Basic Information:

  VIRBase ID:  

VHID00224925

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL148D:  MIMAT0001578          SMCO4:  NM_020179     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL148D	SMCO4
miRBase Accession/Entrez ID	MIMAT0001578	56935
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	C11orf75//FN5

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SMCO4	chr11:93236999(-) A-I      intronic chr11:93242284(-) A-I      intronic chr11:93234651(-) A-I      intronic chr11:93240519(-) A-I      intronic chr11:93240326(-) A-I      intronic chr11:93239733(-) A-I      intronic chr11:93239743(-) A-I      intronic chr11:93240327(-) A-I      intronic chr11:93239737(-) A-I      intronic chr11:93239782(-) A-I      intronic chr11:93267239(-) A-I      intronic chr11:93239880(-) A-I      intronic chr11:93267274(-) A-I      intronic chr11:93267271(-) A-I      intronic chr11:93240514(-) A-I      intronic chr11:93268748(-) A-I      intronic chr11:93240314(-) A-I      intronic chr11:93240453(-) A-I      intronic chr11:93240556(-) A-I      intronic chr11:93240454(-) A-I      intronic chr11:93239879(-) A-I      intronic chr11:93242322(-) A-I      intronic chr11:93219272(-) A-I      intronic chr11:93240444(-) A-I      intronic chr11:93240520(-) A-I      intronic chr11:93256652(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SMCO4	chr11:93212114-93212115(-) m6A 3'UTR       27371828 chr11:93212155-93212156(-) m6A 3'UTR       24284625//24209618//25456834//27371828//27773536 chr11:93212311-93212312(-) m6A CDS       25456834//24981863//27773535//27371828//27773536 chr11:93212321-93212322(-) m6A CDS       25456834//24981863//27773535//27371828//27773536 chr11:93212383-93212384(-) m6A 5'UTR       25456834//27773535//27371828//27773536 chr11:93256521-93256522(-) m6A 5'UTR//intron       24209618//24981863 chr11:93263752-93263753(-) Am intron       - chr11:93271054-93271055(-) m6A 5'UTR//intron       24209618

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-UL148D	Exosome K562 cells     24460325
	SMCO4	Exosome Blood     - Nucleolus K562 cells     - Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL148D	Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL148D
Interactor2: SMCO4

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid
Support Database	VmiReg