(-) A-I      intronic chr20:47260408(-) A-I      intronic chr20:47259841(-) A-I      intronic chr20:47318047(-) A-I      intronic chr20:47264601(-) A-I      intronic chr20:47260350(-) A-I      intronic chr20:47379239(-) A-I      intronic chr20:47260397(-) A-I      intronic chr20:47259752(-) A-I      intronic chr20:47427789(-) A-I      intronic chr20:47409593(-) A-I      intronic chr20:47260391(-) A-I      intronic chr20:47318694(-) A-I      intronic chr20:47409594(-) A-I      intronic chr20:47280801(-) A-I      intronic chr20:47260314(-) A-I      intronic chr20:47264677(-) A-I      intronic chr20:47260323(-) A-I      intronic chr20:47426902(-) A-I      intronic chr20:47260000(-) A-I      intronic chr20:47381157(-) A-I      intronic chr20:47263151(-) A-I      intronic chr20:47427819(-) A-I      intronic chr20:47426863(-) A-I      intronic chr20:47264718(-) A-I      intronic chr20:47259844(-) A-I      intronic chr20:47264044(-) A-I      intronic chr20:47259885(-) A-I      intronic chr20:47260004(-) A-I      intronic chr20:47415615(-) A-I      intronic chr20:47350384(-) A-I      intronic chr20:47264517(-) A-I      intronic chr20:47260488(-) A-I      intronic chr20:47263164(-) A-I      intronic chr20:47259764(-) A-I      intronic chr20:47260288(-) A-I      intronic chr20:47263896(-) A-I      intronic chr20:47260274(-) A-I      intronic chr20:47318623(-) A-I      intronic chr20:47427824(-) A-I      intronic chr20:47426937(-) A-I      intronic chr20:47283358(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PREX1	chr20:47275797(-) T-G intron -    22484847 chr20:47436852(-) A-G intron -    22484847 chr20:47259841(-) A-G intron -    22484847 chr20:47260274(-) A-G intron -    22484847 chr20:47260288(-) A-G intron -    22484847 chr20:47260314(-) A-G intron -    22484847 chr20:47426863(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PREX1	chr20:47241212-47241213(-) m6A 3'UTR       27371828 chr20:47241327-47241328(-) m6A 3'UTR       24284625 chr20:47241827-47241828(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27371828//22608085 chr20:47241844-47241845(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27371828//22575960//22608085 chr20:47241926-47241927(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr20:47241937-47241938(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr20:47242042-47242043(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27371828 chr20:47242115-47242116(-) m6A 3'UTR       24284625//25456834//28052920//27371828 chr20:47242172-47242173(-) m6A 3'UTR       24284625//25456834//27371828 chr20:47242270-47242271(-) m6A 3'UTR       25456834//27371828//27773536 chr20:47242303-47242304(-) m6A 3'UTR       25456834//27371828//27773536 chr20:47242368-47242369(-) m6A 3'UTR       25456834//27371828//27773536 chr20:47242421-47242422(-) m6A 3'UTR       25456834//27371828 chr20:47242429-47242430(-) m6A 3'UTR//CDS       25456834//27371828 chr20:47244109-47244110(-) m6A 3'UTR//CDS       24284625//25456834//27371828 chr20:47244124-47244125(-) m6A 3'UTR//CDS       24284625//25456834//27371828 chr20:47244414-47244415(-) m6A 3'UTR//CDS       25456834//27371828 chr20:47251287-47251288(-) m6A CDS       - chr20:47251300-47251301(-) m6A CDS       - chr20:47266104-47266105(-) m6A CDS       - chr20:47266564-47266565(-) m6A CDS       24284625 chr20:47266611-47266612(-) m6A CDS       24284625 chr20:47266664-47266665(-) m6A CDS       24284625//27371828 chr20:47266702-47266703(-) m6A CDS       24284625//27371828 chr20:47268075-47268076(-) m6A CDS       27371828 chr20:47269137-47269138(-) m6A CDS       27371828 chr20:47269167-47269168(-) m6A CDS       27371828 chr20:47273679-47273680(-) m6A CDS       24284625//27371828 chr20:47274719-47274720(-) m6A CDS       24284625//27371828 chr20:47274746-47274747(-) m6A CDS       24284625//27371828 chr20:47276478-47276479(-) m6A CDS       24284625 chr20:47276514-47276515(-) m6A CDS       24284625 chr20:47276527-47276528(-) m6A CDS       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-UL148D	Exosome K562 cells     24460325
	PREX1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HeLa-S3 cells|K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL148D	Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL148D
Interactor2: PREX1

Evidence Support:

Prediction-Evidence	cRep//miRanda//RNAHybrid
Support Database	RepTar//VmiReg